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Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA.
Ngo J, Choi DW, Stanley IA, Stiles L, Molina AJA, Chen PH, Lako A, Sung ICH, Goswami R, Kim MY, Miller N, Baghdasarian S, Kim-Vasquez D, Jones AE, Roach B, Gutierrez V, Erion K, Divakaruni AS, Liesa M, Danial NN, Shirihai OS. Ngo J, et al. Among authors: baghdasarian s. EMBO J. 2023 Jun 1;42(11):e111901. doi: 10.15252/embj.2022111901. Epub 2023 Mar 14. EMBO J. 2023. PMID: 36917141 Free PMC article.
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.
Acin-Perez R, Benincá C, Fernandez Del Rio L, Shu C, Baghdasarian S, Zanette V, Gerle C, Jiko C, Khairallah R, Khan S, Rincon Fernandez Pacheco D, Shabane B, Erion K, Masand R, Dugar S, Ghenoiu C, Schreiner G, Stiles L, Liesa M, Shirihai OS. Acin-Perez R, et al. Among authors: baghdasarian s. EMBO J. 2023 May 15;42(10):e111699. doi: 10.15252/embj.2022111699. Epub 2023 Mar 13. EMBO J. 2023. PMID: 36912136 Free PMC article.
Recruitment and remodeling of peridroplet mitochondria in human adipose tissue.
Acín-Perez R, Petcherski A, Veliova M, Benador IY, Assali EA, Colleluori G, Cinti S, Brownstein AJ, Baghdasarian S, Livhits MJ, Yeh MW, Krishnan KC, Vergnes L, Winn NC, Padilla J, Liesa M, Sacks HS, Shirihai OS. Acín-Perez R, et al. Among authors: baghdasarian s. Redox Biol. 2021 Oct;46:102087. doi: 10.1016/j.redox.2021.102087. Epub 2021 Jul 30. Redox Biol. 2021. PMID: 34411987 Free PMC article.
Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.
Shum M, Segawa M, Gharakhanian R, Viñuela A, Wortham M, Baghdasarian S, Wolf DM, Sereda SB, Nocito L, Stiles L, Zhou Z, Gutierrez V, Sander M, Shirihai OS, Liesa M. Shum M, et al. Among authors: baghdasarian s. Mol Metab. 2022 Jan;55:101403. doi: 10.1016/j.molmet.2021.101403. Epub 2021 Nov 23. Mol Metab. 2022. PMID: 34823065 Free PMC article.
Mitochondrial Proton Leak Regulated by Cyclophilin D Elevates Insulin Secretion in Islets at Nonstimulatory Glucose Levels.
Taddeo EP, Alsabeeh N, Baghdasarian S, Wikstrom JD, Ritou E, Sereda S, Erion K, Li J, Stiles L, Abdulla M, Swanson Z, Wilhelm JJ, Bellin MD, Kibbey RG, Liesa M, Shirihai OS. Taddeo EP, et al. Among authors: baghdasarian s. Diabetes. 2020 Feb;69(2):131-145. doi: 10.2337/db19-0379. Epub 2019 Nov 18. Diabetes. 2020. PMID: 31740442 Free PMC article.
Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2.
Wortham M, Ramms B, Zeng C, Benthuysen JR, Sai S, Pollow DP, Liu F, Schlichting M, Harrington AR, Liu B, Prakash TP, Pirie EC, Zhu H, Baghdasarian S, Auwerx J, Shirihai OS, Sander M. Wortham M, et al. Among authors: baghdasarian s. bioRxiv [Preprint]. 2024 Feb 28:2024.02.24.581864. doi: 10.1101/2024.02.24.581864. bioRxiv. 2024. PMID: 38464227 Free PMC article. Preprint.