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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1909 1
1921 1
1922 1
1930 1
1932 1
1933 2
1946 3
1947 4
1948 3
1949 2
1950 9
1951 10
1952 1
1953 7
1954 5
1955 6
1956 12
1957 10
1958 15
1959 18
1960 22
1961 18
1962 23
1963 39
1964 29
1965 35
1966 37
1967 62
1968 52
1969 57
1970 72
1971 65
1972 75
1973 78
1974 83
1975 72
1976 75
1977 64
1978 80
1979 70
1980 59
1981 62
1982 62
1983 64
1984 87
1985 88
1986 81
1987 74
1988 99
1989 89
1990 119
1991 90
1992 108
1993 135
1994 141
1995 147
1996 151
1997 129
1998 160
1999 192
2000 220
2001 234
2002 229
2003 262
2004 303
2005 326
2006 369
2007 368
2008 508
2009 477
2010 566
2011 545
2012 624
2013 651
2014 624
2015 679
2016 633
2017 678
2018 652
2019 680
2020 703
2021 698
2022 683
2023 407

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14,460 results

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Filters applied: . Clear all The following term was not found in PubMed: Koulouzis
Page 1
Comparative efficacy and safety of albuterol sulfate Spiros inhaler and albuterol metered-dose inhaler in asthma.
Nelson H, Kemp JP, Bieler S, Vaughan LM, Hill MR. Nelson H, et al. Chest. 1999 Feb;115(2):329-35. doi: 10.1378/chest.115.2.329. Chest. 1999. PMID: 10027428 Clinical Trial.
RESULTS: Over the length of the study, the Spiros and MDI groups were comparable in all FEV1 parameters. Both active treatment groups were superior to the placebo group for each FEV1 parameter at all visits. ...CONCLUSION: Both active treatments were superior to the placeb …
RESULTS: Over the length of the study, the Spiros and MDI groups were comparable in all FEV1 parameters. Both active treatment groups …
Editorial overview: Environmental biotechnology.
Agathos SN, Boon N. Agathos SN, et al. Curr Opin Biotechnol. 2015 Jun;33:v-vii. doi: 10.1016/j.copbio.2015.04.002. Epub 2015 Apr 27. Curr Opin Biotechnol. 2015. PMID: 25936675 No abstract available.
Standardized Protocol Items Recommendations for Observational Studies (SPIROS) for Observational Study Protocol Reporting Guidelines: Protocol for a Delphi Study.
Mahajan R, Burza S, Bouter LM, Sijtsma K, Knottnerus A, Kleijnen J, Dael PV, Zeegers MP. Mahajan R, et al. JMIR Res Protoc. 2020 Oct 21;9(10):e17864. doi: 10.2196/17864. JMIR Res Protoc. 2020. PMID: 33084592 Free PMC article.
OBJECTIVE: The aim of this study is to formulate the Standardized Protocol Items Recommendations for Observational Studies (SPIROS) reporting guidelines, which focus on 3 main study designs of analytical epidemiology: cohort, case-control, and cross-sectional studies. METH …
OBJECTIVE: The aim of this study is to formulate the Standardized Protocol Items Recommendations for Observational Studies (SPIROS) r …
Therapeutic equivalence of Spiros dry powder inhaler and Ventolin metered dose inhaler. A bioassay using methacholine.
Ahrens RC, Hendeles L, Clarke WR, Dockhorn RJ, Hill MR, Vaughan LM, Lux C, Han SH. Ahrens RC, et al. Am J Respir Crit Care Med. 1999 Oct;160(4):1238-43. doi: 10.1164/ajrccm.160.4.9806101. Am J Respir Crit Care Med. 1999. PMID: 10508813 Clinical Trial.
In terms of delivery of albuterol to the lungs, we compared an alternative delivery system, the Spiros dry-powder inhaler (DPI), with Ventolin, using a methacholine challenge-based clinical bioassay. ...By using Finney 2-by-2 bioassay analysis, we estimate that each Spi …
In terms of delivery of albuterol to the lungs, we compared an alternative delivery system, the Spiros dry-powder inhaler (DPI), with …
Gold-catalyzed spiro-N,O-ketal synthesis.
Grammatikopoulou M, Thysiadis S, Sarli V. Grammatikopoulou M, et al. Org Biomol Chem. 2015 Jan 28;13(4):1169-78. doi: 10.1039/c4ob02050b. Epub 2014 Nov 27. Org Biomol Chem. 2015. PMID: 25427870
An efficient method for the synthesis of spiro-N,O-ketals with 5- and 6-membered rings was developed via a gold-catalyzed spiroamidoketalization of alkynyl amidoalcohols under mild conditions. This methodology has been successfully applied to the synthesis of a spiro …
An efficient method for the synthesis of spiro-N,O-ketals with 5- and 6-membered rings was developed via a gold-catalyzed spiroamidok …
Clinical comparability of albuterol delivered by the breath-actuated inhaler (Spiros) and albuterol by MDI in patients with asthma.
Geoffroy P, Lalonde RL, Ahrens R, Clarke W, Hill MR, Vaughan LM, Grossman J. Geoffroy P, et al. Ann Allergy Asthma Immunol. 1999 Apr;82(4):377-82. doi: 10.1016/S1081-1206(10)63287-5. Ann Allergy Asthma Immunol. 1999. PMID: 10227336 Clinical Trial.
STUDY OBJECTIVE: This study compares the efficacy and safety of one and two actuations of albuterol sulfate powder delivered via a breath-actuated, effort-assisted, investigational inhaler (Spiros, Dura Pharmaceuticals, Inc) and albuterol delivered via a conventional prope …
STUDY OBJECTIVE: This study compares the efficacy and safety of one and two actuations of albuterol sulfate powder delivered via a breath-ac …
Rolapitant: first global approval.
Syed YY. Syed YY. Drugs. 2015 Nov;75(16):1941-5. doi: 10.1007/s40265-015-0485-8. Drugs. 2015. PMID: 26467681 Review.
An unexpected increase in catheter-associated bloodstream infections at a children's hospital following introduction of the Spiros closed male connector.
Wheeler DS, Giaccone M, Hutchinson N, Haygood M, Demmel K, Britto MT, Margolis PA, Provost LP. Wheeler DS, et al. Am J Infect Control. 2012 Feb;40(1):48-50. doi: 10.1016/j.ajic.2011.02.015. Epub 2011 Jul 22. Am J Infect Control. 2012. PMID: 21782281
An event-cause analysis review showed that 5 of these 9 infections were caused by Staphylococcus aureus. We discovered that the Spiros Closed Male Connector (ICU Medical, San Clemente, CA) had been introduced in these 2 units around the same time as the cluster of infectio …
An event-cause analysis review showed that 5 of these 9 infections were caused by Staphylococcus aureus. We discovered that the Spiros …
Spiropiperidine CCR5 antagonists.
Rotstein DM, Gabriel SD, Makra F, Filonova L, Gleason S, Brotherton-Pleiss C, Setti LQ, Trejo-Martin A, Lee EK, Sankuratri S, Ji C, Derosier A, Dioszegi M, Heilek G, Jekle A, Berry P, Weller P, Mau CI. Rotstein DM, et al. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5401-6. doi: 10.1016/j.bmcl.2009.07.122. Epub 2009 Jul 30. Bioorg Med Chem Lett. 2009. PMID: 19674898
14,460 results
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