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The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies.

Pötter R, Tanderup K, Kirisits C, de Leeuw A, Kirchheiner K, Nout R, Tan LT, Haie-Meder C, Mahantshetty U, Segedin B, Hoskin P, Bruheim K, Rai B, Huang F, Van Limbergen E, Schmid M, Nesvacil N, Sturdza A, Fokdal L, Jensen NBK, Georg D, Assenholt M, Seppenwoolde Y, Nomden C, Fortin I, Chopra S, van der Heide U, Rumpold T, Lindegaard JC, Jürgenliemk-Schulz I; EMBRACE Collaborative Group. Pötter R, et al. Among authors: Tan LT. Clin Transl Radiat Oncol. 2018 Jan 11;9:48-60. doi: 10.1016/j.ctro.2018.01.001. eCollection 2018 Feb. Clin Transl Radiat Oncol. 2018. PMID: 29594251 Free PMC article. Review.

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2

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.

Wu D, Hu D, Chen H, Shi G, Fetahu IS, Wu F, Rabidou K, Fang R, Tan L, Xu S, Liu H, Argueta C, Zhang L, Mao F, Yan G, Chen J, Dong Z, Lv R, Xu Y, Wang M, Ye Y, Zhang S, Duquette D, Geng S, Yin C, Lian CG, Murphy GF, Adler GK, Garg R, Lynch L, Yang P, Li Y, Lan F, Fan J, Shi Y, Shi YG. Wu D, et al. Among authors: Tan L, Li Y. Nature. 2018 Jul;559(7715):637-641. doi: 10.1038/s41586-018-0350-5. Epub 2018 Jul 18. Nature. 2018. PMID: 30022161 Free PMC article.

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3

Zc3h13 Regulates Nuclear RNA m⁶A Methylation and Mouse Embryonic Stem Cell Self-Renewal.

Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, Shi YG, He C, Shi Y, Diao J. Wen J, et al. Among authors: Tan L. Mol Cell. 2018 Mar 15;69(6):1028-1038.e6. doi: 10.1016/j.molcel.2018.02.015. Mol Cell. 2018. PMID: 29547716 Free PMC article.

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4

A Review of Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer.

Li Y, Wang J, Ma X, Tan L, Yan Y, Xue C, Hui B, Liu R, Ma H, Ren J. Li Y, et al. Among authors: Tan L. Int J Biol Sci. 2016 Jul 17;12(8):1022-31. doi: 10.7150/ijbs.15438. eCollection 2016. Int J Biol Sci. 2016. PMID: 27489505 Free PMC article. Review.

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5

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader.

Huang HT, Dobrovolsky D, Paulk J, Yang G, Weisberg EL, Doctor ZM, Buckley DL, Cho JH, Ko E, Jang J, Shi K, Choi HG, Griffin JD, Li Y, Treon SP, Fischer ES, Bradner JE, Tan L, Gray NS. Huang HT, et al. Among authors: Li Y, Tan L. Cell Chem Biol. 2018 Jan 18;25(1):88-99.e6. doi: 10.1016/j.chembiol.2017.10.005. Epub 2017 Nov 9. Cell Chem Biol. 2018. PMID: 29129717 Free PMC article.

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6

Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK).

Powell CE, Gao Y, Tan L, Donovan KA, Nowak RP, Loehr A, Bahcall M, Fischer ES, Jänne PA, George RE, Gray NS. Powell CE, et al. Among authors: Tan L. J Med Chem. 2018 May 10;61(9):4249-4255. doi: 10.1021/acs.jmedchem.7b01655. Epub 2018 Apr 24. J Med Chem. 2018. PMID: 29660984 Free PMC article.

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7

Biological Functions and Molecular Mechanisms of Antibiotic Tigecycline in the Treatment of Cancers.

Dong Z, Abbas MN, Kausar S, Yang J, Li L, Tan L, Cui H. Dong Z, et al. Among authors: Li L, Tan L. Int J Mol Sci. 2019 Jul 22;20(14):3577. doi: 10.3390/ijms20143577. Int J Mol Sci. 2019. PMID: 31336613 Free PMC article. Review.

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8

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.

Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC Jr, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG. Lian CG, et al. Among authors: Tan L. Cell. 2012 Sep 14;150(6):1135-46. doi: 10.1016/j.cell.2012.07.033. Cell. 2012. PMID: 22980977 Free PMC article.

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9

Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.

Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Tan L, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, Westover KD, Sorger PK, Gray NS. Rao S, et al. Among authors: Tan L. Cell Chem Biol. 2019 Jun 20;26(6):818-829.e9. doi: 10.1016/j.chembiol.2019.02.021. Epub 2019 Apr 11. Cell Chem Biol. 2019. PMID: 30982749

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10

A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi.

Rosas-Diaz T, Zhang D, Fan P, Wang L, Ding X, Jiang Y, Jimenez-Gongora T, Medina-Puche L, Zhao X, Feng Z, Zhang G, Liu X, Bejarano ER, Tan L, Zhang H, Zhu JK, Xing W, Faulkner C, Nagawa S, Lozano-Duran R. Rosas-Diaz T, et al. Among authors: Tan L. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1388-1393. doi: 10.1073/pnas.1715556115. Epub 2018 Jan 23. Proc Natl Acad Sci U S A. 2018. PMID: 29363594 Free PMC article.

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