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Year Number of Results
2014 2
2015 5
2016 2
2017 2
2018 2
2019 6
2020 7
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De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder.
Calpena E, Hervieu A, Kaserer T, Swagemakers SMA, Goos JAC, Popoola O, Ortiz-Ruiz MJ, Barbaro-Dieber T, Bownass L, Brilstra EH, Brimble E, Foulds N, Grebe TA, Harder AVE, Lees MM, Monaghan KG, Newbury-Ecob RA, Ong KR, Osio D, Reynoso Santos FJ, Ruzhnikov MRZ, Telegrafi A, van Binsbergen E, van Dooren MF; Deciphering Developmental Disorders Study, van der Spek PJ, Blagg J, Twigg SRF, Mathijssen IMJ, Clarke PA, Wilkie AOM. Calpena E, et al. Among authors: kaserer t. Am J Hum Genet. 2019 Apr 4;104(4):709-720. doi: 10.1016/j.ajhg.2019.02.006. Epub 2019 Mar 21. Am J Hum Genet. 2019. PMID: 30905399 Free PMC article.
Modulating FOXO3 transcriptional activity by small, DBD-binding molecules.
Hagenbuchner J, Obsilova V, Kaserer T, Kaiser N, Rass B, Psenakova K, Docekal V, Alblova M, Kohoutova K, Schuster D, Aneichyk T, Vesely J, Obexer P, Obsil T, Ausserlechner MJ. Hagenbuchner J, et al. Among authors: kaserer t. Elife. 2019 Dec 4;8:e48876. doi: 10.7554/eLife.48876. Elife. 2019. PMID: 31789593 Free PMC article.
A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma.
Salcher S, Spoden G, Hagenbuchner J, Führer S, Kaserer T, Tollinger M, Huber-Cantonati P, Gruber T, Schuster D, Gust R, Zwierzina H, Müller T, Kiechl-Kohlendorfer U, Ausserlechner MJ, Obexer P. Salcher S, et al. Among authors: kaserer t. Oncogene. 2020 Jan;39(5):1080-1097. doi: 10.1038/s41388-019-1044-7. Epub 2019 Oct 7. Oncogene. 2020. PMID: 31591479 Free PMC article.
Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics.
Weston M, Kaserer T, Wu A, Mouravlev A, Carpenter JC, Snowball A, Knauss S, von Schimmelmann M, During MJ, Lignani G, Schorge S, Young D, Kullmann DM, Lieb A. Weston M, et al. Among authors: kaserer t. Sci Adv. 2019 Apr 17;5(4):eaaw1567. doi: 10.1126/sciadv.aaw1567. eCollection 2019 Apr. Sci Adv. 2019. PMID: 31001591 Free PMC article.
Steroid sulfatase inhibiting lanostane triterpenes - Structure activity relationship and in silico insights.
Grienke U, Kaserer T, Kirchweger B, Lambrinidis G, Kandel RT, Foster PA, Schuster D, Mikros E, Rollinger JM. Grienke U, et al. Among authors: kaserer t. Bioorg Chem. 2020 Jan;95:103495. doi: 10.1016/j.bioorg.2019.103495. Epub 2019 Dec 9. Bioorg Chem. 2020. PMID: 31855822
Virtual screening applications in short-chain dehydrogenase/reductase research.
Beck KR, Kaserer T, Schuster D, Odermatt A. Beck KR, et al. Among authors: kaserer t. J Steroid Biochem Mol Biol. 2017 Jul;171:157-177. doi: 10.1016/j.jsbmb.2017.03.008. Epub 2017 Mar 9. J Steroid Biochem Mol Biol. 2017. PMID: 28286207 Free PMC article. Review.
Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase.
Akram M, Patt M, Kaserer T, Temml V, Waratchareeyakul W, Kratschmar DV, Haupenthal J, Hartmann RW, Odermatt A, Schuster D. Akram M, et al. Among authors: kaserer t. J Steroid Biochem Mol Biol. 2019 Sep;192:105358. doi: 10.1016/j.jsbmb.2019.04.007. Epub 2019 Apr 6. J Steroid Biochem Mol Biol. 2019. PMID: 30965118
Evaluation of APOBEC3B Recognition Motifs by NMR Reveals Preferred Substrates.
Liu M, Mallinger A, Tortorici M, Newbatt Y, Richards M, Mirza A, van Montfort RLM, Burke R, Blagg J, Kaserer T. Liu M, et al. Among authors: kaserer t. ACS Chem Biol. 2018 Sep 21;13(9):2427-2432. doi: 10.1021/acschembio.8b00639. Epub 2018 Aug 27. ACS Chem Biol. 2018. PMID: 30130388 Free PMC article.
Combining Mutational Signatures, Clonal Fitness, and Drug Affinity to Define Drug-Specific Resistance Mutations in Cancer.
Kaserer T, Blagg J. Kaserer T, et al. Cell Chem Biol. 2018 Nov 15;25(11):1359-1371.e2. doi: 10.1016/j.chembiol.2018.07.013. Epub 2018 Aug 23. Cell Chem Biol. 2018. PMID: 30146241 Free PMC article.
Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases.
Kaserer T, Beck KR, Akram M, Odermatt A, Schuster D. Kaserer T, et al. Molecules. 2015 Dec 19;20(12):22799-832. doi: 10.3390/molecules201219880. Molecules. 2015. PMID: 26703541 Free PMC article. Review.
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