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Neurotrophic Effect of Asiatic acid, a Triterpene of Centella asiatica Against Chronic 1-Methyl 4-Phenyl 1, 2, 3, 6-Tetrahydropyridine Hydrochloride/Probenecid Mouse Model of Parkinson's disease: The Role of MAPK, PI3K-Akt-GSK3β and mTOR Signalling Pathways.
Nataraj J, Manivasagam T, Justin Thenmozhi A, Essa MM. Nataraj J, et al. Neurochem Res. 2017 May;42(5):1354-1365. doi: 10.1007/s11064-017-2183-2. Epub 2017 Feb 8. Neurochem Res. 2017. PMID: 28181071
Regulation of various signalling (Ras-MAPK, PI3K and AKT) pathways by augmented activity of neurotrophic factors (NTFs) could prevent or halt the progress of dopaminergic loss in Parkinson's disease (PD). Various in vitro and in vivo experimental studies indicated anti-par …
Regulation of various signalling (Ras-MAPK, PI3K and AKT) pathways by augmented activity of neurotrophic factors (NTFs) could prevent or hal …
Attenuation of Aluminum Chloride-Induced Neuroinflammation and Caspase Activation Through the AKT/GSK-3β Pathway by Hesperidin in Wistar Rats.
Justin-Thenmozhi A, Dhivya Bharathi M, Kiruthika R, Manivasagam T, Borah A, Essa MM. Justin-Thenmozhi A, et al. Neurotox Res. 2018 Oct;34(3):463-476. doi: 10.1007/s12640-018-9904-4. Epub 2018 Apr 23. Neurotox Res. 2018. PMID: 29687202
Our results imply that treatment with hesperidin might be a potent option for treating the symptoms of cognitive impairment in Alzheimer's disease by targeting its most prominent hallmarks....
Our results imply that treatment with hesperidin might be a potent option for treating the symptoms of cognitive impairment in Alzheimer' …