Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1924 1
1925 1
1926 2
1929 3
1930 1
1934 1
1937 1
1939 1
1947 1
1950 2
1951 2
1953 2
1955 2
1956 1
1959 1
1960 1
1961 2
1962 2
1963 3
1964 1
1965 6
1966 4
1967 3
1968 1
1969 1
1970 6
1971 4
1972 8
1973 8
1974 15
1975 30
1976 23
1977 30
1978 38
1979 36
1980 41
1981 45
1982 53
1983 67
1984 75
1985 72
1986 99
1987 91
1988 90
1989 126
1990 111
1991 126
1992 133
1993 117
1994 114
1995 139
1996 125
1997 116
1998 103
1999 119
2000 105
2001 111
2002 112
2003 125
2004 149
2005 146
2006 157
2007 162
2008 159
2009 181
2010 216
2011 245
2012 291
2013 313
2014 315
2015 298
2016 327
2017 310
2018 318
2019 326
2020 375
2021 515
2022 503
2023 471
2024 479
2025 414
2026 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

8,510 results

Results by year

Filters applied: . Clear all
The following term was not found in PubMed: Soumak
Page 1
Did you mean souma, nao (5 results)?
Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation.
Wang Y, Chen C, Chen J, Sang T, Peng H, Lin X, Zhao Q, Chen S, Eling T, Wang X. Wang Y, et al. Redox Biol. 2022 Jun;52:102322. doi: 10.1016/j.redox.2022.102322. Epub 2022 Apr 27. Redox Biol. 2022. PMID: 35504134 Free PMC article.
Furthermore, NAG-1/GDF15 overexpression attenuated FFA-induced triglyceride (TG) accumulation, lipid metabolism deregulation, and AIM2 inflammasome activation in hepatic steatotic cells, while knockdown of NAG-1/GDF15 demonstrated opposite effects. Moreover, NAG …
Furthermore, NAG-1/GDF15 overexpression attenuated FFA-induced triglyceride (TG) accumulation, lipid metabolism deregulation, and AIM …
NAG-1/GDF15 inhibits diabetic nephropathy via inhibiting AGE/RAGE-mediated inflammation signaling pathways in C57BL/6 mice and HK-2 cells.
Chen J, Peng H, Chen C, Wang Y, Sang T, Cai Z, Zhao Q, Chen S, Lin X, Eling T, Wang X. Chen J, et al. Life Sci. 2022 Dec 15;311(Pt A):121142. doi: 10.1016/j.lfs.2022.121142. Epub 2022 Oct 29. Life Sci. 2022. PMID: 36367498
AIMS: Our previous studies showed that the nonsteroidal anti-inflammatory drug-activated gene-1, or growth differentiation factor-15 (NAG-1/GDF15) inhibits obesity and diabetes in mice. The current study aimed to examine the role and molecular mechanisms of NAG-1/GD …
AIMS: Our previous studies showed that the nonsteroidal anti-inflammatory drug-activated gene-1, or growth differentiation factor-15 (NAG …
Revisiting the Role of NAG across the Continuum of Kidney Disease.
Novak R, Salai G, Hrkac S, Vojtusek IK, Grgurevic L. Novak R, et al. Bioengineering (Basel). 2023 Apr 4;10(4):444. doi: 10.3390/bioengineering10040444. Bioengineering (Basel). 2023. PMID: 37106631 Free PMC article. Review.
The potential use of glycosidases, enzymes involved in carbohydrate metabolism, in kidney disease detection has been under investigation since the 1960s. N-acetyl-beta-D-glucosaminidase (NAG) is a glycosidase commonly found in proximal tubule epithelial cells (PTECs). Due …
The potential use of glycosidases, enzymes involved in carbohydrate metabolism, in kidney disease detection has been under investigation sin …
NAG-1/GDF15 protects against streptozotocin-induced type 1 diabetes by inhibiting apoptosis, preserving beta-cell function, and suppressing inflammation in pancreatic islets.
Wang Y, Chen J, Sang T, Chen C, Peng H, Lin X, Zhao Q, Chen S, Eling T, Wang X. Wang Y, et al. Mol Cell Endocrinol. 2022 Jun 1;549:111643. doi: 10.1016/j.mce.2022.111643. Epub 2022 Apr 6. Mol Cell Endocrinol. 2022. PMID: 35398052
However, the regulatory role of NAG-1/GDF15 in the structure and function of beta-cells and the prevention of T1DM is largely unknown. In the current study, we reported that NAG-1/GDF15 transgenic (Tg) mice are resistant to diabetogenesis induced by multiple low-dos …
However, the regulatory role of NAG-1/GDF15 in the structure and function of beta-cells and the prevention of T1DM is largely unknown …
