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Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport.
Sauna ZE, Bohn SS, Rutledge R, Dougherty MP, Cronin S, May L, Xia D, Ambudkar SV, Golin J. Sauna ZE, et al. J Biol Chem. 2008 Dec 12;283(50):35010-22. doi: 10.1074/jbc.M806446200. Epub 2008 Oct 8. J Biol Chem. 2008. PMID: 18842589 Free PMC article.