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Page 1
A metabolic dependency of EBV can be targeted to hinder B cell transformation.
Müller-Durovic B, Jäger J, Engelmann C, Schuhmachers P, Altermatt S, Schlup Y, Duthaler U, Makowiec C, Unterstab G, Roffeis S, Xhafa E, Assmann N, Trulsson F, Steiner R, Edwards-Hicks J, West J, Turner L, Develioglu L, Ivanek R, Azzi T, Dehio P, Berger C; Swiss Transplant Cohort Study; Kuzmin D, Saboz S, Mautner J, Löliger J, Geigges M, Palianina D, Khanna N, Dirnhofer S, Münz C, Bantug GR, Hess C. Müller-Durovic B, et al. Among authors: azzi t. Science. 2024 Jul 5;385(6704):eadk4898. doi: 10.1126/science.adk4898. Epub 2024 Jul 5. Science. 2024. PMID: 38781354
Innate immune responses against Epstein Barr virus infection.
Chijioke O, Azzi T, Nadal D, Münz C. Chijioke O, et al. Among authors: azzi t. J Leukoc Biol. 2013 Dec;94(6):1185-90. doi: 10.1189/jlb.0313173. Epub 2013 Jun 28. J Leukoc Biol. 2013. PMID: 23812328 Free PMC article. Review.
Reduced frequency of cytotoxic CD56dim CD16+ NK cells leads to impaired antibody-dependent degranulation in EBV-positive classical Hodgkin lymphoma.
Pánisová E, Lünemann A, Bürgler S, Kotur M, Lazarovici J, Danu A, Kaulfuss M, Mietz J, Chijioke O, Münz C, Busson P, Berger C, Ghez D, Azzi T. Pánisová E, et al. Among authors: azzi t. Cancer Immunol Immunother. 2022 Jan;71(1):13-24. doi: 10.1007/s00262-021-02956-x. Epub 2021 May 15. Cancer Immunol Immunother. 2022. PMID: 33993319 Free PMC article.
Immunosuppressive FK506 treatment leads to more frequent EBV-associated lymphoproliferative disease in humanized mice.
Caduff N, McHugh D, Murer A, Rämer P, Raykova A, Landtwing V, Rieble L, Keller CW, Prummer M, Hoffmann L, Lam JKP, Chiang AKS, Raulf F, Azzi T, Berger C, Rubic-Schneider T, Traggiai E, Lünemann JD, Kammüller M, Münz C. Caduff N, et al. Among authors: azzi t. PLoS Pathog. 2020 Apr 6;16(4):e1008477. doi: 10.1371/journal.ppat.1008477. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32251475 Free PMC article.
Correction: Immunosuppressive FK506 treatment leads to more frequent EBV-associated lymphoproliferative disease in humanized mice.
Caduff N, McHugh D, Murer A, Rämer P, Raykova A, Landtwing V, Rieble L, Keller CW, Prummer M, Hoffmann L, Lam JKP, Chiang AKS, Raulf F, Azzi T, Berger C, Rubic-Schneider T, Traggiai E, Lünemann JD, Kammüller M, Münz C. Caduff N, et al. Among authors: azzi t. PLoS Pathog. 2020 Dec 21;16(12):e1009167. doi: 10.1371/journal.ppat.1009167. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33347498 Free PMC article.
CD4 + T cells are found within endemic Burkitt lymphoma and modulate Burkitt lymphoma precursor cell viability and expression of pathogenically relevant Epstein-Barr virus genes.
Sidorov S, Fux L, Steiner K, Bounlom S, Traxel S, Azzi T, Berisha A, Berger C, Bernasconi M, Niggli FK, Perner Y, Pather S, Kempf W, Nadal D, Bürgler S. Sidorov S, et al. Among authors: azzi t. Cancer Immunol Immunother. 2022 Jun;71(6):1371-1392. doi: 10.1007/s00262-021-03057-5. Epub 2021 Oct 19. Cancer Immunol Immunother. 2022. PMID: 34668039 Free PMC article.
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