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96 results
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Page 1
Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease.
Zhou Y, Zhong NS, Li X, Chen S, Zheng J, Zhao D, Yao W, Zhi R, Wei L, He B, Zhang X, Yang C, Li Y, Li F, Du J, Gui J, Hu B, Bai C, Huang P, Chen G, Xu Y, Wang C, Liang B, Li Y, Hu G, Tan H, Ye X, Ma X, Chen Y, Hu X, Tian J, Zhu X, Shi Z, Du X, Li M, Liu S, Yu R, Zhao J, Ma Q, Xie C, Li X, Chen T, Lin Y, Zeng L, Ye C, Ye W, Luo X, Zeng L, Yu S, Guan WJ, Ran P. Zhou Y, et al. N Engl J Med. 2017 Sep 7;377(10):923-935. doi: 10.1056/NEJMoa1700228. N Engl J Med. 2017. PMID: 28877027 Free article. Clinical Trial.
CONCLUSIONS: Tiotropium resulted in a higher FEV(1) than placebo at 24 months and ameliorated the annual decline in the FEV(1) after bronchodilator use in patients with COPD of GOLD stage 1 or 2. (Funded by Boehringer Ingelheim and others; Tie-COPD ClinicalTrials.gov numbe …
CONCLUSIONS: Tiotropium resulted in a higher FEV(1) than placebo at 24 months and ameliorated the annual decline in the FEV(1) after broncho …
Glycation of Tie-2 Inhibits Angiopoietin-1 Signaling Activation and Angiopoietin-1-Induced Angiogenesis.
Zhou H, Chen T, Li Y, You J, Deng X, Chen N, Li T, Zheng Y, Li R, Luo M, Wu J, Wang L. Zhou H, et al. Int J Mol Sci. 2022 Jun 27;23(13):7137. doi: 10.3390/ijms23137137. Int J Mol Sci. 2022. PMID: 35806141 Free PMC article.
Furthermore, MGO treatment markedly increased AGE cross-linking of Tie-2 in cultured aortae ex vivo and MGO-induced Tie-2 glycation also significantly decreased Ang-1-induced vessel outgrow from aortic rings. Collectively, these data suggest that Tie-2 may be …
Furthermore, MGO treatment markedly increased AGE cross-linking of Tie-2 in cultured aortae ex vivo and MGO-induced Tie-2 glyc …
Luo Tong Formula Alleviates Diabetic Retinopathy in Rats Through Micro-200b Target.
Pang B, Ni Q, Di S, Du LJ, Qin YL, Li QW, Li M, Tong XL. Pang B, et al. Front Pharmacol. 2020 Oct 30;11:551766. doi: 10.3389/fphar.2020.551766. eCollection 2020. Front Pharmacol. 2020. PMID: 33324202 Free PMC article.
Aim: Diabetic retinopathy (DR) is a serious complication of diabetes (DM). Luo Tong formula (LTF) exerts protective effects against DR in rats, but its underlying mechanism remains unknown. ...Results: DM rats exhibits significantly increased blood retinal-barrier (BRB) br …
Aim: Diabetic retinopathy (DR) is a serious complication of diabetes (DM). Luo Tong formula (LTF) exerts protective effects against D …
Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease.
Liu J, Nair V, Zhao YY, Chang DY, Limonte C, Bansal N, Fermin D, Eichinger F, Tanner EC, Bellovich KA, Steigerwalt S, Bhat Z, Hawkins JJ, Subramanian L, Rosas SE, Sedor JR, Vasquez MA, Waikar SS, Bitzer M, Pennathur S, Brosius FC, De Boer I, Chen M, Kretzler M, Ju W; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group. Liu J, et al. Diabetes. 2022 Dec 1;71(12):2664-2676. doi: 10.2337/db22-0169. Diabetes. 2022. PMID: 36331122 Free PMC article.
