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The following term was not found in PubMed: ukhmani
Page 1
Showing results for ukhmani k. Mantel
Search for Sukhmani K. Mantel instead (1 results)
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.
Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM 2nd, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF; Accelerating Medicines Partnership: RA/SLE Network; Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Zhang F, et al. Nature. 2023 Nov;623(7987):616-624. doi: 10.1038/s41586-023-06708-y. Epub 2023 Nov 8. Nature. 2023. PMID: 37938773 Free PMC article.
Granzyme K activates the entire complement cascade.
Donado CA, Theisen E, Zhang F, Nathan A, Fairfield ML, Rupani KV, Jones D, Johannes KP; Accelerating Medicines Partnership RA/SLE Network; Raychaudhuri S, Dwyer DF, Jonsson AH, Brenner MB. Donado CA, et al. Nature. 2025 May;641(8061):211-221. doi: 10.1038/s41586-025-08713-9. Epub 2025 Feb 6. Nature. 2025. PMID: 39914456 Free PMC article.
We previously found that most tissue CD8(+) T cells in rheumatoid arthritis synovium, and in inflamed organs for some other diseases, express granzyme K (GZMK)(2), a tryptase-like protease with poorly defined function. Here, we show that GZMK can activate the complement ca …
We previously found that most tissue CD8(+) T cells in rheumatoid arthritis synovium, and in inflamed organs for some other diseases, expres …
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium.
Dunlap G, Wagner A, Meednu N, Wang R, Zhang F, Ekabe JC, Jonsson AH, Wei K, Sakaue S, Nathan A; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Bykerk VP, Donlin LT, Goodman SM, Firestein GS, Boyle DL, Holers VM, Moreland LW, Tabechian D, Pitzalis C, Filer A, Raychaudhuri S, Brenner MB, Thakar J, McDavid A, Rao DA, Anolik JH. Dunlap G, et al. Nat Commun. 2024 Jun 11;15(1):4991. doi: 10.1038/s41467-024-49186-0. Nat Commun. 2024. PMID: 38862501 Free PMC article.
The clinical use of platelet transfusions: A systematic literature review and meta-analysis on behalf of the International Collaboration for Transfusion Medicine Guidelines.
Jug R, La Rocca U, Al-Riyami AZ, Bathla A, Metcalf RA, White SK, Stanworth SJ, Nahirniak S. Jug R, et al. Transfusion. 2025 Jun;65(6):1155-1169. doi: 10.1111/trf.18277. Epub 2025 May 29. Transfusion. 2025. PMID: 40440162 Free PMC article.
Duplicate screening and data extraction occurred. Meta-analysis used Mantel-Haenszel method of random effects model. RESULTS: Twenty-one RCTs, 24 observational studies, and 20 SRs were included. ...
Duplicate screening and data extraction occurred. Meta-analysis used Mantel-Haenszel method of random effects model. RESULTS: Twenty- …
Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial.
Halton J, Brandão LR, Luciani M, Bomgaars L, Chalmers E, Mitchell LG, Nurmeev I, Sharathkumar A, Svirin P, Gorbatikov K, Tartakovsky I, Simetzberger M, Huang F, Sun Z, Kreuzer J, Gropper S, Reilly P, Brueckmann M, Albisetti M; DIVERSITY Trial Investigators. Halton J, et al. Lancet Haematol. 2021 Jan;8(1):e22-e33. doi: 10.1016/S2352-3026(20)30368-9. Epub 2020 Dec 5. Lancet Haematol. 2021. PMID: 33290737 Clinical Trial.
Standard of care (low-molecular-weight heparins, unfractionated heparin, vitamin K antagonists or fondaparinux) was compared with a paediatric oral dabigatran dosing regimen (an age-adjusted and weight-adjusted nomogram) in children younger than 18 years with acute venous …
Standard of care (low-molecular-weight heparins, unfractionated heparin, vitamin K antagonists or fondaparinux) was compared with a p …
Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial.
Fischer U, Kaesmacher J, Strbian D, Eker O, Cognard C, Plattner PS, Bütikofer L, Mordasini P, Deppeler S, Pereira VM, Albucher JF, Darcourt J, Bourcier R, Benoit G, Papagiannaki C, Ozkul-Wermester O, Sibolt G, Tiainen M, Gory B, Richard S, Liman J, Ernst MS, Boulanger M, Barbier C, Mechtouff L, Zhang L, Marnat G, Sibon I, Nikoubashman O, Reich A, Consoli A, Lapergue B, Ribo M, Tomasello A, Saleme S, Macian F, Moulin S, Pagano P, Saliou G, Carrera E, Janot K, Hernández-Pérez M, Pop R, Schiava LD, Luft AR, Piotin M, Gentric JC, Pikula A, Pfeilschifter W, Arnold M, Siddiqui AH, Froehler MT, Furlan AJ, Chapot R, Wiesmann M, Machi P, Diener HC, Kulcsar Z, Bonati LH, Bassetti CL, Mazighi M, Liebeskind DS, Saver JL, Gralla J; SWIFT DIRECT Collaborators. Fischer U, et al. Lancet. 2022 Jul 9;400(10346):104-115. doi: 10.1016/S0140-6736(22)00537-2. Lancet. 2022. PMID: 35810756 Free article. Clinical Trial.
