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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 5
2008 8
2009 4
2010 6
2011 6
2012 11
2013 15
2014 16
2015 4
2016 5
2017 4
2018 2
2019 3
2020 3
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78 results
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Page 1
Structural basis for allosteric PARP-1 retention on DNA breaks.
Zandarashvili L, Langelier MF, Velagapudi UK, Hancock MA, Steffen JD, Billur R, Hannan ZM, Wicks AJ, Krastev DB, Pettitt SJ, Lord CJ, Talele TT, Pascal JM, Black BE. Zandarashvili L, et al. Among authors: Talele TT. Science. 2020 Apr 3;368(6486):eaax6367. doi: 10.1126/science.aax6367. Science. 2020. PMID: 32241924
Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity.
Velagapudi UK, Langelier MF, Delgado-Martin C, Diolaiti ME, Bakker S, Ashworth A, Patel BA, Shao X, Pascal JM, Talele TT. Velagapudi UK, et al. Among authors: Talele TT. J Med Chem. 2019 Jun 13;62(11):5330-5357. doi: 10.1021/acs.jmedchem.8b01709. Epub 2019 May 24. J Med Chem. 2019. PMID: 31042381
Acetylene Group, Friend or Foe in Medicinal Chemistry.
Talele TT. Talele TT. J Med Chem. 2020 Feb 19. doi: 10.1021/acs.jmedchem.9b01617. Online ahead of print. J Med Chem. 2020. PMID: 32031378
Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein.
Patel BA, Abel B, Barbuti AM, Velagapudi UK, Chen ZS, Ambudkar SV, Talele TT. Patel BA, et al. Among authors: Talele TT. J Med Chem. 2018 Feb 8;61(3):834-864. doi: 10.1021/acs.jmedchem.7b01340. Epub 2018 Jan 23. J Med Chem. 2018. PMID: 29251928 Free PMC article.
Revisiting prochirality.
Ochs RS, Talele TT. Ochs RS, et al. Among authors: Talele TT. Biochimie. 2020 Mar;170:65-72. doi: 10.1016/j.biochi.2019.12.009. Epub 2019 Dec 17. Biochimie. 2020. PMID: 31862235
Chemical Space Exploration around Thieno[3,2-d]pyrimidin-4(3H)-one Scaffold Led to a Novel Class of Highly Active Clostridium difficile Inhibitors.
Shao X, AbdelKhalek A, Abutaleb NS, Velagapudi UK, Yoganathan S, Seleem MN, Talele TT. Shao X, et al. Among authors: Talele TT. J Med Chem. 2019 Nov 14;62(21):9772-9791. doi: 10.1021/acs.jmedchem.9b01198. Epub 2019 Oct 21. J Med Chem. 2019. PMID: 31584822
Discovery of conjugated thiazolidinone-thiadiazole scaffold as anti-dengue virus polymerase inhibitors.
Manvar D, Küçükgüzel İ, Erensoy G, Tatar E, Deryabaşoğulları G, Reddy H, Talele TT, Cevik O, Kaushik-Basu N. Manvar D, et al. Among authors: Talele TT. Biochem Biophys Res Commun. 2016 Jan 15;469(3):743-7. doi: 10.1016/j.bbrc.2015.12.042. Epub 2015 Dec 15. Biochem Biophys Res Commun. 2016. PMID: 26697747
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