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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1853 1
1883 2
1892 1
1893 1
1900 1
1917 1
1924 1
1925 1
1928 1
1932 1
1940 1
1944 1
1945 6
1946 55
1947 54
1948 62
1949 59
1950 57
1951 77
1952 2
1953 1
1955 1
1958 3
1960 4
1961 8
1962 10
1963 34
1964 39
1965 83
1966 93
1967 90
1968 89
1969 108
1970 111
1971 112
1972 116
1973 89
1974 17
1975 37
1976 28
1977 25
1978 27
1979 26
1980 31
1981 27
1982 33
1983 45
1984 29
1985 24
1986 29
1987 46
1988 92
1989 132
1990 201
1991 186
1992 262
1993 287
1994 311
1995 341
1996 327
1997 360
1998 351
1999 400
2000 428
2001 468
2002 488
2003 660
2004 736
2005 847
2006 1022
2007 1212
2008 1467
2009 1776
2010 2124
2011 2340
2012 2772
2013 3324
2014 3869
2015 4346
2016 4427
2017 4234
2018 4351
2019 4592
2020 5106
2021 5166
2022 5304
2023 4977
2024 1150

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64,090 results

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Page 1
mTOR substrate phosphorylation in growth control.
Battaglioni S, Benjamin D, Wälchli M, Maier T, Hall MN. Battaglioni S, et al. Cell. 2022 May 26;185(11):1814-1836. doi: 10.1016/j.cell.2022.04.013. Epub 2022 May 16. Cell. 2022. PMID: 35580586 Free article. Review.
It is activated by nutrients, growth factors, and cellular energy. TOR forms two structurally and functionally distinct complexes, TORC1 and TORC2. ...With emphasis on mammalian TOR (mTOR), we comprehensively reviewed the literature and identified all reported direc …
It is activated by nutrients, growth factors, and cellular energy. TOR forms two structurally and functionally distinct complexes, TO …
AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control.
González A, Hall MN, Lin SC, Hardie DG. González A, et al. Cell Metab. 2020 Mar 3;31(3):472-492. doi: 10.1016/j.cmet.2020.01.015. Cell Metab. 2020. PMID: 32130880 Free article. Review.
Genes encoding the AMPK and TOR complexes are found in almost all eukaryotes, suggesting that these pathways arose very early during eukaryotic evolution. ...In this review, we discuss the evolution, structure, and regulation of the AMPK and TOR pathways and the com …
Genes encoding the AMPK and TOR complexes are found in almost all eukaryotes, suggesting that these pathways arose very early during …
TOR signaling in growth and metabolism.
Wullschleger S, Loewith R, Hall MN. Wullschleger S, et al. Cell. 2006 Feb 10;124(3):471-84. doi: 10.1016/j.cell.2006.01.016. Cell. 2006. PMID: 16469695 Free article. Review.
The target of rapamycin (TOR) is a conserved Ser/Thr kinase that regulates cell growth and metabolism in response to environmental cues. Here, highlighting contributions from studies in model organisms, we review mammalian TOR complexes and the signaling branches th …
The target of rapamycin (TOR) is a conserved Ser/Thr kinase that regulates cell growth and metabolism in response to environmental cu …
Regulation of Autophagy by mTOR Signaling Pathway.
Wang Y, Zhang H. Wang Y, et al. Adv Exp Med Biol. 2019;1206:67-83. doi: 10.1007/978-981-15-0602-4_3. Adv Exp Med Biol. 2019. PMID: 31776980 Review.
Among these pathways, some pathways converge at the target of rapamycin (TOR), a highly conserved kinase important for autophagy regulation. This review will focus on the role of TOR signaling pathway in the regulation of autophagy....
Among these pathways, some pathways converge at the target of rapamycin (TOR), a highly conserved kinase important for autophagy regu …
Who does TORC2 talk to?
Xie J, Wang X, Proud CG. Xie J, et al. Biochem J. 2018 May 24;475(10):1721-1738. doi: 10.1042/BCJ20180130. Biochem J. 2018. PMID: 29794170 Review.
TOR thus plays central roles in maintaining normal cellular functions and, when dysregulated, in diverse diseases. TOR forms two distinct types of multiprotein complexes (TOR complexes 1 and 2, TORC1 and TORC2). ...
TOR thus plays central roles in maintaining normal cellular functions and, when dysregulated, in diverse diseases. TOR forms t
Contributions of TOR Signaling on Photosynthesis.
Song Y, Alyafei MS, Masmoudi K, Jaleel A, Ren M. Song Y, et al. Int J Mol Sci. 2021 Aug 20;22(16):8959. doi: 10.3390/ijms22168959. Int J Mol Sci. 2021. PMID: 34445664 Free PMC article. Review.
One of the most specific features is the involvement of TOR in plant photosynthesis. The recent development of tools for the functional analysis of plant TOR has helped to uncover the involvement of TOR signaling in several steps preceding photoautotrophy and …
One of the most specific features is the involvement of TOR in plant photosynthesis. The recent development of tools for the function …
mTOR in health and in sickness.
Liko D, Hall MN. Liko D, et al. J Mol Med (Berl). 2015 Oct;93(10):1061-73. doi: 10.1007/s00109-015-1326-7. Epub 2015 Sep 22. J Mol Med (Berl). 2015. PMID: 26391637 Review.
Target of rapamycin (TOR) is a highly conserved protein kinase that plays a key role in mediating cell growth and homeostasis. ...It is a validated drug target implicated in a variety of diseases. In this review, we describe the molecular mode of action of TOR in th …
Target of rapamycin (TOR) is a highly conserved protein kinase that plays a key role in mediating cell growth and homeostasis. ...It …
mTOR in cerebrovascular disease.
Van Skike CE, Galvan V. Van Skike CE, et al. Aging (Albany NY). 2019 Mar 13;11(5):1331-1332. doi: 10.18632/aging.101869. Aging (Albany NY). 2019. PMID: 30867339 Free PMC article. No abstract available.
The hot issue: TOR signalling network in plants.
Zhao Y, Wang XQ. Zhao Y, et al. Funct Plant Biol. 2020 Dec;48(1):1-7. doi: 10.1071/FP20071. Funct Plant Biol. 2020. PMID: 32905758 Review.
In plants, the TOR complex comprises TOR, RAPTOR (regulatory-associated protein of TOR) and LST8 (lethal with SEC13 protein 8). ...In this review, we analyse the TOR signalling network in plants and discuss the relationship between glucose and TOR
In plants, the TOR complex comprises TOR, RAPTOR (regulatory-associated protein of TOR) and LST8 (lethal with SEC13 pro …
TOR signaling in plants: conservation and innovation.
Shi L, Wu Y, Sheen J. Shi L, et al. Development. 2018 Jul 9;145(13):dev160887. doi: 10.1242/dev.160887. Development. 2018. PMID: 29986898 Free PMC article. Review.
Indeed, TOR integrates nutrient, energy, hormone, growth factor and environmental inputs to control proliferation, growth and metabolism in diverse multicellular organisms. Here, we compare the molecular composition, upstream regulators and downstream signaling relays of …
Indeed, TOR integrates nutrient, energy, hormone, growth factor and environmental inputs to control proliferation, growth and metabol …
64,090 results
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