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2016 2
2019 3
2020 1
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Page 1
Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases.
Krajnc A, Brem J, Hinchliffe P, Calvopiña K, Panduwawala TD, Lang PA, Kamps JJAG, Tyrrell JM, Widlake E, Saward BG, Walsh TR, Spencer J, Schofield CJ. Krajnc A, et al. Among authors: panduwawala td. J Med Chem. 2019 Sep 26;62(18):8544-8556. doi: 10.1021/acs.jmedchem.9b00911. Epub 2019 Sep 16. J Med Chem. 2019. PMID: 31454231 Free PMC article.
Will morphing boron-based inhibitors beat the β-lactamases?
Krajnc A, Lang PA, Panduwawala TD, Brem J, Schofield CJ. Krajnc A, et al. Among authors: panduwawala td. Curr Opin Chem Biol. 2019 Jun;50:101-110. doi: 10.1016/j.cbpa.2019.03.001. Epub 2019 Apr 18. Curr Opin Chem Biol. 2019. PMID: 31004962 Free PMC article. Review.
Functionalised bicyclic tetramates derived from cysteine as antibacterial agents.
Panduwawala TD, Iqbal S, Thompson AL, Genov M, Pretsch A, Pretsch D, Liu S, Ebright RH, Howells A, Maxwell A, Moloney MG. Panduwawala TD, et al. Org Biomol Chem. 2019 Jun 5;17(22):5615-5632. doi: 10.1039/c9ob01076a. Org Biomol Chem. 2019. PMID: 31120090 Free PMC article.
Scalar Cross-Relaxation Detected in the NOESY Spectra of Oxazolidines and Thiazolidines.
Panduwawala TD, Josa-Culleré L, Kuprov I, Odell B, Moloney MG, Claridge TD. Panduwawala TD, et al. J Org Chem. 2016 May 20;81(10):4142-8. doi: 10.1021/acs.joc.6b00458. Epub 2016 May 11. J Org Chem. 2016. PMID: 27148796
Chemoselectivity and stereoselectivity of cyclisation pathways leading to bicyclic tetramates controlled by ring-chain tautomerisation in thiazolidines.
Panduwawala TD, Iqbal S, Tirfoin R, Moloney MG. Panduwawala TD, et al. Org Biomol Chem. 2016 May 11;14(19):4464-78. doi: 10.1039/c6ob00557h. Org Biomol Chem. 2016. PMID: 27089842
Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli.
Lang PA, Parkova A, Leissing TM, Calvopiña K, Cain R, Krajnc A, Panduwawala TD, Philippe J, Fishwick CWG, Trapencieris P, Page MGP, Schofield CJ, Brem J. Lang PA, et al. Among authors: panduwawala td. Biomolecules. 2020 Jun 12;10(6):899. doi: 10.3390/biom10060899. Biomolecules. 2020. PMID: 32545682 Free PMC article.