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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 5
2004 10
2005 17
2006 30
2007 34
2008 34
2009 63
2010 66
2011 86
2012 119
2013 111
2014 151
2015 150
2016 172
2017 164
2018 171
2019 185
2020 166
2021 139
2022 56
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1,689 results
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Showing results for shrna feng
Search for Shuna Feng instead (1 results)
PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity.
Kim H, Kim H, Feng Y, Li Y, Tamiya H, Tocci S, Ronai ZA. Kim H, et al. Sci Transl Med. 2020 Jul 8;12(551):eaaz5683. doi: 10.1126/scitranslmed.aaz5683. Sci Transl Med. 2020. PMID: 32641491 Free PMC article.
Increased expression of IFI204 and NLRC5 was associated with decreased melanoma growth in murine models, and increased expression of IFI16 and NLRC5 correlated with prolonged survival of patients with melanoma. Combination of pharmacological (GSK3326595) or genetic (shRNA) …
Increased expression of IFI204 and NLRC5 was associated with decreased melanoma growth in murine models, and increased expression of IFI16 a …
Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis.
Long J, Walker J, She W, Aldridge B, Gao H, Deans S, Vickers M, Feng X. Long J, et al. Science. 2021 Jul 2;373(6550):eabh0556. doi: 10.1126/science.abh0556. Science. 2021. PMID: 34210850
We demonstrate that genic methylation in the male germline, from meiocytes to sperm, is established by 24-nucleotide small interfering RNAs (siRNAs) transcribed from transposons with imperfect sequence homology. ...
We demonstrate that genic methylation in the male germline, from meiocytes to sperm, is established by 24-nucleotide small interfe …
Plant 22-nt siRNAs mediate translational repression and stress adaptation.
Wu H, Li B, Iwakawa HO, Pan Y, Tang X, Ling-Hu Q, Liu Y, Sheng S, Feng L, Zhang H, Zhang X, Tang Z, Xia X, Zhai J, Guo H. Wu H, et al. Nature. 2020 May;581(7806):89-93. doi: 10.1038/s41586-020-2231-y. Epub 2020 Apr 29. Nature. 2020. PMID: 32376953
Small interfering RNAs (siRNAs) are essential for proper development and immunity in eukaryotes(1). ...Here we report the identification and characterization of a group of endogenous 22-nucleotide siRNAs that are generated by the DICER-LIKE 2 (DCL2) protein in plant …
Small interfering RNAs (siRNAs) are essential for proper development and immunity in eukaryotes(1). ...Here we report the iden …
Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Wang Q, Xue Y, Zhang L, Zhong Z, Feng S, Wang C, Xiao L, Yang Z, Harris CJ, Wu Z, Zhai J, Yang M, Li S, Jacobsen SE, Du J. Wang Q, et al. Science. 2021 Nov 26;374(6571):1152-1157. doi: 10.1126/science.abl4546. Epub 2021 Oct 14. Science. 2021. PMID: 34648373 Free PMC article.
In eukaryotes, small RNAs (sRNAs) play critical roles in multiple biological processes. ...In plants, DICER-LIKE PROTEIN 3 (DCL3) produces 24-nucleotide (nt) small interfering RNAs (siRNAs) that determine the specificity of the RNA-directed DNA methyla …
In eukaryotes, small RNAs (sRNAs) play critical roles in multiple biological processes. ...In plants, DICER-LIKE PROTEIN 3 (DCL3) pro …
ASF1B promotes cervical cancer progression through stabilization of CDK9.
Liu X, Song J, Zhang Y, Wang H, Sun H, Feng X, Hou M, Chen G, Tang Q, Ji M. Liu X, et al. Cell Death Dis. 2020 Aug 26;11(8):705. doi: 10.1038/s41419-020-02872-5. Cell Death Dis. 2020. PMID: 32848135 Free PMC article.
Furthermore, we established two murine models using stable ASF1B-shRNA HeLa cells or normal HeLa cells following AAV-shRNA-ASF1B administration to evaluate how suppression of ASF1B affects tumor growth. ...
Furthermore, we established two murine models using stable ASF1B-shRNA HeLa cells or normal HeLa cells following AAV-shRNA-ASF …
Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.
McDonald ER 3rd, de Weck A, Schlabach MR, Billy E, Mavrakis KJ, Hoffman GR, Belur D, Castelletti D, Frias E, Gampa K, Golji J, Kao I, Li L, Megel P, Perkins TA, Ramadan N, Ruddy DA, Silver SJ, Sovath S, Stump M, Weber O, Widmer R, Yu J, Yu K, Yue Y, Abramowski D, Ackley E, Barrett R, Berger J, Bernard JL, Billig R, Brachmann SM, Buxton F, Caothien R, Caushi JX, Chung FS, Cortés-Cros M, deBeaumont RS, Delaunay C, Desplat A, Duong W, Dwoske DA, Eldridge RS, Farsidjani A, Feng F, Feng J, Flemming D, Forrester W, Galli GG, Gao Z, Gauter F, Gibaja V, Haas K, Hattenberger M, Hood T, Hurov KE, Jagani Z, Jenal M, Johnson JA, Jones MD, Kapoor A, Korn J, Liu J, Liu Q, Liu S, Liu Y, Loo AT, Macchi KJ, Martin T, McAllister G, Meyer A, Mollé S, Pagliarini RA, Phadke T, Repko B, Schouwey T, Shanahan F, Shen Q, Stamm C, Stephan C, Stucke VM, Tiedt R, Varadarajan M, Venkatesan K, Vitari AC, Wallroth M, Weiler J, Zhang J, Mickanin C, Myer VE, Porter JA, Lai A, Bitter H, Lees E, Keen N, Kauffmann A, Stegmeier F, Hofmann F, Schmelzle T, Sellers WR. McDonald ER 3rd, et al. Cell. 2017 Jul 27;170(3):577-592.e10. doi: 10.1016/j.cell.2017.07.005. Cell. 2017. PMID: 28753431 Free article.
To identify vulnerabilities relevant to specific cancer subtypes, we conducted a large-scale RNAi screen in which viability effects of mRNA knockdown were assessed for 7,837 genes using an average of 20 shRNAs per gene in 398 cancer cell lines. We describe findings of this …
To identify vulnerabilities relevant to specific cancer subtypes, we conducted a large-scale RNAi screen in which viability effects of mRNA …
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice.
Tao W, Yurdagul A Jr, Kong N, Li W, Wang X, Doran AC, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. Tao W, et al. Sci Transl Med. 2020 Jul 22;12(553):eaay1063. doi: 10.1126/scitranslmed.aay1063. Sci Transl Med. 2020. PMID: 32718990 Free PMC article.
Atherosclerotic lesional macrophages express molecules that promote plaque progression, but lack of mechanisms to therapeutically target these molecules represents a major gap in translational cardiovascular research. Here, we tested the efficacy of a small interfering …
Atherosclerotic lesional macrophages express molecules that promote plaque progression, but lack of mechanisms to therapeutically target the …
1,689 results