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Year Number of Results
2011 2
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61 results

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Page 1
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept.
Coskun T, Urva S, Roell WC, Qu H, Loghin C, Moyers JS, O'Farrell LS, Briere DA, Sloop KW, Thomas MK, Pirro V, Wainscott DB, Willard FS, Abernathy M, Morford L, Du Y, Benson C, Gimeno RE, Haupt A, Milicevic Z. Coskun T, et al. Among authors: pirro v. Cell Metab. 2022 Sep 6;34(9):1234-1247.e9. doi: 10.1016/j.cmet.2022.07.013. Epub 2022 Aug 18. Cell Metab. 2022. PMID: 35985340 Free article.
GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice.
Samms RJ, Christe ME, Collins KA, Pirro V, Droz BA, Holland AK, Friedrich JL, Wojnicki S, Konkol DL, Cosgrove R, Furber EPC, Ruan X, O'Farrell LS, Long AM, Dogra M, Willency JA, Lin Y, Ding L, Cheng CC, Cabrera O, Briere DA, Alsina-Fernandez J, Gimeno RE, Moyers JS, Coskun T, Coghlan MP, Sloop KW, Roell WC. Samms RJ, et al. Among authors: pirro v. J Clin Invest. 2021 Jun 15;131(12):e146353. doi: 10.1172/JCI146353. J Clin Invest. 2021. PMID: 34003802 Free PMC article.
Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue.
Samms RJ, Zhang G, He W, Ilkayeva O, Droz BA, Bauer SM, Stutsman C, Pirro V, Collins KA, Furber EC, Coskun T, Sloop KW, Brozinick JT, Newgard CB. Samms RJ, et al. Among authors: pirro v. Mol Metab. 2022 Oct;64:101550. doi: 10.1016/j.molmet.2022.101550. Epub 2022 Jul 31. Mol Metab. 2022. PMID: 35921984 Free PMC article.
The GIP receptor activates futile calcium cycling in white adipose tissue to increase energy expenditure and drive weight loss in mice.
Yu X, Chen S, Funcke JB, Straub LG, Pirro V, Emont MP, Droz BA, Collins KA, Joung C, Pearson MJ, James CM, Babu GJ, Efthymiou V, Vernon A, Patti ME, An YA, Rosen ED, Coghlan MP, Samms RJ, Scherer PE, Kusminski CM. Yu X, et al. Among authors: pirro v. Cell Metab. 2025 Jan 7;37(1):187-204.e7. doi: 10.1016/j.cmet.2024.11.003. Epub 2024 Dec 5. Cell Metab. 2025. PMID: 39642881 Free PMC article.
Treatment with orforglipron, an oral glucagon like peptide-1 receptor agonist, is associated with improvements of CV risk biomarkers in participants with type 2 diabetes or obesity without diabetes.
Wharton S, Rosenstock J, Konige M, Lin Y, Duffin K, Wilson J, Banerjee H, Pirro V, Kazda C, Mather K. Wharton S, et al. Among authors: pirro v. Cardiovasc Diabetol. 2025 Jun 6;24(1):240. doi: 10.1186/s12933-025-02781-x. Cardiovasc Diabetol. 2025. PMID: 40481478 Free PMC article. Clinical Trial.
Glucose-dependent insulinotropic polypeptide receptor signaling in oligodendrocytes increases the weight-loss action of GLP-1R agonism.
Hansford R, Buller S, Tsang AH, Benoit S, Roberts AG, Erskine E, Brown T, Pirro V, Reimann F, Harada N, Inagaki N, Samms RJ, Broichhagen J, Hodson DJ, Adriaenssens A, Park S, Blouet C. Hansford R, et al. Among authors: pirro v. Cell Metab. 2025 Sep 2;37(9):1820-1834.e5. doi: 10.1016/j.cmet.2025.07.009. Epub 2025 Aug 13. Cell Metab. 2025. PMID: 40812310 Free article.
OSAS Severity and Occlusal Parameters: A Prospective Study among Adult Subjects with Comorbidities.
Luzzi V, Altieri F, Di Carlo G, Guaragna M, Pirro V, Marasca B, Cotticelli L, Mazur M, Di Giacomo P, Di Paolo C, Brunori M, Piperno G, Magliulo G, Martini A, Pietrafesa E, Polimeni A. Luzzi V, et al. Among authors: pirro v. Int J Environ Res Public Health. 2022 May 1;19(9):5517. doi: 10.3390/ijerph19095517. Int J Environ Res Public Health. 2022. PMID: 35564910 Free PMC article.
61 results