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iPla2β deficiency in mice fed with MCD diet does not correct the defect of phospholipid remodeling but attenuates hepatocellular injury via an inhibition of lipid uptake genes.
Zhu X, Gan-Schreier H, Otto AC, Cheng Y, Staffer S, Tuma-Kellner S, Ganzha A, Liebisch G, Chamulitrat W. Zhu X, et al. Among authors: staffer s. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):677-687. doi: 10.1016/j.bbalip.2019.02.003. Epub 2019 Feb 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30735854
Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling.
Otto AC, Gan-Schreier H, Zhu X, Tuma-Kellner S, Staffer S, Ganzha A, Liebisch G, Chamulitrat W. Otto AC, et al. Among authors: staffer s. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):662-676. doi: 10.1016/j.bbalip.2019.01.012. Epub 2019 Feb 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30735855
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