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Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces.
Uttagomol J, Ahmad US, Rehman A, Huang Y, Laly AC, Kang A, Soetaert J, Chance R, Teh MT, Connelly JT, Wan H. Uttagomol J, et al. Among authors: Ahmad US. Int J Mol Sci. 2019 Dec 10;20(24):6221. doi: 10.3390/ijms20246221. Int J Mol Sci. 2019. PMID: 31835537 Free PMC article.
The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53.
Rehman A, Cai Y, Hünefeld C, Jedličková H, Huang Y, Teck Teh M, Sharif Ahmad U, Uttagomol J, Wang Y, Kang A, Warnes G, Harwood C, Bergamaschi D, Kenneth Parkinson E, Röcken M, Wan H. Rehman A, et al. Among authors: Sharif Ahmad U. Cell Death Dis. 2019 Oct 3;10(10):750. doi: 10.1038/s41419-019-1988-0. Cell Death Dis. 2019. PMID: 31582719 Free PMC article.
Desmoglein-3 acts as a pro-survival protein by suppressing reactive oxygen species and doming whilst augmenting the tight junctions in MDCK cells.
Li X, Ahmad US, Huang Y, Uttagomol J, Rehman A, Zhou K, Warnes G, McArthur S, Parkinson EK, Wan H. Li X, et al. Among authors: Ahmad US. Mech Ageing Dev. 2019 Dec;184:111174. doi: 10.1016/j.mad.2019.111174. Epub 2019 Oct 31. Mech Ageing Dev. 2019. PMID: 31678215 Free article.
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