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91 results

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Page 1
Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in People with Cystic Fibrosis: A Clinical Trial.
Nichols DP, Paynter AC, Heltshe SL, Donaldson SH, Frederick CA, Freedman SD, Gelfond D, Hoffman LR, Kelly A, Narkewicz MR, Pittman JE, Ratjen F, Rosenfeld M, Sagel SD, Schwarzenberg SJ, Singh PK, Solomon GM, Stalvey MS, Clancy JP, Kirby S, Van Dalfsen JM, Kloster MH, Rowe SM; PROMISE Study group. Nichols DP, et al. Among authors: heltshe sl. Am J Respir Crit Care Med. 2022 Mar 1;205(5):529-539. doi: 10.1164/rccm.202108-1986OC. Am J Respir Crit Care Med. 2022. PMID: 34784492 Free PMC article.
Biomarkers for cystic fibrosis drug development.
Muhlebach MS, Clancy JP, Heltshe SL, Ziady A, Kelley T, Accurso F, Pilewski J, Mayer-Hamblett N, Joseloff E, Sagel SD. Muhlebach MS, et al. Among authors: heltshe sl. J Cyst Fibros. 2016 Nov;15(6):714-723. doi: 10.1016/j.jcf.2016.10.009. Epub 2016 Oct 27. J Cyst Fibros. 2016. PMID: 28215711 Free PMC article. Review.
Long-term Reductions in Inflammation in People with Cystic Fibrosis Treated with Elexacaftor/Tezacaftor/Ivacaftor.
Sagel SD, Poore TS, Wagner BD, Xie J, Heltshe SL, Cross M, Bratcher PE, Taylor-Cousar JL, Wilson A, McBennett K, Morgan SJ, Singh PK, Nichols DP, Kelly A, Solomon GM. Sagel SD, et al. Among authors: heltshe sl. Ann Am Thorac Soc. 2025 Sep 17:10.1513/AnnalsATS.202507-817OC. doi: 10.1513/AnnalsATS.202507-817OC. Online ahead of print. Ann Am Thorac Soc. 2025. PMID: 40961158 Free PMC article.
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation.
Durfey SL, Kapnadak SG, Pena T, Willmering MM, Godwin JD, Teresi ME, Heltshe SL, Vo AT, Villacreses RA, Aliukonyte I, Boyken L, Stroik MR, Morgan SJ, Wang GM, Betts HL, Zhang S, Goss CH, Clancy JP, Aitken ML, Steele C, Feder AF, Esther CR Jr, Tiddens HAWM, Woods JC, Stoltz DA, Singh PK. Durfey SL, et al. Among authors: heltshe sl. Cell Host Microbe. 2025 Aug 13;33(8):1428-1445.e4. doi: 10.1016/j.chom.2025.07.009. Epub 2025 Aug 5. Cell Host Microbe. 2025. PMID: 40769150 Free article.
Role of hyperglycemia in cystic fibrosis pulmonary exacerbations.
Merjaneh L, Sidhaye AR, Vu PT, Heltshe SL, Goss CH, Flume PA, Kelly A, Rosenfeld M on behalf of the STOP2 investigators. Merjaneh L, et al. Among authors: heltshe sl. J Cyst Fibros. 2023 Sep;22(5):868-874. doi: 10.1016/j.jcf.2023.06.011. Epub 2023 Jun 30. J Cyst Fibros. 2023. PMID: 37394317 Free PMC article.
Does Ivacaftor Taken Twice a Day Keep the Pseudomonas Away?
Gifford AH, Heltshe SL. Gifford AH, et al. Among authors: heltshe sl. Ann Am Thorac Soc. 2019 Nov;16(11):1366-1367. doi: 10.1513/AnnalsATS.201908-596ED. Ann Am Thorac Soc. 2019. PMID: 31674815 No abstract available.
91 results