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Year Number of Results
2018 1
2019 1
2020 2
2021 1
2022 0
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5 results
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Page 1
PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells.
Kauko O, O'Connor CM, Kulesskiy E, Sangodkar J, Aakula A, Izadmehr S, Yetukuri L, Yadav B, Padzik A, Laajala TD, Haapaniemi P, Momeny M, Varila T, Ohlmeyer M, Aittokallio T, Wennerberg K, Narla G, Westermarck J. Kauko O, et al. Among authors: varila t. Sci Transl Med. 2018 Jul 18;10(450):eaaq1093. doi: 10.1126/scitranslmed.aaq1093. Sci Transl Med. 2018. PMID: 30021885 Free PMC article.
Nebulisers as a potential source of airborne virus.
Tang JW, Kalliomaki P, Varila TM, Waris M, Koskela H. Tang JW, et al. Among authors: varila tm. J Infect. 2020 Oct;81(4):647-679. doi: 10.1016/j.jinf.2020.05.025. Epub 2020 May 15. J Infect. 2020. PMID: 32422151 Free PMC article. No abstract available.
Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1.
Kauko O, Imanishi SY, Kulesskiy E, Yetukuri L, Laajala TD, Sharma M, Pavic K, Aakula A, Rupp C, Jumppanen M, Haapaniemi P, Ruan L, Yadav B, Suni V, Varila T, Corthals GL, Reimand J, Wennerberg K, Aittokallio T, Westermarck J. Kauko O, et al. Among authors: varila t. J Biol Chem. 2020 Mar 27;295(13):4194-4211. doi: 10.1074/jbc.RA119.011265. Epub 2020 Feb 18. J Biol Chem. 2020. PMID: 32071079 Free PMC article.
Discovery of a Novel CIP2A Variant (NOCIVA) with Clinical Relevance in Predicting TKI Resistance in Myeloid Leukemias.
Mäkelä E, Pavic K, Varila T, Salmenniemi U, Löyttyniemi E, Nagelli SG, Ammunét T, Kähäri VM, Clark RE, Elo LL, Bachanaboyina VK, Lucas CM, Itälä-Remes M, Westermarck J. Mäkelä E, et al. Among authors: varila t. Clin Cancer Res. 2021 May 15;27(10):2848-2860. doi: 10.1158/1078-0432.CCR-20-3679. Epub 2021 Mar 5. Clin Cancer Res. 2021. PMID: 33674272 Free article.