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Page 1
Showing results for aichi amino
Search for Taichi Umino instead (2 results)
Tantalum-Catalyzed Amidation of Amino Acid Homologues.
Muramatsu W, Yamamoto H. Muramatsu W, et al. J Am Chem Soc. 2019 Dec 4;141(48):18926-18931. doi: 10.1021/jacs.9b08415. Epub 2019 Nov 19. J Am Chem Soc. 2019. PMID: 31730340
A tantalum-catalyzed solvent-free approach for the construction of amide bonds with 1-(trimethylsilyl)imidazole is developed, and the mild reaction conditions are applicable to a wide variety of electrophilic amino acid homologues. This approach delivers a new class of pep …
A tantalum-catalyzed solvent-free approach for the construction of amide bonds with 1-(trimethylsilyl)imidazole is developed, and the mild r …
Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes.
Takahara T, Amemiya Y, Sugiyama R, Maki M, Shibata H. Takahara T, et al. J Biomed Sci. 2020 Aug 17;27(1):87. doi: 10.1186/s12929-020-00679-2. J Biomed Sci. 2020. PMID: 32799865 Free PMC article. Review.
The activity of mTORC1 is dynamically regulated by several environmental cues, including amino acid availability, growth factors, energy levels, and stresses, to coordinate cellular status with environmental conditions. ...In this review, we discuss the mechanisms of regul …
The activity of mTORC1 is dynamically regulated by several environmental cues, including amino acid availability, growth factors, ene …
Trimethylaluminum-mediated one-pot peptide elongation.
Hattori T, Yamamoto H. Hattori T, et al. Chem Sci. 2023 Apr 27;14(21):5795-5801. doi: 10.1039/d3sc00208j. eCollection 2023 May 31. Chem Sci. 2023. PMID: 37265739 Free PMC article.
Efficient and straightforward peptide bond formation of N-, and C-terminal unprotected amino acids was successfully achieved by using trimethylaluminum. The coupling reaction was accomplished by pre-reaction of N-, and C-terminal unprotected amino acids and trimethy …
Efficient and straightforward peptide bond formation of N-, and C-terminal unprotected amino acids was successfully achieved by using …
Tolerable amounts of amino acids for human supplementation: summary and lessons from published peer-reviewed studies.
Blachier F, Blais A, Elango R, Saito K, Shimomura Y, Kadowaki M, Matsumoto H. Blachier F, et al. Amino Acids. 2021 Sep;53(9):1313-1328. doi: 10.1007/s00726-021-03054-z. Epub 2021 Aug 2. Amino Acids. 2021. PMID: 34338884 Free PMC article. Review.
Amino acid supplementation may be indicated to correct for insufficient amino acid intake in healthy individuals, and in specific physiological or pathophysiological situations. ...From the calculations made, it appears that for these 9 amino acids, the calcu …
Amino acid supplementation may be indicated to correct for insufficient amino acid intake in healthy individuals, and in speci …
Relationships between Slc1a5 and Osteoclastogenesis.
Tsumura H, Shindo M, Ito M, Igarashi A, Takeda K, Matsumoto K, Ohkura T, Miyado K, Sugiyama F, Umezawa A, Ito Y. Tsumura H, et al. Comp Med. 2021 Aug 1;71(4):285-294. doi: 10.30802/AALAS-CM-21-000012. Epub 2021 Jun 28. Comp Med. 2021. PMID: 34301346 Free PMC article.
Slc1a5 (ASCT2) encodes a small neutral amino-acid exchanger and is the most well-studied glutamine transporter in cancer cells. ...
Slc1a5 (ASCT2) encodes a small neutral amino-acid exchanger and is the most well-studied glutamine transporter in cancer cells. ...
[Acquired hypoalbuminemia].
Kato H, Takamoto S. Kato H, et al. Ryoikibetsu Shokogun Shirizu. 1998;(22 Pt 3):565-8. Ryoikibetsu Shokogun Shirizu. 1998. PMID: 9851219 Review. Japanese. No abstract available.
[Guanine deaminase].
Yoshino M, Murakami K. Yoshino M, et al. Nihon Rinsho. 2003 Jan;61 Suppl 1:95-7. Nihon Rinsho. 2003. PMID: 12629698 Review. Japanese. No abstract available.
Substrate-Directed Lewis-Acid Catalysis for Peptide Synthesis.
Muramatsu W, Hattori T, Yamamoto H. Muramatsu W, et al. J Am Chem Soc. 2019 Aug 7;141(31):12288-12295. doi: 10.1021/jacs.9b03850. Epub 2019 Jul 26. J Am Chem Soc. 2019. PMID: 31309835
The presented method has the following advantages: (1) the high-yielding peptide synthesis uses a tantalum catalyst for any amino acids; (2) the reaction proceeds without any racemization; (3) the new substrate-directed chemical ligation using the titanium catalyst is appl …
The presented method has the following advantages: (1) the high-yielding peptide synthesis uses a tantalum catalyst for any amino aci …
Peptide Bond Formation Between Unprotected Amino Acids: Convergent Synthesis of Oligopeptides.
Hattori T, Yamamoto H. Hattori T, et al. J Am Chem Soc. 2024 Sep 18;146(37):25738-25744. doi: 10.1021/jacs.4c08049. Epub 2024 Sep 4. J Am Chem Soc. 2024. PMID: 39229861
In the history of peptide chemical synthesis, amino acid-protecting groups have become basic, essential, and common moieties. As the use of protecting groups for amino acids effectively suppresses unwanted side reactions and enables the desired reaction to proceed s …
In the history of peptide chemical synthesis, amino acid-protecting groups have become basic, essential, and common moieties. As the …
2,371 results