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Year Number of Results
2003 1
2005 1
2006 1
2008 2
2009 1
2010 5
2011 8
2012 3
2013 6
2014 8
2019 1
2020 1
2022 1
2023 0

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35 results

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Page 1
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
Kancharla P, Dodean RA, Li Y, Pou S, Pybus B, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, Sousa J, Marcsisin S, Caridha D, Xie L, Vuong C, Zeng Q, Zhang J, Zhang P, Lin H, Butler K, Roncal N, Gaynor-Ohnstad L, Leed SE, Nolan C, Ceja FG, Rasmussen SA, Tumwebaze PK, Rosenthal PJ, Mu J, Bayles BR, Cooper RA, Reynolds KA, Smilkstein MJ, Riscoe MK, Kelly JX. Kancharla P, et al. Among authors: melendez v. J Med Chem. 2020 Jun 11;63(11):6179-6202. doi: 10.1021/acs.jmedchem.0c00539. Epub 2020 May 26. J Med Chem. 2020. PMID: 32390431 Free PMC article.
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Dodean RA, Kancharla P, Li Y, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, Sousa J, Marcsisin S, Caridha D, Xie L, Vuong C, Zeng Q, Zhang J, Zhang P, Lin H, Butler K, Roncal N, Gaynor-Ohnstad L, Leed SE, Nolan C, Huezo SJ, Rasmussen SA, Stephens MT, Tan JC, Cooper RA, Smilkstein MJ, Pou S, Winter RW, Riscoe MK, Kelly JX. Dodean RA, et al. Among authors: melendez v. J Med Chem. 2019 Apr 11;62(7):3475-3502. doi: 10.1021/acs.jmedchem.8b01961. Epub 2019 Mar 21. J Med Chem. 2019. PMID: 30852885 Free PMC article.
New imidazolidinedione derivatives as antimalarial agents.
Zhang L, Sathunuru R, Luong T, Melendez V, Kozar MP, Lin AJ. Zhang L, et al. Among authors: melendez v. Bioorg Med Chem. 2011 Feb 15;19(4):1541-9. doi: 10.1016/j.bmc.2010.12.028. Epub 2010 Dec 16. Bioorg Med Chem. 2011. PMID: 21282058
Effectiveness of BNT162b2 and mRNA-1273 Second Doses and Boosters for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and SARS-CoV-2-Related Hospitalizations: A Statewide Report From the Minnesota Electronic Health Record Consortium.
Drawz PE, DeSilva M, Bodurtha P, Vazquez Benitez G, Murray A, Chamberlain AM, Dudley RA, Waring S, Kharbanda AB, Murphy D, Muscoplat MH, Melendez V, Margolis KL, McFarling L, Lupu R, Winkelman TNA, Johnson SG. Drawz PE, et al. Among authors: melendez v. Clin Infect Dis. 2022 Sep 14;75(5):890-892. doi: 10.1093/cid/ciac110. Clin Infect Dis. 2022. PMID: 35137021 Free PMC article.
Primaquine failure and cytochrome P-450 2D6 in Plasmodium vivax malaria.
Bennett JW, Pybus BS, Yadava A, Tosh D, Sousa JC, McCarthy WF, Deye G, Melendez V, Ockenhouse CF. Bennett JW, et al. Among authors: melendez v. N Engl J Med. 2013 Oct 3;369(14):1381-2. doi: 10.1056/NEJMc1301936. N Engl J Med. 2013. PMID: 24088113 Free article. Clinical Trial. No abstract available.
The metabolism of primaquine to its active metabolite is dependent on CYP 2D6.
Pybus BS, Marcsisin SR, Jin X, Deye G, Sousa JC, Li Q, Caridha D, Zeng Q, Reichard GA, Ockenhouse C, Bennett J, Walker LA, Ohrt C, Melendez V. Pybus BS, et al. Among authors: melendez v. Malar J. 2013 Jun 20;12:212. doi: 10.1186/1475-2875-12-212. Malar J. 2013. PMID: 23782898 Free PMC article.
35 results