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Pathophysiological Potentials of NRF3-Regulated Transcriptional Axes in Protein and Lipid Homeostasis.

Waku T, Kobayashi A. Waku T, et al. Int J Mol Sci. 2021 Nov 24;22(23):12686. doi: 10.3390/ijms222312686. Int J Mol Sci. 2021. PMID: 34884489 Free PMC article. Review.

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NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition.

Waku T, Hagiwara T, Tamura N, Atsumi Y, Urano Y, Suzuki M, Iwami T, Sato K, Yamamoto M, Noguchi N, Kobayashi A. Waku T, et al. iScience. 2021 Sep 28;24(10):103180. doi: 10.1016/j.isci.2021.103180. eCollection 2021 Oct 22. iScience. 2021. PMID: 34667945 Free PMC article.

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New addiction to the NRF2-related factor NRF3 in cancer cells: Ubiquitin-independent proteolysis through the 20S proteasome.

Kobayashi A, Waku T. Kobayashi A, et al. Among authors: waku t. Cancer Sci. 2020 Jan;111(1):6-14. doi: 10.1111/cas.14244. Epub 2019 Dec 14. Cancer Sci. 2020. PMID: 31742837 Free PMC article. Review.

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Klf5 suppresses ERK signaling in mouse pluripotent stem cells.

Azami T, Matsumoto K, Jeon H, Waku T, Muratani M, Niwa H, Takahashi S, Ema M. Azami T, et al. Among authors: waku t. PLoS One. 2018 Nov 19;13(11):e0207321. doi: 10.1371/journal.pone.0207321. eCollection 2018. PLoS One. 2018. PMID: 30452437 Free PMC article.

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The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection.

Omi J, Watanabe-Takahashi M, Igai K, Shimizu E, Tseng CY, Miyasaka T, Waku T, Hama S, Nakanishi R, Goto Y, Nishino Y, Miyazawa A, Natori Y, Yamashita M, Nishikawa K. Omi J, et al. Among authors: waku t. Nat Commun. 2020 Jan 9;11(1):162. doi: 10.1038/s41467-019-13974-w. Nat Commun. 2020. PMID: 31919357 Free PMC article.

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Hepatic rRNA transcription regulates high-fat-diet-induced obesity.

Oie S, Matsuzaki K, Yokoyama W, Tokunaga S, Waku T, Han SI, Iwasaki N, Mikogai A, Yasuzawa-Tanaka K, Kishimoto H, Hiyoshi H, Nakajima Y, Araki T, Kimura K, Yanagisawa J, Murayama A. Oie S, et al. Among authors: waku t. Cell Rep. 2014 May 8;7(3):807-20. doi: 10.1016/j.celrep.2014.03.038. Epub 2014 Apr 18. Cell Rep. 2014. PMID: 24746822 Free article.

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NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein.

Waku T, Nakamura N, Koji M, Watanabe H, Katoh H, Tatsumi C, Tamura N, Hatanaka A, Hirose S, Katayama H, Tani M, Kubo Y, Hamazaki J, Hamakubo T, Watanabe A, Murata S, Kobayashi A. Waku T, et al. Mol Cell Biol. 2020 Apr 28;40(10):e00597-19. doi: 10.1128/MCB.00597-19. Print 2020 Apr 28. Mol Cell Biol. 2020. PMID: 32123008 Free PMC article.

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NFE2L1 and NFE2L3 Complementarily Maintain Basal Proteasome Activity in Cancer Cells through CPEB3-Mediated Translational Repression.

Waku T, Katayama H, Hiraoka M, Hatanaka A, Nakamura N, Tanaka Y, Tamura N, Watanabe A, Kobayashi A. Waku T, et al. Mol Cell Biol. 2020 Jun 29;40(14):e00010-20. doi: 10.1128/MCB.00010-20. Print 2020 Jun 29. Mol Cell Biol. 2020. PMID: 32366381 Free PMC article.

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β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells.

Aono S, Hatanaka A, Hatanaka A, Gao Y, Hippo Y, Taketo MM, Waku T, Kobayashi A. Aono S, et al. Among authors: waku t. Int J Mol Sci. 2019 Jul 8;20(13):3344. doi: 10.3390/ijms20133344. Int J Mol Sci. 2019. PMID: 31288376 Free PMC article.

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Regulation of the vitamin D receptor by vitamin D lactam derivatives.

Asano L, Waku T, Abe R, Kuwabara N, Ito I, Yanagisawa J, Nagasawa K, Shimizu T. Asano L, et al. Among authors: waku t. FEBS Lett. 2016 Sep;590(18):3270-9. doi: 10.1002/1873-3468.12348. Epub 2016 Aug 23. FEBS Lett. 2016. PMID: 27500498 Free article.

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