KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney.
medRxiv. 2022 Jan 11:2020.09.16.20190694. doi: 10.1101/2020.09.16.20190694. Preprint.
medRxiv. 2022.
PMID: 32995803
Free PMC article.
Uptake was inhibited by anti-KIM-1 antibodies and TW-37, a newly discovered inhibitor of KIM-1-mediated endocytosis. ...Thus, KIM-1 is an alternative receptor to ACE2 for SARS-CoV-2. KIM-1 targeted therapeutics may prevent and/or treat COVID-19....
Uptake was inhibited by anti-KIM-1 antibodies and TW-37, a newly discovered inhibitor of KIM-1-mediated endocytosis. ...Thus, …