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Development of Large-Scale Downstream Processing for Lentiviral Vectors.
Valkama AJ, Oruetxebarria I, Lipponen EM, Leinonen HM, Käyhty P, Hynynen H, Turkki V, Malinen J, Miinalainen T, Heikura T, Parker NR, Ylä-Herttuala S, Lesch HP. Valkama AJ, et al. Among authors: turkki v. Mol Ther Methods Clin Dev. 2020 Mar 30;17:717-730. doi: 10.1016/j.omtm.2020.03.025. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32346549 Free PMC article.
Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
Gupta K, Turkki V, Sherrill-Mix S, Hwang Y, Eilers G, Taylor L, McDanal C, Wang P, Temelkoff D, Nolte RT, Velthuisen E, Jeffrey J, Van Duyne GD, Bushman FD. Gupta K, et al. Among authors: turkki v. PLoS Biol. 2016 Dec 9;14(12):e1002584. doi: 10.1371/journal.pbio.1002584. eCollection 2016 Dec. PLoS Biol. 2016. PMID: 27935939 Free PMC article.
rDNA-directed integration by an HIV-1 integrase--I-PpoI fusion protein.
Schenkwein D, Turkki V, Ahlroth MK, Timonen O, Airenne KJ, Ylä-Herttuala S. Schenkwein D, et al. Among authors: turkki v. Nucleic Acids Res. 2013 Mar 1;41(5):e61. doi: 10.1093/nar/gks1438. Epub 2012 Dec 28. Nucleic Acids Res. 2013. PMID: 23275537 Free PMC article.
Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells.
Leinonen HM, Lipponen EM, Valkama AJ, Hynynen H, Oruetxebarria I, Turkki V, Olsson V, Kurkipuro J, Samaranayake H, Määttä AM, Parker NR, Ylä-Herttuala S, Lesch HP. Leinonen HM, et al. Among authors: turkki v. Mol Ther Methods Clin Dev. 2019 Aug 29;15:63-71. doi: 10.1016/j.omtm.2019.08.006. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31649956 Free PMC article.