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1

IgG Binding Characteristics of Rhesus Macaque FcγR.

Chan YN, Boesch AW, Osei-Owusu NY, Emileh A, Crowley AR, Cocklin SL, Finstad SL, Linde CH, Howell RA, Zentner I, Cocklin S, Miles AR, Eckman JW, Alter G, Schmitz JE, Ackerman ME. Chan YN, et al. Among authors: Cocklin SL, Cocklin S. J Immunol. 2016 Oct 1;197(7):2936-47. doi: 10.4049/jimmunol.1502252. Epub 2016 Aug 24. J Immunol. 2016. PMID: 27559046 Free PMC article.

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2

The spliceosomal proteins PPIH and PRPF4 exhibit bi-partite binding.

Rajiv C, Jackson SR, Cocklin S, Eisenmesser EZ, Davis TL. Rajiv C, et al. Among authors: Cocklin S. Biochem J. 2017 Oct 25;474(21):3689-3704. doi: 10.1042/BCJ20170366. Biochem J. 2017. PMID: 28935721 Free PMC article.

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3

Core chemotype diversification in the HIV-1 entry inhibitor class using field-based bioisosteric replacement.

Tuyishime M, Lawrence R, Cocklin S. Tuyishime M, et al. Among authors: Cocklin S. Bioorg Med Chem Lett. 2016 Jan 1;26(1):228-34. doi: 10.1016/j.bmcl.2015.10.080. Epub 2015 Oct 27. Bioorg Med Chem Lett. 2016. PMID: 26531151 Free PMC article.

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4

Identification of a small molecule HIV-1 inhibitor that targets the capsid hexamer.

Xu JP, Branson JD, Lawrence R, Cocklin S. Xu JP, et al. Among authors: Cocklin S. Bioorg Med Chem Lett. 2016 Feb 1;26(3):824-828. doi: 10.1016/j.bmcl.2015.12.087. Epub 2015 Dec 25. Bioorg Med Chem Lett. 2016. PMID: 26747394 Free PMC article.

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5

Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors.

Huang F, Goyal N, Sullivan K, Hanamshet K, Patel M, Mazina OM, Wang CX, An WF, Spoonamore J, Metkar S, Emmitte KA, Cocklin S, Skorski T, Mazin AV. Huang F, et al. Among authors: Cocklin S. Nucleic Acids Res. 2016 May 19;44(9):4189-99. doi: 10.1093/nar/gkw087. Epub 2016 Feb 11. Nucleic Acids Res. 2016. PMID: 26873923 Free PMC article.

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6

Exploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action.

Xu JP, Francis AC, Meuser ME, Mankowski M, Ptak RG, Rashad AA, Melikyan GB, Cocklin S. Xu JP, et al. Among authors: Cocklin S. J Drug Des Res. 2018;5(2):1070. Epub 2018 Aug 13. J Drug Des Res. 2018. PMID: 30393786 Free PMC article.

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7

Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis.

Williams PA, Krug MS, McMillan EA, Peake JD, Davis TL, Cocklin S, Strochlic TI. Williams PA, et al. Among authors: Cocklin S. Mol Biol Cell. 2016 Aug 1;27(15):2341-50. doi: 10.1091/mbc.E15-11-0773. Epub 2016 Jun 8. Mol Biol Cell. 2016. PMID: 27280388 Free PMC article.

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8

Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library.

Wu G, Zalloum WA, Meuser ME, Jing L, Kang D, Chen CH, Tian Y, Zhang F, Cocklin S, Lee KH, Liu X, Zhan P. Wu G, et al. Among authors: Cocklin S. Eur J Med Chem. 2018 Oct 5;158:478-492. doi: 10.1016/j.ejmech.2018.09.029. Epub 2018 Sep 11. Eur J Med Chem. 2018. PMID: 30243152 Free PMC article.

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9

Interaction between the AAA⁺ ATPase p97 and its cofactor ataxin3 in health and disease: Nucleotide-induced conformational changes regulate cofactor binding.

Rao MV, Williams DR, Cocklin S, Loll PJ. Rao MV, et al. Among authors: Cocklin S. J Biol Chem. 2017 Nov 10;292(45):18392-18407. doi: 10.1074/jbc.M117.806281. Epub 2017 Sep 22. J Biol Chem. 2017. PMID: 28939772 Free PMC article.

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10

Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency.

Meuser ME, Murphy MB, Rashad AA, Cocklin S. Meuser ME, et al. Among authors: Cocklin S. Molecules. 2018 Aug 3;23(8):1940. doi: 10.3390/molecules23081940. Molecules. 2018. PMID: 30081466 Free PMC article.

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