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Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.

McMillan EA, Ryu MJ, Diep CH, Mendiratta S, Clemenceau JR, Vaden RM, Kim JH, Motoyaji T, Covington KR, Peyton M, Huffman K, Wu X, Girard L, Sung Y, Chen PH, Mallipeddi PL, Lee JY, Hanson J, Voruganti S, Yu Y, Park S, Sudderth J, DeSevo C, Muzny DM, Doddapaneni H, Gazdar A, Gibbs RA, Hwang TH, Heymach JV, Wistuba I, Coombes KR, Williams NS, Wheeler DA, MacMillan JB, Deberardinis RJ, Roth MG, Posner BA, Minna JD, Kim HS, White MA. McMillan EA, et al. Among authors: voruganti s. Cell. 2018 May 3;173(4):864-878.e29. doi: 10.1016/j.cell.2018.03.028. Epub 2018 Apr 19. Cell. 2018. PMID: 29681454 Free PMC article.

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Tumor-Activated Benzothiazole Inhibitors of Stearoyl-CoA Desaturase.

Williams NS, Gonzales S, Naidoo J, Rivera-Cancel G, Voruganti S, Mallipeddi P, Theodoropoulos PC, Geboers S, Chen H, Ortiz F, Posner B, Nijhawan D, Ready JM. Williams NS, et al. Among authors: voruganti s. J Med Chem. 2020 Sep 10;63(17):9773-9786. doi: 10.1021/acs.jmedchem.0c00899. Epub 2020 Aug 19. J Med Chem. 2020. PMID: 32787093

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Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications.

Wang W, Qin JJ, Voruganti S, Nag S, Zhou J, Zhang R. Wang W, et al. Among authors: voruganti s. Med Res Rev. 2015 Nov;35(6):1220-67. doi: 10.1002/med.21358. Epub 2015 Jul 30. Med Res Rev. 2015. PMID: 26227500 Free PMC article. Review.

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Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair.

Antczak MI, Zhang Y, Wang C, Doran J, Naidoo J, Voruganti S, Williams NS, Markowitz SD, Ready JM. Antczak MI, et al. Among authors: voruganti s. J Med Chem. 2017 May 11;60(9):3979-4001. doi: 10.1021/acs.jmedchem.7b00271. Epub 2017 Apr 25. J Med Chem. 2017. PMID: 28398755 Free PMC article.

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miRNAs in cancer prevention and treatment and as molecular targets for natural product anticancer agents.

Qian B, Nag SA, Su Y, Voruganti S, Qin JJ, Zhang R, Cho WC. Qian B, et al. Among authors: voruganti s. Curr Cancer Drug Targets. 2013 Jun;13(5):519-41. doi: 10.2174/15680096113139990031. Curr Cancer Drug Targets. 2013. PMID: 23597193 Review.

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Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy.

Wang W, Qin JJ, Voruganti S, Nijampatnam B, Velu SE, Ruan KH, Hu M, Zhou J, Zhang R. Wang W, et al. Among authors: voruganti s. Cancer Res. 2018 Oct 1;78(19):5656-5667. doi: 10.1158/0008-5472.CAN-17-3939. Epub 2018 Sep 14. Cancer Res. 2018. PMID: 30217928 Free PMC article.

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Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy.

Qin JJ, Wang W, Sarkar S, Voruganti S, Agarwal R, Zhang R. Qin JJ, et al. Among authors: voruganti s. Oncotarget. 2016 May 31;7(22):32566-78. doi: 10.18632/oncotarget.8873. Oncotarget. 2016. PMID: 27105525 Free PMC article.

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The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models.

Wang W, Qin JJ, Voruganti S, Srivenugopal KS, Nag S, Patil S, Sharma H, Wang MH, Wang H, Buolamwini JK, Zhang R. Wang W, et al. Among authors: voruganti s. Nat Commun. 2014 Oct 1;5:5086. doi: 10.1038/ncomms6086. Nat Commun. 2014. PMID: 25271708 Free PMC article.

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Identification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapy.

Qin JJ, Sarkar S, Voruganti S, Agarwal R, Wang W, Zhang R. Qin JJ, et al. Among authors: voruganti s. J Biomed Res. 2016 Jul;30(4):322-33. doi: 10.7555/JBR.30.20160018. Epub 2016 May 25. J Biomed Res. 2016. PMID: 27533941 Free PMC article.

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Natural product ginsenoside 25-OCH3-PPD inhibits breast cancer growth and metastasis through down-regulating MDM2.

Wang W, Zhang X, Qin JJ, Voruganti S, Nag SA, Wang MH, Wang H, Zhang R. Wang W, et al. Among authors: voruganti s. PLoS One. 2012;7(7):e41586. doi: 10.1371/journal.pone.0041586. Epub 2012 Jul 23. PLoS One. 2012. PMID: 22911819 Free PMC article.

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