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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 4
2004 3
2005 3
2006 2
2007 7
2008 9
2009 10
2010 15
2011 16
2012 9
2013 12
2014 18
2015 17
2016 20
2017 18
2018 27
2019 12
2020 6
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185 results
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Page 1
Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases.
Schmidt M, Rohe A, Platzer C, Najjar A, Erdmann F, Sippl W. Schmidt M, et al. Among authors: Sippl W. Molecules. 2017 Nov 23;22(12):2045. doi: 10.3390/molecules22122045. Molecules. 2017. PMID: 29168755 Free PMC article. Review.
MMP-14 degrades tropoelastin and elastin.
Miekus N, Luise C, Sippl W, Baczek T, Schmelzer CEH, Heinz A. Miekus N, et al. Among authors: Sippl W. Biochimie. 2019 Oct;165:32-39. doi: 10.1016/j.biochi.2019.07.001. Epub 2019 Jul 3. Biochimie. 2019. PMID: 31278967
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells.
Plesch E, Chen CC, Butz E, Scotto Rosato A, Krogsaeter EK, Yinan H, Bartel K, Keller M, Robaa D, Teupser D, Holdt LM, Vollmar AM, Sippl W, Puertollano R, Medina D, Biel M, Wahl-Schott C, Bracher F, Grimm C. Plesch E, et al. Among authors: Sippl W. Elife. 2018 Nov 27;7:e39720. doi: 10.7554/eLife.39720. Elife. 2018. PMID: 30479274 Free PMC article.
Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).
Schiedel M, Herp D, Hammelmann S, Swyter S, Lehotzky A, Robaa D, Oláh J, Ovádi J, Sippl W, Jung M. Schiedel M, et al. Among authors: Sippl W. J Med Chem. 2018 Jan 25;61(2):482-491. doi: 10.1021/acs.jmedchem.6b01872. Epub 2017 Apr 17. J Med Chem. 2018. PMID: 28379698
The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases.
Roatsch M, Hoffmann I, Abboud MI, Hancock RL, Tarhonskaya H, Hsu KF, Wilkins SE, Yeh TL, Lippl K, Serrer K, Moneke I, Ahrens TD, Robaa D, Wenzler S, Barthes NPF, Franz H, Sippl W, Lassmann S, Diederichs S, Schleicher E, Schofield CJ, Kawamura A, Schüle R, Jung M. Roatsch M, et al. Among authors: Sippl W. ACS Chem Biol. 2019 Aug 16;14(8):1737-1750. doi: 10.1021/acschembio.9b00289. Epub 2019 Jul 19. ACS Chem Biol. 2019. PMID: 31287655
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
Marek M, Shaik TB, Heimburg T, Chakrabarti A, Lancelot J, Ramos-Morales E, Da Veiga C, Kalinin D, Melesina J, Robaa D, Schmidtkunz K, Suzuki T, Holl R, Ennifar E, Pierce RJ, Jung M, Sippl W, Romier C. Marek M, et al. Among authors: Sippl W. J Med Chem. 2018 Nov 21;61(22):10000-10016. doi: 10.1021/acs.jmedchem.8b01087. Epub 2018 Nov 8. J Med Chem. 2018. PMID: 30347148
Elastin is heterogeneously cross-linked.
Schräder CU, Heinz A, Majovsky P, Karaman Mayack B, Brinckmann J, Sippl W, Schmelzer CEH. Schräder CU, et al. Among authors: Sippl W. J Biol Chem. 2018 Sep 28;293(39):15107-15119. doi: 10.1074/jbc.RA118.004322. Epub 2018 Aug 14. J Biol Chem. 2018. PMID: 30108173 Free PMC article.
A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment.
Shen J, Najafi S, Stäble S, Fabian J, Koeneke E, Kolbinger FR, Wrobel JK, Meder B, Distel M, Heimburg T, Sippl W, Jung M, Peterziel H, Kranz D, Boutros M, Westermann F, Witt O, Oehme I. Shen J, et al. Among authors: Sippl W. Cell Death Differ. 2018 Dec;25(12):2053-2070. doi: 10.1038/s41418-018-0080-0. Epub 2018 Mar 7. Cell Death Differ. 2018. PMID: 29515255 Free PMC article.
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.
Kolbinger FR, Koeneke E, Ridinger J, Heimburg T, Müller M, Bayer T, Sippl W, Jung M, Gunkel N, Miller AK, Westermann F, Witt O, Oehme I. Kolbinger FR, et al. Among authors: Sippl W. Arch Toxicol. 2018 Aug;92(8):2649-2664. doi: 10.1007/s00204-018-2234-8. Epub 2018 Jun 9. Arch Toxicol. 2018. PMID: 29947893 Free PMC article.
One-Atom Substitution Enables Direct and Continuous Monitoring of Histone Deacylase Activity.
Zessin M, Kutil Z, Meleshin M, Nováková Z, Ghazy E, Kalbas D, Marek M, Romier C, Sippl W, Bařinka C, Schutkowski M. Zessin M, et al. Among authors: Sippl W. Biochemistry. 2019 Dec 3;58(48):4777-4789. doi: 10.1021/acs.biochem.9b00786. Epub 2019 Nov 14. Biochemistry. 2019. PMID: 31682411
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