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Showing results for manner carlisle
Search for Tanner Carlisle instead (1 results)
Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease.
O'Donoghue ML, Rosenson RS, Gencer B, López JAG, Lepor NE, Baum SJ, Stout E, Gaudet D, Knusel B, Kuder JF, Ran X, Murphy SA, Wang H, Wu Y, Kassahun H, Sabatine MS; OCEAN(a)-DOSE Trial Investigators. O'Donoghue ML, et al. N Engl J Med. 2022 Nov 17;387(20):1855-1864. doi: 10.1056/NEJMoa2211023. Epub 2022 Nov 6. N Engl J Med. 2022. PMID: 36342163 Free article. Clinical Trial.
At 36 weeks, the lipoprotein(a) concentration had increased by a mean of 3.6% in the placebo group, whereas olpasiran therapy had significantly and substantially reduced the lipoprotein(a) concentration in a dose-dependent manner, resulting in placebo-adjusted mean percent …
At 36 weeks, the lipoprotein(a) concentration had increased by a mean of 3.6% in the placebo group, whereas olpasiran therapy had significan …
The New European Medical Device Regulation: Balancing Innovation and Patient Safety.
Bretthauer M, Gerke S, Hassan C, Ahmad OF, Mori Y. Bretthauer M, et al. Ann Intern Med. 2023 Jun;176(6):844-848. doi: 10.7326/M23-0454. Epub 2023 Apr 18. Ann Intern Med. 2023. PMID: 37068279 Review.
Enhanced collaborations between the medical device industry and physician partners will be needed to meet the new requirements in a timely manner to avoid shortages of existing devices and to mitigate barriers to development of new devices....
Enhanced collaborations between the medical device industry and physician partners will be needed to meet the new requirements in a timely …
Short-course neoadjuvant in situ vaccination for murine melanoma.
Aiken TJ, Komjathy D, Rodriguez M, Stuckwisch A, Feils A, Subbotin V, Birstler J, Gillies SD, Rakhmilevich AL, Erbe AK, Sondel PM. Aiken TJ, et al. J Immunother Cancer. 2022 Jan;10(1):e003586. doi: 10.1136/jitc-2021-003586. J Immunother Cancer. 2022. PMID: 35039460 Free PMC article.
Neoadjuvant IT-IC and resection resulted in the rejection of B16 lung metastasis in a CD4 T cell dependent manner. CONCLUSIONS: Neoadjuvant IT-IC generates immunologic memory capable of preventing distant metastasis despite limited efficacy against large primary melanoma t …
Neoadjuvant IT-IC and resection resulted in the rejection of B16 lung metastasis in a CD4 T cell dependent manner. CONCLUSIONS: Neoad …
Indicators of the effects of climate change on freshwater ecosystems.
Rose KC, Bierwagen B, Bridgham SD, Carlisle DM, Hawkins CP, Poff NL, Read JS, Rohr J, Saros JE, Williamson CE. Rose KC, et al. Clim Change. 2023 Mar 1;173(23):1-20. doi: 10.1007/s10584-022-03457-1. Clim Change. 2023. PMID: 39022649 Free PMC article.
The responses of any given freshwater ecosystem to climate change depend on the magnitude of climate forcing, interactions with other anthropogenic and natural changes, and the characteristics of the ecosystem itself. Therefore, the magnitude and manner in which freshwater …
The responses of any given freshwater ecosystem to climate change depend on the magnitude of climate forcing, interactions with other anthro …
Revisiting the FAITH Trial: A Secondary Analysis Yielding Novel Insights with the Win Ratio.
Bzovsky S, O'Hara NN, Slobogean GP, Sprague S, Axelrod DE, Hoit G, Pannozzo K, Bhandari M, Swiontkowski M, Schemitsch E, Poolman RW; FAITH Investigators. Bzovsky S, et al. JB JS Open Access. 2025 Nov 25;10(4):e25.00230. doi: 10.2106/JBJS.OA.25.00230. eCollection 2025 Oct-Dec. JB JS Open Access. 2025. PMID: 41281368 Free PMC article.
