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Page 1
Discovery of novel 2-[(4-hydroxy-6-oxo-2,3-dihydro-1H-pyridine-5-carbonyl)amino]acetic acid derivatives as HIF prolyl hydroxylase inhibitors for treatment of renal anemia.
Hamada M, Takayama T, Shibata T, Hiratate A, Takahashi M, Yashiro M, Takayama N, Okumura-Kitajima L, Koretsune H, Kajiyama H, Naruse T, Kato S, Takano H, Kakinuma H. Hamada M, et al. Among authors: takayama t. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1725-1730. doi: 10.1016/j.bmcl.2018.04.039. Epub 2018 Apr 16. Bioorg Med Chem Lett. 2018. PMID: 29681433
5-(1,3-Benzothiazol-6-yl)-4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazole derivatives as potent and selective transforming growth factor-β type I receptor inhibitors.
Amada H, Sekiguchi Y, Ono N, Koami T, Takayama T, Yabuuchi T, Katakai H, Ikeda A, Aoki M, Naruse T, Wada R, Nozoe A, Sato M. Amada H, et al. Among authors: takayama t. Bioorg Med Chem. 2012 Dec 15;20(24):7128-38. doi: 10.1016/j.bmc.2012.09.066. Epub 2012 Oct 12. Bioorg Med Chem. 2012. PMID: 23117174
23 results