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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1977 1
1985 2
1986 2
1987 10
1988 11
1989 10
1990 12
1991 22
1992 17
1993 17
1994 16
1995 27
1996 22
1997 29
1998 31
1999 27
2000 24
2001 24
2002 25
2003 24
2004 23
2005 22
2006 25
2007 23
2008 28
2009 18
2010 21
2011 21
2012 26
2013 21
2014 30
2015 20
2016 16
2017 26
2018 26
2019 24
2020 23
2021 24
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713 results
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Filters applied: . Clear all The following term was not found in PubMed: Paragahawewa
Page 1
64Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-Asp-cyclohexylalanine-Phe-d-Ser-d-Arg-Tyr-Leu-Trp-Ser-NH2 (AE105-NH2).
Leung K. Leung K. 2012 May 18 [updated 2012 Aug 23]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 May 18 [updated 2012 Aug 23]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 22934319 Free Books & Documents. Review.
Several families of proteases are involved in atherogenesis, myocardial infarction, angiogenesis, and tumor invasion and metastasis (4-7). Urokinase-type plasminogen activator (uPA) is a serine protease (8, 9). The uPA/uPA receptor (uPAR) system is responsibl …
Several families of proteases are involved in atherogenesis, myocardial infarction, angiogenesis, and tumor invasion and metastasis (4-7). U …
Ulipristal acetate: a new emergency contraceptive.
Sullivan JL, Bulloch MN. Sullivan JL, et al. Expert Rev Clin Pharmacol. 2011 Jul;4(4):417-27. doi: 10.1586/ecp.11.21. Expert Rev Clin Pharmacol. 2011. PMID: 22114852 Review.
This selective progesterone receptor modulator appears to be more effective than the levonorgestrel-containing emergency contraceptive, which must be taken within 72 h of unprotected intercourse. According to pharmacodynamic trials, UPA delays follicular maturation …
This selective progesterone receptor modulator appears to be more effective than the levonorgestrel-containing emergency contraceptive, whic …
68Ga-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-Asp-cyclohexylalanine-Phe-d-Ser-d-Arg-Tyr-Leu-Trp-Ser-NH2 (AE105-NH2).
Leung K. Leung K. 2012 May 20 [updated 2012 Aug 23]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 May 20 [updated 2012 Aug 23]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 22934318 Free Books & Documents. Review.
Several families of proteases are involved in atherogenesis, myocardial infarction, angiogenesis, and tumor invasion and metastasis (4-7). Urokinase-type plasminogen activator (uPA) is a serine protease (8, 9). The uPA/uPA receptor (uPAR) system is responsibl …
Several families of proteases are involved in atherogenesis, myocardial infarction, angiogenesis, and tumor invasion and metastasis (4-7). U …
Exposure to benzylpenicillin after different dosage regimens in growing pigs.
Sjölund M, Ekstrand C, Wallgren P, Bondesson U, Pringle M, Bengtsson B. Sjölund M, et al. Acta Vet Scand. 2020 Sep 17;62(1):55. doi: 10.1186/s13028-020-00552-0. Acta Vet Scand. 2020. PMID: 32943077 Free PMC article.
RESULTS: After intravenous administration of benzylpenicillin (n = 6), maximum plasma concentration (C(max)), 1860-9318 g/L, was observed after 15 min. At four h, plasma concentrations decreased to 15-76 g/L. After intramuscular administration of ETH (n = 6) C(max), 1000-4 …
RESULTS: After intravenous administration of benzylpenicillin (n = 6), maximum plasma concentration (C(max)), 1860-9318 g/L, was observed af …
Emergency contraception: clinical outcomes.
Glasier A. Glasier A. Contraception. 2013 Mar;87(3):309-13. doi: 10.1016/j.contraception.2012.08.027. Epub 2012 Oct 4. Contraception. 2013. PMID: 23040128 Review.
This review considers the safety and efficacy of three commonly used methods -- levonorgestrel (LNG-EC), ulipristal acetate (UPA) and the copper intrauterine device. All are extremely safe, and side effects are minimal. ...Although the true effectiveness of EC is impossibl …
This review considers the safety and efficacy of three commonly used methods -- levonorgestrel (LNG-EC), ulipristal acetate (UPA) and …
Identification and preclinical development of an anti-proteolytic uPA antibody for rheumatoid arthritis.
