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2018 3
2019 2
2020 2
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Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy.
Laible M, Hartmann K, Gürtler C, Anzeneder T, Wirtz R, Weber S, Keller T, Sahin U, Rees M, Ramaswamy A. Laible M, et al. BMC Cancer. 2019 Jul 15;19(1):694. doi: 10.1186/s12885-019-5890-z. BMC Cancer. 2019. PMID: 31307414 Free PMC article. Clinical Trial.
BACKGROUND: Current evidence suggests that patients with Luminal A early breast cancer can skip chemotherapy or extended endocrine therapy, but immunohistochemistry-based biomarker analysis for St Gallen subtyping may not be reproducible. ...
BACKGROUND: Current evidence suggests that patients with Luminal A early breast cancer can skip chemotherapy or extended endocrine th …
SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain.
Sanger A, Yip YY, Randall TS, Pernigo S, Steiner RA, Dodding MP. Sanger A, et al. J Cell Sci. 2017 May 1;130(9):1637-1651. doi: 10.1242/jcs.198267. Epub 2017 Mar 16. J Cell Sci. 2017. PMID: 28302907 Free PMC article.
Mutational separation of KHC and KLC binding shows that both interactions are important for SKIP-kinesin-1 interaction in vitro and that KHC binding is important for lysosome transport in vivo However, in the absence of KLCs, SKIP can only bind to KHC when autoinhib …
Mutational separation of KHC and KLC binding shows that both interactions are important for SKIP-kinesin-1 interaction in vitro and t …
The impact of menstrual symptoms on everyday life: a survey among 42,879 women.
Schoep ME, Nieboer TE, van der Zanden M, Braat DDM, Nap AW. Schoep ME, et al. Am J Obstet Gynecol. 2019 Jun;220(6):569.e1-569.e7. doi: 10.1016/j.ajog.2019.02.048. Epub 2019 Mar 15. Am J Obstet Gynecol. 2019. PMID: 30885768
From the women that had to skip tasks because of their symptoms, only 48.6% told their family that menstrual symptoms were the reason for the transfer of tasks. ...
From the women that had to skip tasks because of their symptoms, only 48.6% told their family that menstrual symptoms were the reason …
Assessment of lymph node involvement in colorectal cancer.
Ong ML, Schofield JB. Ong ML, et al. World J Gastrointest Surg. 2016 Mar 27;8(3):179-92. doi: 10.4240/wjgs.v8.i3.179. World J Gastrointest Surg. 2016. PMID: 27022445 Free PMC article. Review.
With further development and refinement, intra-operative lymphatic mapping and sentinel lymph node biopsy may provide a guide to the optimum extent of lymphadenectomy, but in its present form, it is beset by false negatives, skip lesions and failures to identify a sentinel …
With further development and refinement, intra-operative lymphatic mapping and sentinel lymph node biopsy may provide a guide to the optimum …
The multi-tasking P-TEFb complex.
Brès V, Yoh SM, Jones KA. Brès V, et al. Curr Opin Cell Biol. 2008 Jun;20(3):334-40. doi: 10.1016/j.ceb.2008.04.008. Epub 2008 May 29. Curr Opin Cell Biol. 2008. PMID: 18513937 Free PMC article. Review.
Brd4 activates growth-related genes in the G1 phase of the cell cycle and can also tether P-TEFb to mitotic chromosomes, possibly to mark sites of active transcription throughout cell division. P-TEFb co-operates with c-Myc during transactivation and cell transformation, a …
Brd4 activates growth-related genes in the G1 phase of the cell cycle and can also tether P-TEFb to mitotic chromosomes, possibly to mark
NS-kNN: a modified k-nearest neighbors approach for imputing metabolomics data.
Lee JY, Styczynski MP. Lee JY, et al. Metabolomics. 2018 Nov 23;14(12):153. doi: 10.1007/s11306-018-1451-8. Metabolomics. 2018. PMID: 30830437 Free PMC article.
We present a new model for generating synthetic missing data and a new algorithm, No-Skip kNN (NS-kNN), that accounts for MNAR values to provide more accurate imputations. ...
We present a new model for generating synthetic missing data and a new algorithm, No-Skip kNN (NS-kNN), that accounts for MNAR values …
Viral status, immune microenvironment and immunological response to checkpoint inhibitors in hepatocellular carcinoma.
Ho WJ, Danilova L, Lim SJ, Verma R, Xavier S, Leatherman JM, Sztein MB, Fertig EJ, Wang H, Jaffee E, Yarchoan M. Ho WJ, et al. J Immunother Cancer. 2020 Apr;8(1):e000394. doi: 10.1136/jitc-2019-000394. J Immunother Cancer. 2020. PMID: 32303615 Free PMC article.
When celibacy matters: incorporating non-breeders improves demographic parameter estimates.
Pardo D, Weimerskirch H, Barbraud C. Pardo D, et al. PLoS One. 2013;8(3):e60389. doi: 10.1371/journal.pone.0060389. Epub 2013 Mar 29. PLoS One. 2013. PMID: 23555965 Free PMC article.
In this species, the breeding cycle lasts almost a year and birds that succeed a given year tend to skip the next breeding occasion while birds that fail tend to breed again the following year. ...Using multi-state capture-mark-recapture analyses, we used several me …
In this species, the breeding cycle lasts almost a year and birds that succeed a given year tend to skip the next breeding occasion w …
Robust estimates of a high Ne/N ratio in a top marine predator, southern bluefin tuna.
Waples RS, Grewe PM, Bravington MW, Hillary R, Feutry P. Waples RS, et al. Sci Adv. 2018 Jul 18;4(7):eaar7759. doi: 10.1126/sciadv.aar7759. eCollection 2018 Jul. Sci Adv. 2018. PMID: 30035218 Free PMC article.
A recent study using close-kin mark-recapture methods estimated adult abundance at N ≈ 2 × 10(6) for southern bluefin tuna (SBT), a highly fecund top predator that supports a lucrative (~$1 billion/year) fishery. ...Demographic estimates, which accounted for age-specific v …
A recent study using close-kin mark-recapture methods estimated adult abundance at N ≈ 2 × 10(6) for southern bluefin tuna (SBT), a h …
Interacting effects of unobserved heterogeneity and individual stochasticity in the life history of the southern fulmar.
Jenouvrier S, Aubry LM, Barbraud C, Weimerskirch H, Caswell H. Jenouvrier S, et al. J Anim Ecol. 2018 Jan;87(1):212-222. doi: 10.1111/1365-2656.12752. Epub 2017 Oct 10. J Anim Ecol. 2018. PMID: 28886208 Free PMC article.
We applied multievent, multistate mark-recapture methods to estimate a finite mixture model accounting for UH in all vital rates and Markov chain methods to calculate demographic outcomes. ...We identify three UH groups, differing substantially in longevity, lifetime repro …
We applied multievent, multistate mark-recapture methods to estimate a finite mixture model accounting for UH in all vital rates and …
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