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Showing results for vladimir mirnas
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Transcription Factors Regulating Embryonic Development of Pulmonary Vasculature.
Bolte C, Whitsett JA, Kalin TV, Kalinichenko VV. Bolte C, et al. Adv Anat Embryol Cell Biol. 2018;228:1-20. doi: 10.1007/978-3-319-68483-3_1. Adv Anat Embryol Cell Biol. 2018. PMID: 29288383 Review.
Studies in transgenic and knockout mouse models demonstrate that normal lung morphogenesis requires coordinated interactions between cells lining the tubules, which end in peripheral saccules, juxtaposed to an extensive network of capillaries. Multiple growth factors, microRNA
Studies in transgenic and knockout mouse models demonstrate that normal lung morphogenesis requires coordinated interactions between cells l …
Labeling microRNA precursors for Dicer assays.
Schlösser V, Hall J. Schlösser V, et al. Anal Biochem. 2019 Aug 15;579:35-37. doi: 10.1016/j.ab.2019.05.008. Epub 2019 May 12. Anal Biochem. 2019. PMID: 31091428
Excision of the terminal loop of precursor microRNAs (pre-miRNA) by Dicer generates miRNA duplexes, comprising 5p and 3p strands. Dicer often cleaves the RNA at more than one site, producing mature miRNAs with heterogeneous 3' and 5' ends. As pre-mi
Excision of the terminal loop of precursor microRNAs (pre-miRNA) by Dicer generates miRNA duplexes, comprising 5p and 3 …
One- and Two-Dimensional High-Resolution NMR from Flat Surfaces.
Walder BJ, Berk C, Liao WC, Rossini AJ, Schwarzwälder M, Pradere U, Hall J, Lesage A, Copéret C, Emsley L. Walder BJ, et al. ACS Cent Sci. 2019 Mar 27;5(3):515-523. doi: 10.1021/acscentsci.8b00916. Epub 2019 Feb 11. ACS Cent Sci. 2019. PMID: 30937379 Free PMC article.
We demonstrate that, with this ultrahigh NMR sensitivity, (31)P NMR can be used to observe DNA bound to miRNA, to sense conformational changes due to ion binding, and to follow photochemical degradation reactions....
We demonstrate that, with this ultrahigh NMR sensitivity, (31)P NMR can be used to observe DNA bound to miRNA, to sense conformationa …
MicroRNA Biogenesis Pathway Genes Are Deregulated in Colorectal Cancer.
Vychytilova-Faltejskova P, Svobodova Kovarikova A, Grolich T, Prochazka V, Slaba K, Machackova T, Halamkova J, Svoboda M, Kala Z, Kiss I, Slaby O. Vychytilova-Faltejskova P, et al. Int J Mol Sci. 2019 Sep 10;20(18):4460. doi: 10.3390/ijms20184460. Int J Mol Sci. 2019. PMID: 31510013 Free PMC article.
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression. ...Thus, we have measured the expression of 19 genes involved in miRNAs biogenesis pathway in tumor tissues of 239 colorectal cancer (CRC) patients, 17 CRC pati
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression. ...Thus, we have measured t
Translational Potential of MicroRNAs for Preoperative Staging and Prediction of Chemoradiotherapy Response in Rectal Cancer.
Machackova T, Prochazka V, Kala Z, Slaby O. Machackova T, et al. Cancers (Basel). 2019 Oct 12;11(10):1545. doi: 10.3390/cancers11101545. Cancers (Basel). 2019. PMID: 31614848 Free PMC article. Review.
Circulating miRNAs are promising non-invasive biomarkers that could allow monitoring of a patient throughout the whole therapeutic process. This mini-review aims to summarize the current knowledge on miRNAs and circulating miRNAs involved in the prediction of …
Circulating miRNAs are promising non-invasive biomarkers that could allow monitoring of a patient throughout the whole therapeutic pr …
MiR-CLIP reveals iso-miR selective regulation in the miR-124 targetome.
Wang Y, Soneson C, Malinowska AL, Laski A, Ghosh S, Kanitz A, Gebert LFR, Robinson MD, Hall J. Wang Y, et al. Nucleic Acids Res. 2021 Jan 11;49(1):25-37. doi: 10.1093/nar/gkaa1117. Nucleic Acids Res. 2021. PMID: 33300035 Free PMC article.
To ascertain the scope of non-canonical miRNA targeting, methods are needed that identify all targets of a given miRNA. ...In summary, access to the miR-124 targetome via miR-CLIP revealed for the first time how heterogeneous processing of miRNAs combined wit …
To ascertain the scope of non-canonical miRNA targeting, methods are needed that identify all targets of a given miRNA. ...In …
Pre-operative Plasma miR-21-5p Is a Sensitive Biomarker and Independent Prognostic Factor in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Surgical Resection.
Karasek P, Gablo N, Hlavsa J, Kiss I, Vychytilova-Faltejskova P, Hermanova M, Kala Z, Slaby O, Prochazka V. Karasek P, et al. Cancer Genomics Proteomics. 2018 Jul-Aug;15(4):321-327. doi: 10.21873/cgp.20090. Cancer Genomics Proteomics. 2018. PMID: 29976637 Free PMC article.
Blood plasma microRNAs (miRNAs) are emerging as a clinically useful tool for non-invasive detection and prognosis estimation in various cancer types including pancreatic ductal adenocarcinoma (PDAC). ...Plasma levels of miRNAs were determined using quantitati …
Blood plasma microRNAs (miRNAs) are emerging as a clinically useful tool for non-invasive detection and prognosis estimation i …
Plasma microRNA biomarkers for detection of mild cognitive impairment.
Sheinerman KS, Tsivinsky VG, Crawford F, Mullan MJ, Abdullah L, Umansky SR. Sheinerman KS, et al. Aging (Albany NY). 2012 Sep;4(9):590-605. doi: 10.18632/aging.100486. Aging (Albany NY). 2012. PMID: 23001356 Free PMC article.
Early stages of many neurodegenerative diseases, such as Alzheimer's disease, vascular and frontotemporal dementia, and Parkinson's disease, are frequently associated with Mild Cognitive Impairment (MCI). ...Here, we examined the feasibility of using pairs of brain- …
Early stages of many neurodegenerative diseases, such as Alzheimer's disease, vascular and frontotemporal dementia, and Parkinson' …
Design and Application of Mini-libraries of miRNA Probes for an Efficient and Versatile miRNA-mRNA Cross-linking.
Malinowska AL, Laski A, Hall J. Malinowska AL, et al. Chemistry. 2021 Jul 12;27(39):10193-10200. doi: 10.1002/chem.202101171. Epub 2021 Jun 4. Chemistry. 2021. PMID: 34000095 Free PMC article.
MicroRNAs constitute a class of endogenous, non-coding RNAs that influence various processes within the cell. ...Here, we present a new concept of probe design to achieve an efficient and sequence-independent miRNA-mRNA cross-linking. The new strategy is based on th
MicroRNAs constitute a class of endogenous, non-coding RNAs that influence various processes within the cell. ...Here, we present a n
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