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Page 1
Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.
Pecnard S, Provot O, Levaique H, Bignon J, Askenatzis L, Saller F, Borgel D, Michallet S, Laisne MC, Lafanechère L, Alami M, Hamze A. Pecnard S, et al. Among authors: michallet s. Eur J Med Chem. 2021 Jan 1;209:112873. doi: 10.1016/j.ejmech.2020.112873. Epub 2020 Oct 4. Eur J Med Chem. 2021. PMID: 33038796
Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors.
Hauguel C, Ducellier S, Provot O, Ibrahim N, Lamaa D, Balcerowiak C, Letribot B, Nascimento M, Blanchard V, Askenatzis L, Levaique H, Bignon J, Baschieri F, Bauvais C, Bollot G, Renko D, Deroussent A, Prost B, Laisne MC, Michallet S, Lafanechère L, Papot S, Montagnac G, Tran C, Alami M, Apcher S, Hamze A. Hauguel C, et al. Among authors: michallet s. Eur J Med Chem. 2022 Oct 5;240:114573. doi: 10.1016/j.ejmech.2022.114573. Epub 2022 Jul 1. Eur J Med Chem. 2022. PMID: 35797900 Free article.
Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells.
Peronne L, Denarier E, Rai A, Prudent R, Vernet A, Suzanne P, Ramirez-Rios S, Michallet S, Guidetti M, Vollaire J, Lucena-Agell D, Ribba AS, Josserand V, Coll JL, Dallemagne P, Díaz JF, Oliva MÁ, Sadoul K, Akhmanova A, Andrieux A, Lafanechère L. Peronne L, et al. Among authors: michallet s. Cancers (Basel). 2020 Aug 6;12(8):2196. doi: 10.3390/cancers12082196. Cancers (Basel). 2020. PMID: 32781579 Free PMC article.
Preventing neuropathy and improving anti-cancer chemotherapy with a carbazole-based compound.
Bosc L, Pero ME, Balayssac D, Jacquemot N, Allard J, Suzanne P, Vollaire J, Cottet-Rousselle C, Michallet S, Villaret J, Torch S, Marais S, Elena-Herrmann B, Schlattner U, Mercier A, Josserand V, Thibert C, Dallemagne P, Bartolini F, Lafanechère L. Bosc L, et al. Among authors: michallet s. bioRxiv [Preprint]. 2025 Mar 13:2025.03.10.642317. doi: 10.1101/2025.03.10.642317. bioRxiv. 2025. PMID: 40161707 Free PMC article. Preprint.
Synthesis and Antiproliferative Effect of 3,4,5-Trimethoxylated Chalcones on Colorectal and Prostatic Cancer Cells.
Letulle C, Toublet FX, Pinon A, Hba S, Laurent A, Sol V, Fagnère C, Rioux B, Allais F, Michallet S, Lafanechère L, Limami Y, Oudghiri M, Othman M, Daïch A, Liagre B, Lawson AM, Pouget C. Letulle C, et al. Among authors: michallet s. Pharmaceuticals (Basel). 2024 Sep 13;17(9):1207. doi: 10.3390/ph17091207. Pharmaceuticals (Basel). 2024. PMID: 39338369 Free PMC article.
A New Quantitative Cell-Based Assay Reveals Unexpected Microtubule Stabilizing Activity of Certain Kinase Inhibitors, Clinically Approved or in the Process of Approval.
Ramirez-Rios S, Michallet S, Peris L, Barette C, Rabat C, Feng Y, Fauvarque MO, Andrieux A, Sadoul K, Lafanechère L. Ramirez-Rios S, et al. Among authors: michallet s. Front Pharmacol. 2020 Apr 30;11:543. doi: 10.3389/fphar.2020.00543. eCollection 2020. Front Pharmacol. 2020. PMID: 32425788 Free PMC article.