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Human blood concentrations of cotinine, a biomonitoring marker for tobacco smoke, extrapolated from nicotine metabolism in rats and humans and physiologically based pharmacokinetic modeling.
Yamazaki H, Horiuchi K, Takano R, Nagano T, Shimizu M, Kitajima M, Murayama N, Shono F. Yamazaki H, et al. Among authors: nagano t. Int J Environ Res Public Health. 2010 Sep;7(9):3406-21. doi: 10.3390/ijerph7093406. Epub 2010 Sep 1. Int J Environ Res Public Health. 2010. PMID: 20948932 Free PMC article.