One marker, plasma angiopoietin 2 (ANGPT2), was significantly associated with outcomes in cohorts from the Cardiovascular Health Study (N = 3,183) and the Chinese Cohort Study of Chronic Kidney Disease (N = 210). Glomerular transcriptional angiopoietin/Tie (ANG-TIE) …
One marker, plasma angiopoietin 2 (ANGPT2), was significantly associated with outcomes in cohorts from the Cardiovascular Health Study (N = …
Prevalence and risk factors of active tuberculosis in patients with rheumatic diseases: a multi-center, cross-sectional study in China.
Liu X, Zhang L, Zhang F, Zeng X, Zhao Y, Wang Q, Liu S, Zuo X, Zhang Z, Wu H, Chen S, Li H, Zhu P, Wu L, Qi W, Liu Y, Zhang M, Liu H, Xu D, Zheng W, Zhang Y, Shi X, Han L, Zhou Y, Zhao Y, Wang W, Li T, Tie N, Zhang K, Luo C, Gong B, Zhao Y, Lv C, Song L, Wu Q, Fei Y, Zhang L, Luo H, Sun J, Xue J, Gu L, Wang J, Han Q, Yimaity K, Zhou J, Zhao L, Bian S, Qi W, Li Y, Zhu Y, Han H, Liao S, Liu G. Liu X, et al. Emerg Microbes Infect. 2021 Dec;10(1):2303-2312. doi: 10.1080/22221751.2021.2004864. Emerg Microbes Infect. 2021. PMID: 34753408 Free PMC article.
Expression of Angiopoietin-1 and the receptor Tie-2 mRNA in rat brains following intracerebral hemorrhage.
Zhou H, Tang T, Guo C, Zhang H, Zhong J, Zheng J, Luo J, Lin Y, Liu W, Luo W, Yang Q. Zhou H, et al. Acta Neurobiol Exp (Wars). 2008;68(2):147-54. Acta Neurobiol Exp (Wars). 2008. PMID: 18511951 Free article.
RT-PCR analysis showed that Ang-1 and Tie-2 mRNA signal was detected at 2 days and persisted for 28 days after ICH. These findings suggest that ICH could lead to upregulation of Ang-1 and the receptor Tie-2 mRNA....
RT-PCR analysis showed that Ang-1 and Tie-2 mRNA signal was detected at 2 days and persisted for 28 days after ICH. These findings su …
Lymphadenectomy Around Inferior Mesenteric Artery in Low-Tie vs High-Tie Laparoscopic Anterior Resection: Short- and Long-Term Outcome of a Cohort of 614 Rectal Cancers.
Luo Y, Yu MH, Huang YZ, Jing R, Qin J, Qin SL, Shah JN, Zhong M. Luo Y, et al. Cancer Manag Res. 2021 May 14;13:3963-3971. doi: 10.2147/CMAR.S282986. eCollection 2021. Cancer Manag Res. 2021. PMID: 34017199 Free PMC article.
BACKGROUND: Preservation of the left colic artery in low-tie (LT) of inferior mesenteric artery remains controversial compared to high-tie (HT) in the colon and rectal cancers, for lymph node dissection, anastomotic leakage, and oncological outcome. ...
BACKGROUND: Preservation of the left colic artery in low-tie (LT) of inferior mesenteric artery remains controversial compared to hig …
Immunotherapy of tumors with protein vaccine based on chicken homologous Tie-2.
Luo Y, Wen YJ, Ding ZY, Fu CH, Wu Y, Liu JY, Li Q, He QM, Zhao X, Jiang Y, Li J, Deng HX, Kang B, Mao YQ, Wei YQ. Luo Y, et al. Clin Cancer Res. 2006 Mar 15;12(6):1813-9. doi: 10.1158/1078-0432.CCR-05-1990. Clin Cancer Res. 2006. PMID: 16551866
PURPOSE: Tie-2 is an endothelium-specific receptor tyrosine kinase known to play a key role in tumor angiogenesis. The present study explores the feasibility of immunotherapy of tumors by using a protein vaccine based on chicken Tie-2 as a model antigen to break the …
PURPOSE: Tie-2 is an endothelium-specific receptor tyrosine kinase known to play a key role in tumor angiogenesis. The present study …
96 results