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Levodopa Added to Stroke Rehabilitation: The ESTREL Randomized Clinical Trial.
Engelter ST, Kaufmann JE, Zietz A, Luft AR, Polymeris A, Altersberger VL, Wiesner K, Wiegert M, Held JPO, Rottenberger Y, Schwarz A, Medlin F, Accolla EA, Foucras S, Kägi G, De Marchis GM, Politz S, Greulich M, Tarnutzer AA, Sturzenegger R, Katan M, Fischer U, Nedeltchev K, Schär J, Van Den Keybus Deglon K, Rapin PA, Salerno A, Seiffge DJ, Auer E, Lippert J, Bonati LH, Schuster-Amft C, Gäumann S, Chabwine JN, Humm A, Möller JC, Schweinfurther R, Bujan B, Jedrysiak P, Sandor PS, Gonzenbach R, Mylius V, Lutz D, Lienert C, Peters N, Michel P, Müri RM, Schädelin S, Hemkens LG, Ford GA, Lyrer PA, Gensicke H, Traenka C; ESTREL Investigators. Engelter ST, et al. JAMA. 2025 Nov 4;334(17):1523-1532. doi: 10.1001/jama.2025.15185. JAMA. 2025. PMID: 40982270 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: A double-blind, placebo-controlled randomized clinical trial at 13 stroke units and centers and 11 collaborating rehabilitation centers in Switzerland. ...CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, among patients …
DESIGN, SETTING, AND PARTICIPANTS: A double-blind, placebo-controlled randomized clinical trial at 13 stroke units and centers and 11 …
Intracranial Hemorrhage in Patients With Stroke After Endovascular Treatment With or Without IV Alteplase: An Individual Participant Data Meta-Analysis.
Zhou Y, Zhang L, Cavalcante F, Suzuki K, Treurniet KM, Yan B, Mitchell P, Bush S, Fischer U, Kaesmacher J, Gralla J, Strbian D, Rohner R, Kappelhof M, Roos Y, Majoie C, Zi W, Yang Q, Zhang Y, Matsumaru Y, Kimura K, Ye X, Yang P, Liu J; IRIS collaborators. Zhou Y, et al. JAMA Neurol. 2025 Oct 1;82(10):1031-1039. doi: 10.1001/jamaneurol.2025.2610. JAMA Neurol. 2025. PMID: 40788598
DATA SOURCES: PubMed and MEDLINE were searched from database inception through March 9, 2023. STUDY SELECTION: Randomized clinical trials comparing EVT alone with IVT plus EVT for anterior circulation large vessel occlusion stroke were included. ...
DATA SOURCES: PubMed and MEDLINE were searched from database inception through March 9, 2023. STUDY SELECTION: Randomized clinical tr …
Impact of thrombectomy techniques on outcome in medium or distal vessel occlusion: subanalysis of the DISTAL Trial.
Schulze-Zachau V, Rommers N, Dobrocky T, Hajdu SD, Fiehler J, Fragata I, Gralla J, Machi P, Kirschke JS, van Es ACGM, Kaesmacher J, Buhk JH, Saver JL, Martínez-Galdámez M, Piechowiak EII, Kaiser DPO, Tancredi I, Van Den Bergh F, Hellstern V, Khanafer A, Volders D, Strbian D, Ribo M, Karwacki GM, Aebischer V, Brehm A, Fischer U, Psychogios MN, Collaborators D. Schulze-Zachau V, et al. J Neurointerv Surg. 2025 Dec 3:jnis-2025-024374. doi: 10.1136/jnis-2025-024374. Online ahead of print. J Neurointerv Surg. 2025. PMID: 41339078