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Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22.
van der Merwe PA, Crocker PR, Vinson M, Barclay AN, Schauer R, Kelm S. van der Merwe PA, et al. J Biol Chem. 1996 Apr 19;271(16):9273-80. J Biol Chem. 1996. PMID: 8621588 Free article.
All 12 mutations that abrogated binding to CD45-thy without disrupting antibody binding were of residues within the GFCC'C" beta-sheet of domain 1. These residues are predicted to form a contiguous binding site centered around an arginine residue in the F strand that is co …
All 12 mutations that abrogated binding to CD45-thy without disrupting antibody binding were of residues within the GFCC'C" beta-shee …