NAG-1/GDF-15 Transgenic Female Mouse Shows Delayed Peak Period of the Second Phase Nociception in Formalin-induced Inflammatory Pain.
Choi SR, Lee J, Moon JY, Baek SJ, Lee JH. Choi SR, et al. Exp Neurobiol. 2023 Aug 31;32(4):247-258. doi: 10.5607/en23019. Exp Neurobiol. 2023. PMID: 37749926 Free PMC article.
Non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1), also known as growth differentiation factor-15 (GDF-15), is associated with cancer, diabetes, and inflammation, while there is limited understanding of the role of NAG-1 in nociception. ...There was no d …
Non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1), also known as growth differentiation factor-15 (GDF-15), is associated …
The role of NAG (N-acetyl-beta-D-glucosaminidase) in the diagnosis of kidney disease including the monitoring of nephrotoxicity.
Price RG. Price RG. Clin Nephrol. 1992;38 Suppl 1:S14-9. Clin Nephrol. 1992. PMID: 1295704 Review.
The assay of urinary N-acetyl-beta-D-glucosaminidase (NAG) provides an early indication of tubular dysfunction resulting from renal disease or nephrotoxic damage. ...The assay of NAG isoenzymes increases the diagnostic potential of this test while the availability o …
The assay of urinary N-acetyl-beta-D-glucosaminidase (NAG) provides an early indication of tubular dysfunction resulting from renal d …
NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins.
Tachibana I, Bodorova J, Berditchevski F, Zutter MM, Hemler ME. Tachibana I, et al. J Biol Chem. 1997 Nov 14;272(46):29181-9. doi: 10.1074/jbc.272.46.29181. J Biol Chem. 1997. PMID: 9360996 Free article.
These included an integrin (alpha6beta1) and three different TM4SF proteins (CD9, CD63, and NAG-2). The protein NAG-2 (novel antigen-2) is a previously unknown 30-kDa cell-surface protein. Using an expression cloning protocol, cDNA encoding NAG-2 was isolated …
These included an integrin (alpha6beta1) and three different TM4SF proteins (CD9, CD63, and NAG-2). The protein NAG-2 (novel a …
NaG: a sodium channel-like mRNA shared by Schwann cells and other neural crest derivatives.
Felts PA, Black JA, Dib-Hajj SD, Waxman SG. Felts PA, et al. Glia. 1997 Nov;21(3):269-76. doi: 10.1002/(sici)1098-1136(199711)21:3<269::aid-glia2>3.0.co;2-0. Glia. 1997. PMID: 9383036
In the present study, we used non-isotopic in situ hybridization with a riboprobe for NaG, in conjunction with RT-PCR, to determine whether NaG is expressed in tissues related to the DRG either by neural crest origin or sensory function. We found that the expression …
In the present study, we used non-isotopic in situ hybridization with a riboprobe for NaG, in conjunction with RT-PCR, to determine w …
The diagnostic role of urinary N-acetyl-beta-D-glucosaminidase (NAG) activity in the detection of renal tubular impairment.
Skálová S. Skálová S. Acta Medica (Hradec Kralove). 2005;48(2):75-80. Acta Medica (Hradec Kralove). 2005. PMID: 16259316 Review.
The urinary excretion of enzymes, in particular N-acetyl-beta-D-glucosaminidase (NAG), is considered a relatively simple, cheap, fast and non-invasive method in the detection and follow-up of renal tubular function under various conditions. ...This paper gives an overview …
The urinary excretion of enzymes, in particular N-acetyl-beta-D-glucosaminidase (NAG), is considered a relatively simple, cheap, fast …
NAG-targeting fluorescence based probe for precision diagnosis of kidney injury.
Yan F , Tian X , Luan Z , Feng L , Ma X , James TD . Yan F , et al. Chem Commun (Camb). 2019 Feb 7;55(13):1955-1958. doi: 10.1039/c8cc10311a. Chem Commun (Camb). 2019. PMID: 30681673
We report an enzyme-activated fluorescence based probe (NHPO) for the selective detection of N-acetyl-beta-d-glucosaminidase (NAG) activity in a drug-induced kidney injury mice model and NAG level in crude human urine. We used NHPO to explore the biological function …
We report an enzyme-activated fluorescence based probe (NHPO) for the selective detection of N-acetyl-beta-d-glucosaminidase (NAG) ac …
8,510 results