Almholt K, Wang J, Pass J, Røder G, Padkjær SB, Hebsgaard JB, Xia W, Yang L, Forsell J, Breinholt VM, Thygesen P, Agersø H, Loftager M, Usher PA. Almholt K, et al. J Mol Med (Berl). 2020 Apr;98(4):585-593. doi: 10.1007/s00109-020-01889-9. Epub 2020 Feb 27. J Mol Med (Berl). 2020. PMID: 32108909
At a dose level of 20.6 mg kg(-1), the antibody had a plasma half-life of 210 h. Plasma uPA activity, a pharmacodynamic marker of anti-uPA therapy, was reduced to below the detection limit during treatment, indicating that an efficacious plasma concentration …
At a dose level of 20.6 mg kg(-1), the antibody had a plasma half-life of 210 h. Plasma uPA activity, a pharmacodynamic marker …
Rapid detection of urokinase plasminogen activator using flexible paper-based graphene-gold platform.
Sharma B, Parajuli P, Podila R. Sharma B, et al. Biointerphases. 2020 Feb 4;15(1):011004. doi: 10.1116/1.5128889. Biointerphases. 2020. PMID: 32019314 Free PMC article.
Many studies have shown that urokinase plasminogen activator (uPA) is causally involved in promoting cancer invasion and metastasis. ...Here, the authors developed a novel and scalable uPA sensor based on a graphene-gold nanoparticle platform that uses fluorescence …
Many studies have shown that urokinase plasminogen activator (uPA) is causally involved in promoting cancer invasion and metastasis. …
uPA impairs cerebrovasodilation after hypoxia/ischemia through LRP and ERK MAPK.
Armstead WM, Cines DB, Bdeir K, Kulikovskaya I, Stein SC, Higazi AA. Armstead WM, et al. Brain Res. 2008 Sep 22;1231:121-31. doi: 10.1016/j.brainres.2008.06.115. Epub 2008 Jul 8. Brain Res. 2008. PMID: 18656457 Free PMC article.
CSF uPA increased from 9+/-2 to 52+/-8 and 140+/-21 ng/ml at 1 and 4 h after H/I, respectively. The LRP antagonist receptor associated protein (RAP) and anti-LRP antibody blunted the increase in CSF uPA at 1 h (17+/-2 ng/ml) but not 4 h p …
CSF uPA increased from 9+/-2 to 52+/-8 and 140+/-21 ng/ml at 1 and 4 h after H/I, respectively. The LRP antagonist rece …
Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture.
Vaisar T, Hu JH, Airhart N, Fox K, Heinecke J, Nicosia RF, Kohler T, Potter ZE, Simon GM, Dix MM, Cravatt BF, Gharib SA, Dichek DA. Vaisar T, et al. Circ Res. 2020 Sep 25;127(8):997-1022. doi: 10.1161/CIRCRESAHA.120.317295. Epub 2020 Jul 30. Circ Res. 2020. PMID: 32762496 Free PMC article.
METHODS AND RESULTS: We performed shotgun proteomics analyses of aortas of transgenic mice with macrophage-specific overexpression of urokinase (SR-uPA(+/0) mice) and of SR-uPA(+/0) bone marrow transplant recipients, and we used bioinformatic tools to evaluate prote …
METHODS AND RESULTS: We performed shotgun proteomics analyses of aortas of transgenic mice with macrophage-specific overexpression of urokin …
Selective progesterone receptor modulators: an update.
Benagiano G, Bastianelli C, Farris M, Brosens I. Benagiano G, et al. Expert Opin Pharmacother. 2014 Jul;15(10):1403-15. doi: 10.1517/14656566.2014.914494. Epub 2014 Apr 30. Expert Opin Pharmacother. 2014. PMID: 24787486 Review.
Two SPRMs are clinically utilized today: mifepristone (MFP) and ulipristal acetate (UPA). MFP is available for EC in up to 120 h following unprotected intercourse. A dose of 10 mg is significantly more effective than levonorgestrel (LNG). In a metanalysis of the use …
Two SPRMs are clinically utilized today: mifepristone (MFP) and ulipristal acetate (UPA). MFP is available for EC in up to 120 h
713 results