We assessed the non-inferiority of thrombectomy alone versus intravenous alteplase plus thrombectomy in all randomly assigned and consenting patients using the one-sided lower 95% confidence limit of the Mantel-Haenszel risk difference, with a prespecified non-inferiority …
We assessed the non-inferiority of thrombectomy alone versus intravenous alteplase plus thrombectomy in all randomly assigned and consenting …
Disrupting the RNA polymerase II transcription cycle through CDK7 inhibition ameliorates inflammatory arthritis.
Chen X, Shibu G, Sokolsky BA, Soussana TN, Fisher L, Deochand DK, Dacic M, Mantel I, Ramirez DC, Bell RD, Zhang T, Donlin LT, Goodman SM, Gray NS, Chinenov Y, Fisher RP, Rogatsky I. Chen X, et al. Sci Transl Med. 2024 Nov 20;16(774):eadq5091. doi: 10.1126/scitranslmed.adq5091. Epub 2024 Nov 20. Sci Transl Med. 2024. PMID: 39565872 Free PMC article.
Genetic ablation of a pause-stabilizing negative elongation factor (NELF) in macrophages did not affect baseline Pol II occupancy but enhanced the transcriptional response of paused anti-inflammatory genes to lipopolysaccharide followed by secondary attenuation of inflammatory si …
Genetic ablation of a pause-stabilizing negative elongation factor (NELF) in macrophages did not affect baseline Pol II occupancy but enhanc …
Diagnostic Accuracy of Ultrasonography for Rotator Cuff Tears: A Systematic Review and Meta-analysis.
Farooqi AS, Lee A, Novikov D, Kelly AM, Li X, Kelly JD 4th, Parisien RL. Farooqi AS, et al. Orthop J Sports Med. 2021 Oct 11;9(10):23259671211035106. doi: 10.1177/23259671211035106. eCollection 2021 Oct. Orthop J Sports Med. 2021. PMID: 34660823 Free PMC article. Review.
The mean difference and 95% confidence interval were calculated for both US and MRI diagnostic values, and meta-analysis was conducted using the Mantel-Haenszel random-effects model. RESULTS: In total, 23 eligible studies involving 2054 shoulders were included. ...
The mean difference and 95% confidence interval were calculated for both US and MRI diagnostic values, and meta-analysis was conducted using …
Efficacy and Safety of DaxibotulinumtoxinA for Injection in Cervical Dystonia: ASPEN-1 Phase 3 Randomized Controlled Trial.
Comella CL, Jankovic J, Hauser RA, Patel AT, Banach MD, Ehler E, Vitarella D, Rubio RG, Gross TM; ASPEN-1 Study Group. Comella CL, et al. Neurology. 2024 Feb 27;102(4):e208091. doi: 10.1212/WNL.0000000000208091. Epub 2024 Jan 31. Neurology. 2024. PMID: 38295339 Free PMC article. Clinical Trial.
Multiplicity-adjusted intent-to-treat hypothesis tests with multiple imputation were performed using ANCOVA and Cochran-Mantel-Haenszel analyses. RESULTS: Of 444 individuals screened, 301 were randomized to DAXI 125U (n = 125) or 250U (n = 130) or placebo (n = 46). ...
Multiplicity-adjusted intent-to-treat hypothesis tests with multiple imputation were performed using ANCOVA and Cochran-Mantel-Haensz …
SPP1hi macrophages in fibrin niches promote hyperplastic tissue remodeling in rheumatoid arthritis synovium.
Mantel I, Zhang H, Vargas J, Ce G, Townsend H, Bell R, Lakhanpal A, Fein MR; Accelerating Medicines Partnership: RA/SLE Network; Norman TM, Orange DE, Ramirez DC, DiCarlo EF, Goodman SM, Smith MH, Zhang F, Wei K, Dey KK, Rudensky AY, Leslie CS, Donlin LT. Mantel I, et al. Sci Transl Med. 2026 Jun 24;18(855):eaed3087. doi: 10.1126/scitranslmed.aed3087. Epub 2026 Jun 24. Sci Transl Med. 2026. PMID: 42341080 Free PMC article.
256 results