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Page 1
Inhibition of mitophagy drives macrophage activation and antibacterial defense during sepsis.
Patoli D, Mignotte F, Deckert V, Dusuel A, Dumont A, Rieu A, Jalil A, Van Dongen K, Bourgeois T, Gautier T, Magnani C, Le Guern N, Mandard S, Bastin J, Djouadi F, Schaeffer C, Guillaumot N, Narce M, Nguyen M, Guy J, Dargent A, Quenot JP, Rialland M, Masson D, Auwerx J, Lagrost L, Thomas C. Patoli D, et al. Among authors: bourgeois t. J Clin Invest. 2020 Nov 2;130(11):5858-5874. doi: 10.1172/JCI130996. J Clin Invest. 2020. PMID: 32759503 Free PMC article.
Impaired unsaturated fatty acid elongation alters mitochondrial function and accelerates metabolic dysfunction-associated steatohepatitis progression.
Vouilloz A, Bourgeois T, Diedisheim M, Pilot T, Jalil A, Le Guern N, Bergas V, Rohmer N, Castelli F, Leleu D, Varin A, de Barros JP, Degrace P, Rialland M, Blériot C, Venteclef N, Thomas C, Masson D. Vouilloz A, et al. Among authors: bourgeois t. Metabolism. 2025 Jan;162:156051. doi: 10.1016/j.metabol.2024.156051. Epub 2024 Oct 23. Metabolism. 2025. PMID: 39454822 Free article.
LPCAT3 deficiency in hematopoietic cells alters cholesterol and phospholipid homeostasis and promotes atherosclerosis.
Thomas C, Jalil A, Magnani C, Ishibashi M, Queré R, Bourgeois T, Bergas V, Ménégaut L, Patoli D, Le Guern N, Labbé J, Gautier T, de Barros JPP, Lagrost L, Masson D. Thomas C, et al. Among authors: bourgeois t. Atherosclerosis. 2018 Aug;275:409-418. doi: 10.1016/j.atherosclerosis.2018.05.023. Epub 2018 May 18. Atherosclerosis. 2018. PMID: 29866392
Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet.
Bourgeois T, Jalil A, Thomas C, Magnani C, Le Guern N, Gautier T, Pais de Barros JP, Bergas V, Choubley H, Mazzeo L, Menegaut L, Josiane Lebrun L, Van Dongen K, Xolin M, Jourdan T, Buch C, Labbé J, Saas P, Lagrost L, Masson D, Grober J. Bourgeois T, et al. J Lipid Res. 2021;62:100013. doi: 10.1194/jlr.RA120000737. Epub 2020 Dec 17. J Lipid Res. 2021. PMID: 33518513 Free PMC article.
Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion.
Lebrun LJ, Lenaerts K, Kiers D, Pais de Barros JP, Le Guern N, Plesnik J, Thomas C, Bourgeois T, Dejong CHC, Kox M, Hundscheid IHR, Khan NA, Mandard S, Deckert V, Pickkers P, Drucker DJ, Lagrost L, Grober J. Lebrun LJ, et al. Among authors: bourgeois t. Cell Rep. 2017 Oct 31;21(5):1160-1168. doi: 10.1016/j.celrep.2017.10.008. Cell Rep. 2017. PMID: 29091756 Free article.
Plasmalogen remodeling modulates macrophage response to cytotoxic oxysterols and atherosclerotic plaque vulnerability.
Jalil A, Pilot T, Bourgeois T, Laubriet A, Li X, Diedisheim M, Deckert V, Magnani C, Le Guern N, Pais de Barros JP, Nguyen M, Pallot G, Vouilloz A, Proukhnitzky L, Hermetet F, Aires V, Lesniewska E, Lagrost L, Auwerx J, Le Goff W, Venteclef N, Steinmetz E, Thomas C, Masson D. Jalil A, et al. Among authors: bourgeois t. Cell Rep Med. 2025 May 6:102131. doi: 10.1016/j.xcrm.2025.102131. Online ahead of print. Cell Rep Med. 2025. PMID: 40345182 Free article.