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Assessment of machine perfusion conditions for the donation after circulatory death heart preservation.
Cholyway R, Akande O, Mauro AG, Mezzaroma E, Wang R, Kenning K, Toldo S, Quader M. Cholyway R, et al. Artif Organs. 2022 Jul;46(7):1346-1357. doi: 10.1111/aor.14208. Epub 2022 Feb 22. Artif Organs. 2022. PMID: 35167122 Free PMC article.
METHODS: To achieve this, rat hearts were procured following a DCD or control beating-heart donation (CBD) model, and perfused for 60 min with one of three machine perfusion solutions-St. Thomas (ST), University of Wisconsin (UW), or Polyethylene Glycol-20k (PEG)-at …
METHODS: To achieve this, rat hearts were procured following a DCD or control beating-heart donation (CBD) model, and perfused for 60 min wi …
Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality [Internet].
Henderson JT, Vesco KK, Senger CA, Thomas RG, Redmond N. Henderson JT, et al. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Sep. Report No.: 21-05274-EF-1. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Sep. Report No.: 21-05274-EF-1. PMID: 34644040 Free Books & Documents. Review.
Connexin 43 Regulates Intercellular Mitochondrial Transfer from Human Mesenchymal Stromal Cells to Chondrocytes.
Irwin RM, Thomas MA, Fahey MJ, Mayán MD, Smyth JW, Delco ML. Irwin RM, et al. bioRxiv [Preprint]. 2024 Mar 20:2024.03.18.585552. doi: 10.1101/2024.03.18.585552. bioRxiv. 2024. PMID: 38562828 Free PMC article. Preprint.
MSC Cx43 expression was knocked down using siRNA or overexpressed (GJA1+ and GJA1-20k+) using lentiviral transduction. Chondrocytes and MSCs were co-cultured for 24 hrs in direct contact or separated using transwells. ...CONCLUSIONS: Overexpression of GJA1-20k in MS …
MSC Cx43 expression was knocked down using siRNA or overexpressed (GJA1+ and GJA1-20k+) using lentiviral transduction. Chondrocytes a …
Preoperative comprehensive geriatric assessment and optimisation prior to elective arterial vascular surgery: a health economic analysis.
Partridge JSL, Healey A, Modarai B, Harari D, Martin FC, Dhesi JK. Partridge JSL, et al. Age Ageing. 2021 Sep 11;50(5):1770-1777. doi: 10.1093/ageing/afab094. Age Ageing. 2021. PMID: 34120179
An incremental net benefit of 0.58 QALYs at a cost-effectiveness threshold of 30k, 0.60 QALYs at a threshold of 20k and 0.63 QALYs at a threshold of 13k was observed. Mean total pre- and postoperative health care utilisation costs were estimated to be 1,165 lower for CGA p …
An incremental net benefit of 0.58 QALYs at a cost-effectiveness threshold of 30k, 0.60 QALYs at a threshold of 20k and 0.63 QALYs at …
Identifying probable dementia in undiagnosed Black and White Americans using machine learning in Veterans Health Administration electronic health records.
Shao Y, Todd K, Shutes-David A, Millard SP, Brown K, Thomas A, Chen K, Wilson K, Zeng QT, Tsuang DW. Shao Y, et al. medRxiv [Preprint]. 2023 Feb 14:2023.02.08.23285540. doi: 10.1101/2023.02.08.23285540. medRxiv. 2023. PMID: 36798376 Free PMC article. Preprint.
Scores were validated via blinded manual chart reviews (n=1.2K) of controls from a separate sample (n=20K). AUCs and negative and positive predictive values (NPVs and PPVs) were calculated to evaluate the models. ...
Scores were validated via blinded manual chart reviews (n=1.2K) of controls from a separate sample (n=20K). AUCs and negative and pos …
Population-based assessment of cancer survivors' financial burden and quality of life: a prospective cohort study.
Zafar SY, McNeil RB, Thomas CM, Lathan CS, Ayanian JZ, Provenzale D. Zafar SY, et al. J Oncol Pract. 2015 Mar;11(2):145-50. doi: 10.1200/JOP.2014.001542. Epub 2014 Dec 16. J Oncol Pract. 2015. PMID: 25515717 Free PMC article.
High financial burden was associated with lower household income (adjusted odds ratio [OR] = 0.61 per $20k per year, P < .001) and younger age (adjusted OR = 0.63 per 10 years; P < .001). ...

High financial burden was associated with lower household income (adjusted odds ratio [OR] = 0.61 per $20k per year, P < .001) and

Effect of interferon-alpha-2b on the enhancement of tumour uptake of 99Tcm-labelled monoclonal antibodies.
Li J, Duggaraju R, Maish DR, Thakur ML. Li J, et al. Nucl Med Commun. 1996 Apr;17(4):346-52. doi: 10.1097/00006231-199604000-00163. Nucl Med Commun. 1996. PMID: 8786872
The maximum increase (from 2.0 +/- 1.4% in the control group to 7.2 +/- 1.2% in the experimental group, P < 0.01) was obtained when 20K international units of IFN-alpha-2b were injected intramuscularly....

The maximum increase (from 2.0 +/- 1.4% in the control group to 7.2 +/- 1.2% in the experimental group, P < 0.01) was obtained when 20