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Inclusion complex between β-cyclodextrin and hecogenin acetate produces superior analgesic effect in animal models for orofacial pain.
Carvalho YMBG, Menezes PP, Sousa BMH, Lima BS, Trindade IAS, Serafini MR, Pereira EWM, Rezende MM, Quintans JSS, Quintans-Júnior LJ, Nakamura CV, Silva-Júnior EF, Crispim AC, Aquino TM, Araújo AAS. Carvalho YMBG, et al. Biomed Pharmacother. 2017 Sep;93:754-762. doi: 10.1016/j.biopha.2017.06.091. Epub 2017 Jul 10. Biomed Pharmacother. 2017. PMID: 28704800
Therefore, in an attempt to overcome this, we set out to create inclusion complexes between HA and b-cyclodextrin (b-CD) and evaluate the antinociceptive effects in the orofacial nociception in mice. ...The results of the physicochemical characterization elucidated …
Therefore, in an attempt to overcome this, we set out to create inclusion complexes between HA and b-cyclodextrin (b-CD) and e …
Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi.
Silva-Júnior EF, Silva EPS, França PHB, Silva JPN, Barreto EO, Silva EB, Ferreira RS, Gatto CC, Moreira DRM, Siqueira-Neto JL, Mendonça-Júnior FJB, Lima MCA, Bortoluzzi JH, Scotti MT, Scotti L, Meneghetti MR, Aquino TM, Araújo-Júnior JX. Silva-Júnior EF, et al. Bioorg Med Chem. 2016 Sep 15;24(18):4228-4240. doi: 10.1016/j.bmc.2016.07.013. Epub 2016 Jul 20. Bioorg Med Chem. 2016. PMID: 27475533 Free article.
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