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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1963 1
1964 4
1965 1
1966 2
1967 2
1968 1
1969 1
1971 1
1973 2
1974 5
1975 2
1976 4
1977 10
1978 6
1979 10
1980 5
1981 4
1982 5
1983 4
1984 3
1985 3
1986 5
1987 7
1988 32
1989 56
1990 20
1991 18
1992 20
1993 21
1994 26
1995 31
1996 59
1997 77
1998 110
1999 121
2000 156
2001 154
2002 200
2003 210
2004 262
2005 265
2006 300
2007 344
2008 374
2009 357
2010 405
2011 508
2012 474
2013 530
2014 593
2015 815
2016 883
2017 913
2018 997
2019 1040
2020 1147
2021 1230
2022 91
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11,565 results
Results by year
Filters applied: . Clear all The following term was not found in PubMed: Pertzel
Page 1
Did you mean tim reitzel (3 results)?
Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-kappaB/TNF-alpha pathway.
Yang H, Xie T, Li D, Du X, Wang T, Li C, Song X, Xu L, Yi F, Liang X, Gao L, Yang X, Ma C. Yang H, et al. Mol Metab. 2019 May;23:24-36. doi: 10.1016/j.molmet.2019.02.007. Epub 2019 Feb 26. Mol Metab. 2019. PMID: 30862474 Free PMC article.
METHODS: We downregulated Tim-3 expression in kidney (intrarenal injection of Tim-3 shRNA expressing lentivirus or global Tim-3 knockout mice) and induced DN by streptozotocin (STZ). ...Similar effects were observed in mice with Tim-3 knockdown diabeti …
METHODS: We downregulated Tim-3 expression in kidney (intrarenal injection of Tim-3 shRNA expressing lentivirus or global T
TIM-4 interference in Kupffer cells against CCL4-induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway.
Wu H, Chen G, Wang J, Deng M, Yuan F, Gong J. Wu H, et al. Cell Prolif. 2020 Jan;53(1):e12731. doi: 10.1111/cpr.12731. Epub 2019 Nov 22. Cell Prolif. 2020. PMID: 31755616 Free PMC article.
However, the role of TIM-4 expressed by Kupffer cells (KCs) in liver fibrosis remains unclear. ...TIM-4 interference essentially contributed to liver fibrosis resolution. ...
However, the role of TIM-4 expressed by Kupffer cells (KCs) in liver fibrosis remains unclear. ...TIM-4 interference essential …
Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.
Zhang W, Zhang Y, He Y, Wang X, Fang Q. Zhang W, et al. Exp Cell Res. 2019 Mar 15;376(2):124-132. doi: 10.1016/j.yexcr.2019.02.007. Epub 2019 Feb 11. Exp Cell Res. 2019. PMID: 30763585
However, the effects of Tim-3/Gal-9 signalling on M1/M2 macrophage polarization are unclear. ...M1/M2 phenotypic macrophage markers were measured 0, 1, 3, 6, 12, and 24 h after stimulation, alpha-lactose was used to inhibit Gal-9, anti-mouse Tim-3 antibody was used …
However, the effects of Tim-3/Gal-9 signalling on M1/M2 macrophage polarization are unclear. ...M1/M2 phenotypic macrophage markers w …
Comprehensive Analysis of the Expression, Relationship to Immune Infiltration and Prognosis of TIM-1 in Cancer.
Kong X, Fu M, Niu X, Jiang H. Kong X, et al. Front Oncol. 2020 Sep 4;10:1086. doi: 10.3389/fonc.2020.01086. eCollection 2020. Front Oncol. 2020. PMID: 33014768 Free PMC article.
TIM-1 is a critical gene that regulates T-helper cell development. However, little research has revealed the distribution, prognosis, and immune infiltration of TIM-1 in cancers. TCGA, GEO, Oncomine, TIMER, Kaplan-Meier, PrognoScan, GEPIA, TISIDB, and HPA databases
TIM-1 is a critical gene that regulates T-helper cell development. However, little research has revealed the distribution, prognosis,
IL-6 promotes metastasis of non-small-cell lung cancer by up-regulating TIM-4 via NF-kappaB.
Liu W, Wang H, Bai F, Ding L, Huang Y, Lu C, Chen S, Li C, Yue X, Liang X, Ma C, Xu L, Gao L. Liu W, et al. Cell Prolif. 2020 Mar;53(3):e12776. doi: 10.1111/cpr.12776. Epub 2020 Feb 5. Cell Prolif. 2020. PMID: 32020709 Free PMC article.
