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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 5
2003 2
2004 6
2005 4
2006 4
2007 8
2008 5
2009 8
2010 4
2011 8
2012 7
2013 12
2014 11
2015 9
2016 6
2017 6
2018 4
2019 10
2020 5
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109 results
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Page 1
Targeting Mitochondria for Treatment of Chemoresistant Ovarian Cancer.
Emmings E, Mullany S, Chang Z, Landen CN Jr, Linder S, Bazzaro M. Emmings E, et al. Among authors: linder s. Int J Mol Sci. 2019 Jan 8;20(1):229. doi: 10.3390/ijms20010229. Int J Mol Sci. 2019. PMID: 30626133 Free PMC article. Review.
Inhibition of proteasome deubiquitinating activity as a new cancer therapy.
D'Arcy P, Brnjic S, Olofsson MH, Fryknäs M, Lindsten K, De Cesare M, Perego P, Sadeghi B, Hassan M, Larsson R, Linder S. D'Arcy P, et al. Among authors: linder s. Nat Med. 2011 Nov 6;17(12):1636-40. doi: 10.1038/nm.2536. Nat Med. 2011. PMID: 22057347
Proteasome-associated deubiquitinases and cancer.
Mofers A, Pellegrini P, Linder S, D'Arcy P. Mofers A, et al. Among authors: linder s. Cancer Metastasis Rev. 2017 Dec;36(4):635-653. doi: 10.1007/s10555-017-9697-6. Cancer Metastasis Rev. 2017. PMID: 29134486 Free PMC article. Review.
Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.
Stafford WC, Peng X, Olofsson MH, Zhang X, Luci DK, Lu L, Cheng Q, Trésaugues L, Dexheimer TS, Coussens NP, Augsten M, Ahlzén HM, Orwar O, Östman A, Stone-Elander S, Maloney DJ, Jadhav A, Simeonov A, Linder S, Arnér ESJ. Stafford WC, et al. Among authors: linder s. Sci Transl Med. 2018 Feb 14;10(428):eaaf7444. doi: 10.1126/scitranslmed.aaf7444. Sci Transl Med. 2018. PMID: 29444979 Free PMC article.
Deubiquitinase inhibition as a cancer therapeutic strategy.
D'Arcy P, Wang X, Linder S. D'Arcy P, et al. Among authors: linder s. Pharmacol Ther. 2015 Mar;147:32-54. doi: 10.1016/j.pharmthera.2014.11.002. Epub 2014 Nov 6. Pharmacol Ther. 2015. PMID: 25444757 Free article. Review.
Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug.
Zhang X, Selvaraju K, Saei AA, D'Arcy P, Zubarev RA, Arnér ES, Linder S. Zhang X, et al. Among authors: linder s. Biochimie. 2019 Jul;162:46-54. doi: 10.1016/j.biochi.2019.03.015. Epub 2019 Apr 1. Biochimie. 2019. PMID: 30946948
Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15.
Mofers A, Perego P, Selvaraju K, Gatti L, Gullbo J, Linder S, D'Arcy P. Mofers A, et al. Among authors: linder s. PLoS One. 2019 Oct 22;14(10):e0223807. doi: 10.1371/journal.pone.0223807. eCollection 2019. PLoS One. 2019. PMID: 31639138 Free PMC article.
Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system.
Selvaraju K, Mofers A, Pellegrini P, Salomonsson J, Ahlner A, Morad V, Hillert EK, Espinosa B, Arnér ESJ, Jensen L, Malmström J, Turkina MV, D'Arcy P, Walters MA, Sunnerhagen M, Linder S. Selvaraju K, et al. Among authors: linder s. Sci Rep. 2019 Jul 8;9(1):9841. doi: 10.1038/s41598-019-46168-x. Sci Rep. 2019. PMID: 31285509 Free PMC article.
Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.
Ma R, Karthik GM, Lövrot J, Haglund F, Rosin G, Katchy A, Zhang X, Viberg L, Frisell J, Williams C, Linder S, Fredriksson I, Hartman J. Ma R, et al. Among authors: linder s. J Natl Cancer Inst. 2017 Mar 1;109(3):1-14. doi: 10.1093/jnci/djw236. J Natl Cancer Inst. 2017. PMID: 28376210 Free PMC article.
Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment.
Zhang X, Espinosa B, Saei AA, D'Arcy P, Zubarev RA, Linder S. Zhang X, et al. Among authors: linder s. Oxid Med Cell Longev. 2019 Jun 10;2019:1659468. doi: 10.1155/2019/1659468. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31281566 Free PMC article.
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