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Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis.
Hsu YH, Li HH, Hsieh MY, Liu MF, Huang KY, Chin LS, Chen PC, Cheng HH, Chang MS. Hsu YH, et al. Arthritis Rheum. 2006 Sep;54(9):2722-33. doi: 10.1002/art.22039. Arthritis Rheum. 2006. PMID: 16947773 Free article.
IL-20 induced RASFs to secrete monocyte chemoattractant protein 1, IL-6, and IL-8, and it promoted neutrophil chemotaxis, RASF migration, and endothelial cell proliferation. Both IL-20 and IL-20RI were up-regulated in the rat CIA model. In vivo, electroporated sIL-20RI
IL-20 induced RASFs to secrete monocyte chemoattractant protein 1, IL-6, and IL-8, and it promoted neutrophil chemotaxis, RASF migration, an …