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Year Number of Results
2002 1
2003 2
2005 2
2006 5
2007 2
2008 1
2009 7
2010 6
2011 4
2012 6
2013 6
2014 3
2015 11
2016 8
2017 10
2018 9
2019 6
2020 6
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86 results
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Page 1
How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?
Jorda R, Hendrychová D, Voller J, Řezníčková E, Gucký T, Kryštof V. Jorda R, et al. Among authors: krystof v. J Med Chem. 2018 Oct 25;61(20):9105-9120. doi: 10.1021/acs.jmedchem.8b00049. Epub 2018 Oct 5. J Med Chem. 2018. PMID: 30234987
Synthesis and anti-mitotic activity of 2,4- or 2,6-disubstituted- and 2,4,6-trisubstituted-2H-pyrazolo[4,3-c]pyridines.
Milišiūnaitė V, Arbačiauskienė E, Řezníčková E, Jorda R, Malínková V, Žukauskaitė A, Holzer W, Šačkus A, Kryštof V. Milišiūnaitė V, et al. Among authors: krystof v. Eur J Med Chem. 2018 Apr 25;150:908-919. doi: 10.1016/j.ejmech.2018.03.037. Epub 2018 Mar 16. Eur J Med Chem. 2018. PMID: 29602037
6-Substituted purines as ROCK inhibitors with anti-metastatic activity.
Voller J, Zahajská L, Plíhalová L, Jeřábková J, Burget D, Pataki AC, Kryštof V, Zatloukal M, Brábek J, Rösel D, Mik V, Tkáč M, Pospíšil T, Gucký T, Doležal K, Strnad M. Voller J, et al. Among authors: krystof v. Bioorg Chem. 2019 Sep;90:103005. doi: 10.1016/j.bioorg.2019.103005. Epub 2019 Jun 6. Bioorg Chem. 2019. PMID: 31271944
Synthesis, Bacteriostatic and Anticancer Activity of Novel Phenanthridines Structurally Similar to Benzo[c]phenanthridine Alkaloids.
Lasák P, Motyka K, Kryštof V, Stýskala J. Lasák P, et al. Among authors: krystof v. Molecules. 2018 Aug 27;23(9):2155. doi: 10.3390/molecules23092155. Molecules. 2018. PMID: 30150591 Free PMC article.
Potential Clinical Uses of CDK Inhibitors: Lessons from Synthetic Lethality Screens.
Vymětalová L, Kryštof V. Vymětalová L, et al. Among authors: krystof v. Med Res Rev. 2015 Nov;35(6):1156-74. doi: 10.1002/med.21354. Epub 2015 Jun 25. Med Res Rev. 2015. PMID: 26114963 Review.
Cyclin-dependent kinase inhibitors inspired by roscovitine: purine bioisosteres.
Jorda R, Paruch K, Krystof V. Jorda R, et al. Among authors: krystof v. Curr Pharm Des. 2012;18(20):2974-80. doi: 10.2174/138161212800672804. Curr Pharm Des. 2012. PMID: 22571665 Review.
Cyclin-dependent kinase inhibitors as anticancer drugs.
Krystof V, Uldrijan S. Krystof V, et al. Curr Drug Targets. 2010 Mar;11(3):291-302. doi: 10.2174/138945010790711950. Curr Drug Targets. 2010. PMID: 20210754 Review.
Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014).
Malínková V, Vylíčil J, Kryštof V. Malínková V, et al. Among authors: krystof v. Expert Opin Ther Pat. 2015;25(9):953-70. doi: 10.1517/13543776.2015.1045414. Epub 2015 Jul 13. Expert Opin Ther Pat. 2015. PMID: 26161698 Review.
Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl- N6-(4-morpholin-4-ylmethyl-phenyl)- 9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations.
Gucký T, Řezníčková E, Radošová Muchová T, Jorda R, Klejová Z, Malínková V, Berka K, Bazgier V, Ajani H, Lepšík M, Divoký V, Kryštof V. Gucký T, et al. Among authors: krystof v. J Med Chem. 2018 May 10;61(9):3855-3869. doi: 10.1021/acs.jmedchem.7b01529. Epub 2018 Apr 30. J Med Chem. 2018. PMID: 29672049
Imidazo[1,2-c]pyrimidin-5(6H)-one as a novel core of cyclin-dependent kinase 2 inhibitors: Synthesis, activity measurement, docking, and quantum mechanical scoring.
Ajani H, Jansa J, Köprülüoğlu C, Hobza P, Kryštof V, Lyčka A, Lepsik M. Ajani H, et al. Among authors: krystof v. J Mol Recognit. 2018 Sep;31(9):e2720. doi: 10.1002/jmr.2720. Epub 2018 Apr 23. J Mol Recognit. 2018. PMID: 29687635
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