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Page 1
A quantitative map of nuclear pore assembly reveals two distinct mechanisms.
Otsuka S, Tempkin JOB, Zhang W, Politi AZ, Rybina A, Hossain MJ, Kueblbeck M, Callegari A, Koch B, Morero NR, Sali A, Ellenberg J. Otsuka S, et al. Among authors: tempkin job. Nature. 2023 Jan;613(7944):575-581. doi: 10.1038/s41586-022-05528-w. Epub 2023 Jan 4. Nature. 2023. PMID: 36599981 Free PMC article.
Dynamic molecular mechanism of the nuclear pore complex permeability barrier.
Kozai T, Fernandez-Martinez J, van Eeuwen T, Gallardo P, Kapinos LE, Mazur A, Zhang W, Tempkin J, Panatala R, Delgado-Izquierdo M, Raveh B, Sali A, Chait BT, Veenhoff LM, Rout MP, Lim RYH. Kozai T, et al. Among authors: tempkin j. bioRxiv [Preprint]. 2023 Apr 14:2023.03.31.535055. doi: 10.1101/2023.03.31.535055. bioRxiv. 2023. PMID: 37066338 Free PMC article. Preprint.
Bayesian metamodeling of complex biological systems across varying representations.
Raveh B, Sun L, White KL, Sanyal T, Tempkin J, Zheng D, Bharath K, Singla J, Wang C, Zhao J, Li A, Graham NA, Kesselman C, Stevens RC, Sali A. Raveh B, et al. Among authors: tempkin j. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2104559118. doi: 10.1073/pnas.2104559118. Proc Natl Acad Sci U S A. 2021. PMID: 34453000 Free PMC article.
Generating Protein Structures for Pathway Discovery Using Deep Learning.
Georgouli K, Stephany RR, Tempkin JOB, Santiago C, Aydin F, Heimann MA, Pottier L, Zhang X, Carpenter TS, Hsu T, Nissley DV, Streitz FH, Lightstone FC, Ingolfsson HI, Bremer PT. Georgouli K, et al. Among authors: tempkin job. J Chem Theory Comput. 2024 Oct 22;20(20):8795-8806. doi: 10.1021/acs.jctc.4c00816. Epub 2024 Oct 10. J Chem Theory Comput. 2024. PMID: 39388723 Free PMC article.
Nucleotide regulation of the structure and dynamics of G-actin.
Saunders MG, Tempkin J, Weare J, Dinner AR, Roux B, Voth GA. Saunders MG, et al. Among authors: tempkin j. Biophys J. 2014 Apr 15;106(8):1710-20. doi: 10.1016/j.bpj.2014.03.012. Biophys J. 2014. PMID: 24739170 Free PMC article.
Integrative spatiotemporal modeling of biomolecular processes: application to the assembly of the Nuclear Pore Complex.
Latham AP, Tempkin JOB, Otsuka S, Zhang W, Ellenberg J, Sali A. Latham AP, et al. Among authors: tempkin job. bioRxiv [Preprint]. 2024 Aug 8:2024.08.06.606842. doi: 10.1101/2024.08.06.606842. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2025 Mar 18;122(11):e2415674122. doi: 10.1073/pnas.2415674122. PMID: 39149317 Free PMC article. Updated. Preprint.
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