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Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection.

Lou G, Anderluzzi G, Schmidt ST, Woods S, Gallorini S, Brazzoli M, Giusti F, Ferlenghi I, Johnson RN, Roberts CW, O'Hagan DT, Baudner BC, Perrie Y. Lou G, et al. Among authors: schmidt st. J Control Release. 2020 Sep 10;325:370-379. doi: 10.1016/j.jconrel.2020.06.027. Epub 2020 Jul 1. J Control Release. 2020. PMID: 32619745

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The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency.

Anderluzzi G, Lou G, Woods S, Schmidt ST, Gallorini S, Brazzoli M, Johnson R, Roberts CW, O'Hagan DT, Baudner BC, Perrie Y. Anderluzzi G, et al. Among authors: schmidt st. J Control Release. 2022 Feb;342:388-399. doi: 10.1016/j.jconrel.2021.12.008. Epub 2021 Dec 10. J Control Release. 2022. PMID: 34896446 Free PMC article.

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Rational Design and In Vivo Characterization of Vaccine Adjuvants.

Schmidt ST, Pedersen GK, Christensen D. Schmidt ST, et al. ILAR J. 2018 Dec 31;59(3):309-322. doi: 10.1093/ilar/ily018. ILAR J. 2018. PMID: 30624655 Free PMC article.

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Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators.

Tandrup Schmidt S, Foged C, Korsholm KS, Rades T, Christensen D. Tandrup Schmidt S, et al. Pharmaceutics. 2016 Mar 10;8(1):7. doi: 10.3390/pharmaceutics8010007. Pharmaceutics. 2016. PMID: 26978390 Free PMC article. Review.

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Rational design of adjuvants for subunit vaccines: The format of cationic adjuvants affects the induction of antigen-specific antibody responses.

Anderluzzi G, Schmidt ST, Cunliffe R, Woods S, Roberts CW, Veggi D, Ferlenghi I, O'Hagan DT, Baudner BC, Perrie Y. Anderluzzi G, et al. Among authors: schmidt st. J Control Release. 2021 Feb 10;330:933-944. doi: 10.1016/j.jconrel.2020.10.066. Epub 2020 Nov 2. J Control Release. 2021. PMID: 33152394

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Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice.

Wørzner K, Sheward DJ, Schmidt ST, Hanke L, Zimmermann J, McInerney G, Karlsson Hedestam GB, Murrell B, Christensen D, Pedersen GK. Wørzner K, et al. Among authors: schmidt st. EBioMedicine. 2021 Jan;63:103197. doi: 10.1016/j.ebiom.2020.103197. Epub 2021 Jan 7. EBioMedicine. 2021. PMID: 33422991 Free PMC article.

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Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction.

Wørzner K, Hvannastein J, Schmidt ST, Foged C, Rosenkrands I, Pedersen GK, Christensen D. Wørzner K, et al. Among authors: schmidt st. Eur J Pharm Biopharm. 2021 Aug;165:293-305. doi: 10.1016/j.ejpb.2021.05.020. Epub 2021 May 24. Eur J Pharm Biopharm. 2021. PMID: 34044110 Free PMC article.

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Applying Microfluidics for the Production of the Cationic Liposome-Based Vaccine Adjuvant CAF09b.

Schmidt ST, Christensen D, Perrie Y. Schmidt ST, et al. Pharmaceutics. 2020 Dec 19;12(12):1237. doi: 10.3390/pharmaceutics12121237. Pharmaceutics. 2020. PMID: 33352684 Free PMC article.

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Design of a novel vaccine nanotechnology-based delivery system comprising CpGODN-protein conjugate anchored to liposomes.

Chatzikleanthous D, Schmidt ST, Buffi G, Paciello I, Cunliffe R, Carboni F, Romano MR, O'Hagan DT, D'Oro U, Woods S, Roberts CW, Perrie Y, Adamo R. Chatzikleanthous D, et al. Among authors: schmidt st. J Control Release. 2020 Jul 10;323:125-137. doi: 10.1016/j.jconrel.2020.04.001. Epub 2020 Apr 2. J Control Release. 2020. PMID: 32247804

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The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics.

Webb C, Khadke S, Schmidt ST, Roces CB, Forbes N, Berrie G, Perrie Y. Webb C, et al. Among authors: schmidt st. Pharmaceutics. 2019 Dec 4;11(12):653. doi: 10.3390/pharmaceutics11120653. Pharmaceutics. 2019. PMID: 31817217 Free PMC article.

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