Lurbinectedin as second- or third-line palliative therapy in malignant pleural mesothelioma: an international, multi-centre, single-arm, phase II trial (SAKK 17/16).
Metaxas Y, Früh M, Eboulet EI, Grosso F, Pless M, Zucali PA, Ceresoli GL, Mark M, Schneider M, Maconi A, Perrino M, Biaggi-Rudolf C, Froesch P, Schmid S, Waibel C, Appenzeller C, Rauch D, von Moos R; Swiss Group for Clinical Cancer Research (SAKK).
Metaxas Y, et al.
Ann Oncol. 2020 Apr;31(4):495-500. doi: 10.1016/j.annonc.2019.12.009. Epub 2020 Jan 16.
Ann Oncol. 2020.
PMID: 32085891
Free article.
Clinical Trial.
Treatment was given intravenously at 3.2 mg/m(2) dose every 3 weeks until progression or unacceptable toxicity. Using Simon's two-stage design, the primary endpoint, progression-free survival (PFS) at 12 weeks (PFS(12wks)), was met if achieved by 21 pts (p0 35% vers …
Treatment was given intravenously at 3.2 mg/m(2) dose every 3 weeks until progression or unacceptable toxicity. Using Simon's …