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Thromboembolic prevention and anticoagulant therapy during the COVID-19 pandemic: updated clinical guidance from the anticoagulation forum.
Barnes GD, Burnett A, Allen A, Ansell J, Blumenstein M, Clark NP, Crowther M, Dager WE, Deitelzweig SB, Ellsworth S, Garcia D, Kaatz S, Raffini L, Rajasekhar A, Beek AV, Minichiello T. Barnes GD, et al. J Thromb Thrombolysis. 2022 Aug;54(2):197-210. doi: 10.1007/s11239-022-02643-3. Epub 2022 May 17. J Thromb Thrombolysis. 2022. PMID: 35579732 Free PMC article.
Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.
Ton WD, Wang Y, Chai P, Beauchamp-Perez C, Flint NT, Lammers LG, Xiong H, Zhang K, Markus SM. Ton WD, et al. Nat Struct Mol Biol. 2023 Sep;30(9):1365-1379. doi: 10.1038/s41594-023-01010-x. Epub 2023 Jun 15. Nat Struct Mol Biol. 2023. PMID: 37322240
To understand whether and how dynein-LIS1 binding is modulated, we engineered dynein mutants locked in a microtubule-bound (MT-B) or microtubule-unbound (MT-U) state. Whereas the MT-B mutant exhibits low LIS1 affinity, the MT-U mutant binds LIS1 with high affinity, …
To understand whether and how dynein-LIS1 binding is modulated, we engineered dynein mutants locked in a microtubule-bound (MT-B) or …
Interaction of amyloid and tau on cortical microstructure in cognitively unimpaired adults.
Vogt NM, Hunt JFV, Adluru N, Ma Y, Van Hulle CA, Iii DCD, Kecskemeti SR, Chin NA, Carlsson CM, Asthana S, Johnson SC, Kollmorgen G, Batrla R, Wild N, Buck K, Zetterberg H, Alexander AL, Blennow K, Bendlin BB. Vogt NM, et al. Alzheimers Dement. 2022 Jan;18(1):65-76. doi: 10.1002/alz.12364. Epub 2021 May 13. Alzheimers Dement. 2022. PMID: 33984184 Free PMC article.
Myosteatosis is associated with poor physical fitness in patients undergoing hepatopancreatobiliary surgery.
West MA, van Dijk DPJ, Gleadowe F, Reeves T, Primrose JN, Abu Hilal M, Edwards MR, Jack S, Rensen SSS, Grocott MPW, Levett DZH, Olde Damink SWM. West MA, et al. J Cachexia Sarcopenia Muscle. 2019 Aug;10(4):860-871. doi: 10.1002/jcsm.12433. Epub 2019 May 21. J Cachexia Sarcopenia Muscle. 2019. PMID: 31115169 Free PMC article.
In the multivariate analysis, only SM-RA was associated with V O(2) peak (B = 0.25, 95% CI 0.15-0.34, P < 0.001, R(2) = 0.42) and V O(2) at AT (B = 0.13, 95% CI 0.06-0.18, P < 0.001, R(2) = 0.26). ...

In the multivariate analysis, only SM-RA was associated with V O(2) peak (B = 0.25, 95% CI 0.15-0.34, P < 0.001, R(2) = 0.42) and

Benchmarking Outcomes for Molecularly Characterized Synchronous Oligometastatic Non-Small-Cell Lung Cancer Reveals EGFR Mutations to Be Associated With Longer Overall Survival.
De B, Farooqi AS, Mitchell KG, Ludmir EB, Lewis J, Rinsurongkawong W, Rinsurongkawong V, Lee JJ, Swisher SG, Gibbons DL, Zhang J, Le X, Elamin YY, Gomez DR, Ning MS, Lin SH, Liao Z, Chang JY, Vaporciyan AA, Heymach JV, Antonoff MB, Gandhi SJ. De B, et al. JCO Precis Oncol. 2023 Jan;7:e2200540. doi: 10.1200/PO.22.00540. JCO Precis Oncol. 2023. PMID: 36716413 Free PMC article.
Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncology)/Blood and Marrow Transplant Clinical Trial Network 0502.
Devine SM, Owzar K, Blum W, Mulkey F, Stone RM, Hsu JW, Champlin RE, Chen YB, Vij R, Slack J, Soiffer RJ, Larson RA, Shea TC, Hars V, Sibley AB, Giralt S, Carter S, Horowitz MM, Linker C, Alyea EP. Devine SM, et al. J Clin Oncol. 2015 Dec 10;33(35):4167-75. doi: 10.1200/JCO.2015.62.7273. Epub 2015 Nov 2. J Clin Oncol. 2015. PMID: 26527780 Free PMC article. Clinical Trial.