We assessed outcomes hierarchically using the win ratio method, comparing each patient with every other patient in the alternative treatment group in a pairwise manner. We conducted sensitivity analyses at 6 and 12 months, and subgroup analyses to explore smoking status an …
We assessed outcomes hierarchically using the win ratio method, comparing each patient with every other patient in the alternative treatment …
Sexual selection and pseudogenization in primate fertilization.
Carlisle JA, Bickell AL, Hart MW. Carlisle JA, et al. Evolution. 2025 Sep 12;79(8):1670-1680. doi: 10.1093/evolut/qpaf072. Evolution. 2025. PMID: 40472076 Free PMC article.
The mouse sperm protein ZP3R interacts with proteins in the egg coat and mediates sperm-egg adhesion in a species-specific manner. Understanding the function and evolution of such genes has important implications for studies of speciation, reproductive success, and inferti …
The mouse sperm protein ZP3R interacts with proteins in the egg coat and mediates sperm-egg adhesion in a species-specific manner. Un …
Permissive hypoxaemia versus normoxaemia for mechanically ventilated critically ill patients.
Gilbert-Kawai ET, Mitchell K, Martin D, Carlisle J, Grocott MP. Gilbert-Kawai ET, et al. Cochrane Database Syst Rev. 2014 May 7;2014(5):CD009931. doi: 10.1002/14651858.CD009931.pub2. Cochrane Database Syst Rev. 2014. PMID: 24801519 Free PMC article.
Exact values defining 'conventional' and 'permissive hypoxaemia' groupings were purposely not specified, and the manner in which these oxygenation goals were achieved also was not specified. We did state however that the intervention group required a target oxygenation lev …
Exact values defining 'conventional' and 'permissive hypoxaemia' groupings were purposely not specified, and the manner in which thes …
Recurrent Duplication and Diversification of Acrosomal Fertilization Proteins in Abalone.
Carlisle JA, Glenski MA, Swanson WJ. Carlisle JA, et al. Front Cell Dev Biol. 2022 Apr 7;10:795273. doi: 10.3389/fcell.2022.795273. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35465314 Free PMC article.
Despite clade-specific acrosomal protein paralogs, there are no concomitant duplications of egg coat proteins in H. tuberculata, indicating that duplication of egg proteins per se is not responsible for retention of duplicated acrosomal proteins. We hypothesize that, in a mann …
Despite clade-specific acrosomal protein paralogs, there are no concomitant duplications of egg coat proteins in H. tuberculata, indicating …
Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity.
Byun JH, Lebeau PF, Platko K, Carlisle RE, Faiyaz M, Chen J, MacDonald ME, Makda Y, Yousof T, Lynn EG, Dickhout JG, Krepinsky JC, Weaver F, Igdoura SA, Seidah NG, Austin RC. Byun JH, et al. Kidney360. 2022 Apr 27;3(8):1394-1410. doi: 10.34067/KID.0007022021. eCollection 2022 Aug 25. Kidney360. 2022. PMID: 36176646 Free PMC article.
CONCLUSIONS: We report that circulating PCSK9 modulates renal lipid uptake in a manner dependent on renal CD36. In the context of increased dietary fat consumption, the absence of circulating PCSK9 may promote renal lipid accumulation and subsequent renal injury. ...
CONCLUSIONS: We report that circulating PCSK9 modulates renal lipid uptake in a manner dependent on renal CD36. In the context of inc …
Mechanism of effective combination radio-immunotherapy against 9464D-GD2, an immunologically cold murine neuroblastoma.
Aiken TJ, Erbe AK, Zebertavage L, Komjathy D, Feils AS, Rodriguez M, Stuckwisch A, Gillies SD, Morris ZS, Birstler J, Rakhmilevich AL, Sondel PM. Aiken TJ, et al. J Immunother Cancer. 2022 May;10(5):e004834. doi: 10.1136/jitc-2022-004834. J Immunother Cancer. 2022. PMID: 35618290 Free PMC article.
CONCLUSION: Treatment with CAIR cures 9464D-GD2 tumors in a NK cell dependent manner and induction of MHC-I by tumors cells was associated with decreased efficacy. These results demonstrate that the early tumor response to this regimen is T and NK cell independent, but tha …
CONCLUSION: Treatment with CAIR cures 9464D-GD2 tumors in a NK cell dependent manner and induction of MHC-I by tumors cells was assoc …
37 results