Both TIM-4 and IL-6 promoted migration, invasion and EMT of NSCLC cells. Interestingly, TIM-4 knockdown reversed the role of IL-6 in NSCLC and IL-6 promoted metastasis of NSCLC by up-regulating TIM-4 via NF-kappaB. ...
Both TIM-4 and IL-6 promoted migration, invasion and EMT of NSCLC cells. Interestingly, TIM-4 knockdown reversed the role of I …
Immune regulation by Tim-3.
Banerjee H, Kane LP. Banerjee H, et al. F1000Res. 2018 Mar 14;7:316. doi: 10.12688/f1000research.13446.1. eCollection 2018. F1000Res. 2018. PMID: 29560265 Free PMC article. Review.
Thus, Tim-3 has been associated with both inhibitory and co-stimulatory function, depending in part on the specific cell type and immune response course. ...Thus, Tim-3 has emerged as a possible therapeutic target, which is being actively explored both pre-clinicall …
Thus, Tim-3 has been associated with both inhibitory and co-stimulatory function, depending in part on the specific cell type and imm …
Tim-4 in Health and Disease: Friend or Foe?
Liu W, Xu L, Liang X, Liu X, Zhao Y, Ma C, Gao L. Liu W, et al. Front Immunol. 2020 Apr 2;11:537. doi: 10.3389/fimmu.2020.00537. eCollection 2020. Front Immunol. 2020. PMID: 32300343 Free PMC article. Review.
The expression of Tim-4 in these cells implies that Tim-4 might participate in immune related diseases. ...Here, we collectively evaluated the role of Tim-4 in health and diseases. This summary will be extremely useful to fully understand the function of T
The expression of Tim-4 in these cells implies that Tim-4 might participate in immune related diseases. ...Here, we collective …
TIM-3: An emerging target in the liver diseases.
Zhao L, Yu G, Han Q, Cui C, Zhang B. Zhao L, et al. Scand J Immunol. 2020 Apr;91(4):e12825. doi: 10.1111/sji.12825. Epub 2020 Feb 5. Scand J Immunol. 2020. PMID: 31486085 Free article. Review.
T cell immunoglobulin domain and mucin domain-containing molecule 3 (TIM-3) is found expression in the surface of terminally differentiated T cells and belongs to the TIM family of type transmembrane proteins. ...TIM-3 will provide new targets for improving c …
T cell immunoglobulin domain and mucin domain-containing molecule 3 (TIM-3) is found expression in the surface of terminally differen …
The TNO Gastro-Intestinal Model (TIM).
Minekus M. Minekus M. In: Verhoeckx K, Cotter P, López-Expósito I, Kleiveland C, Lea T, Mackie A, Requena T, Swiatecka D, Wichers H, editors. The Impact of Food Bioactives on Health: in vitro and ex vivo models [Internet]. Cham (CH): Springer; 2015. Chapter 5. In: Verhoeckx K, Cotter P, López-Expósito I, Kleiveland C, Lea T, Mackie A, Requena T, Swiatecka D, Wichers H, editors. The Impact of Food Bioactives on Health: in vitro and ex vivo models [Internet]. Cham (CH): Springer; 2015. Chapter 5. PMID: 29787065 Free Books & Documents. Review.
The TNO Gastro-Intestinal Model (TIM) is a multi-compartmental model, designed to realistically simulate conditions in the lumen of the gastro-intestinal tract. TIM is successfully used to study the gastro-intestinal behavior of a wide variety of feed, food and phar …
The TNO Gastro-Intestinal Model (TIM) is a multi-compartmental model, designed to realistically simulate conditions in the lumen of t …
Role of TIM-3 in ovarian cancer.
Xu Y, Zhang H, Huang Y, Rui X, Zheng F. Xu Y, et al. Clin Transl Oncol. 2017 Sep;19(9):1079-1083. doi: 10.1007/s12094-017-1656-8. Epub 2017 Mar 29. Clin Transl Oncol. 2017. PMID: 28357631 Review.
Overexpression of TIM-3 in innate immune cells has been found in certain types of tumor. The blockade of TIM-3 leads to sustained anti-tumor reactions. TIM-3 plays an inhibitive role for immunity in ovarian cancer. ...
Overexpression of TIM-3 in innate immune cells has been found in certain types of tumor. The blockade of TIM-3 leads to sustai …
11,565 results
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