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Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel.
Teleshova N, Keller MJ, Fernández Romero JA, Friedland BA, Creasy GW, Plagianos MG, Ray L, Barnable P, Kizima L, Rodriguez A, Cornejal N, Melo C, Cruz Rodriguez G, Mukhopadhyay S, Calenda G, Sinkar SU, Bonnaire T, Wesenberg A, Zhang S, Kleinbeck K, Palmer K, Alami M, O'Keefe BR, Gillevet P, Hur H, Liang Y, Santone G, Fichorova RN, Kalir T, Zydowsky TM. Teleshova N, et al. Among authors: bonnaire t. PLoS One. 2022 Jan 20;17(1):e0261775. doi: 10.1371/journal.pone.0261775. eCollection 2022. PLoS One. 2022. PMID: 35051209 Free PMC article. Clinical Trial.
Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus.
Levendosky K, Mizenina O, Martinelli E, Jean-Pierre N, Kizima L, Rodriguez A, Kleinbeck K, Bonnaire T, Robbiani M, Zydowsky TM, O'Keefe BR, Fernández-Romero JA. Levendosky K, et al. Among authors: bonnaire t. Antimicrob Agents Chemother. 2015 Dec;59(12):7290-8. doi: 10.1128/AAC.01816-15. Epub 2015 Sep 14. Antimicrob Agents Chemother. 2015. PMID: 26369967 Free PMC article.
MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model.
Barnable P, Calenda G, Bonnaire T, Menon R, Levendosky K, Gettie A, Blanchard J, Cooney ML, Fernández-Romero JA, Zydowsky TM, Teleshova N. Barnable P, et al. Among authors: bonnaire t. Antimicrob Agents Chemother. 2015 Jul;59(7):3829-37. doi: 10.1128/AAC.00073-15. Epub 2015 Apr 13. Antimicrob Agents Chemother. 2015. PMID: 25870063 Free PMC article.