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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1915 1
1918 1
1938 1
1941 2
1946 3
1947 3
1948 3
1949 8
1950 8
1951 15
1952 17
1953 16
1954 19
1955 24
1956 14
1957 25
1958 30
1959 32
1960 32
1961 30
1962 42
1963 29
1964 110
1965 120
1966 192
1967 233
1968 269
1969 320
1970 295
1971 318
1972 286
1973 299
1974 309
1975 293
1976 321
1977 378
1978 349
1979 333
1980 388
1981 315
1982 262
1983 247
1984 431
1985 380
1986 424
1987 504
1988 544
1989 656
1990 668
1991 705
1992 820
1993 833
1994 1103
1995 1020
1996 1255
1997 1180
1998 1286
1999 1399
2000 1542
2001 1648
2002 1584
2003 1757
2004 2189
2005 2271
2006 2498
2007 2792
2008 3068
2009 3676
2010 4326
2011 5001
2012 5716
2013 6374
2014 7217
2015 8089
2016 8721
2017 9202
2018 9542
2019 10662
2020 11074
2021 10379
2022 7781
2023 6740
2024 3178

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140,807 results

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Page 1
Current status of xenotransplantation research and the strategies for preventing xenograft rejection.
Zhou Q, Li T, Wang K, Zhang Q, Geng Z, Deng S, Cheng C, Wang Y. Zhou Q, et al. Front Immunol. 2022 Jul 28;13:928173. doi: 10.3389/fimmu.2022.928173. eCollection 2022. Front Immunol. 2022. PMID: 35967435 Free PMC article. Review.
Transplantation is often the last resort for end-stage organ failures, e.g., kidney, liver, heart, lung, and pancreas. ...There are three different xenogeneic types of rejections, based on the responses and mechanisms involved. It includes hyperacute rejection (HAR), delay
Transplantation is often the last resort for end-stage organ failures, e.g., kidney, liver, heart, lung, and pancreas. ...There are t
Tumor xenograft animal models for esophageal squamous cell carcinoma.
Lee NP, Chan CM, Tung LN, Wang HK, Law S. Lee NP, et al. J Biomed Sci. 2018 Aug 29;25(1):66. doi: 10.1186/s12929-018-0468-7. J Biomed Sci. 2018. PMID: 30157855 Free PMC article. Review.
One factor contributing to this clinical dismal is the incomplete understanding of disease mechanism, for which this situation is further compounded by the presence of other limiting factors for disease diagnosis, patient prognosis and treatments. Tumor xenograft animal mo …
One factor contributing to this clinical dismal is the incomplete understanding of disease mechanism, for which this situation is further co …
Cellular Immune Responses in Islet Xenograft Rejection.
Hu M, Hawthorne WJ, Yi S, O'Connell PJ. Hu M, et al. Front Immunol. 2022 Jul 7;13:893985. doi: 10.3389/fimmu.2022.893985. eCollection 2022. Front Immunol. 2022. PMID: 35874735 Free PMC article. Review.
Although they are less important than CD4(+) T cells in islet xenograft rejection, macrophages are believed to be a major effector cell in this response. ...B cells are an important mediator of islet xenograft rejection via xenoantigen presentation, priming effector …
Although they are less important than CD4(+) T cells in islet xenograft rejection, macrophages are believed to be a major effector ce …
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation.
Griffith BP, Goerlich CE, Singh AK, Rothblatt M, Lau CL, Shah A, Lorber M, Grazioli A, Saharia KK, Hong SN, Joseph SM, Ayares D, Mohiuddin MM. Griffith BP, et al. N Engl J Med. 2022 Jul 7;387(1):35-44. doi: 10.1056/NEJMoa2201422. Epub 2022 Jun 22. N Engl J Med. 2022. PMID: 35731912 Free PMC article.
Immunosuppression was based on CD40 blockade. The patient was weaned from ECMO, and the xenograft functioned normally without apparent rejection. Sudden diastolic thickening and failure of the xenograft occurred on day 49 after transplantation, and life suppo …
Immunosuppression was based on CD40 blockade. The patient was weaned from ECMO, and the xenograft functioned normally without apparen …
Breast Cancer Xenograft Murine Models.
Fernando W, Coyle KM, Marcato P. Fernando W, et al. Methods Mol Biol. 2022;2508:31-44. doi: 10.1007/978-1-0716-2376-3_4. Methods Mol Biol. 2022. PMID: 35737231
Immunocompetent models allow the study of the impact of the immune system in murine models of mammary cancer, while immunodeficient mice serve as ideal host organisms to understand the behavior of human breast cancers within a biological system. Xenografting of human breas …
Immunocompetent models allow the study of the impact of the immune system in murine models of mammary cancer, while immunodeficient mice ser …
Xenotransplantation: A New Era.
Carrier AN, Verma A, Mohiuddin M, Pascual M, Muller YD, Longchamp A, Bhati C, Buhler LH, Maluf DG, Meier RPH. Carrier AN, et al. Front Immunol. 2022 Jun 9;13:900594. doi: 10.3389/fimmu.2022.900594. eCollection 2022. Front Immunol. 2022. PMID: 35757701 Free PMC article. Review.
This review serves as a brief discussion of the recent progress in xenotransplantation research, particularly as it concerns utilization of porcine heart, renal, and liver xenografts in clinical practice....
This review serves as a brief discussion of the recent progress in xenotransplantation research, particularly as it concerns utilization of …
Zebrafish xenograft as a tool for the study of colorectal cancer: a review.
Fontana CM, Van Doan H. Fontana CM, et al. Cell Death Dis. 2024 Jan 9;15(1):23. doi: 10.1038/s41419-023-06291-0. Cell Death Dis. 2024. PMID: 38195619 Free PMC article. Review.
Danio rerio (zebrafish) is a popular animal model utilized in cancer research. One of its main advantages is the ease of xenograft transplantation due to the fact that zebrafish larvae lack the adaptative immune system, guaranteeing the impossibility of rejection. I …
Danio rerio (zebrafish) is a popular animal model utilized in cancer research. One of its main advantages is the ease of xenograft
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation.
Montgomery RA, Stern JM, Lonze BE, Tatapudi VS, Mangiola M, Wu M, Weldon E, Lawson N, Deterville C, Dieter RA, Sullivan B, Boulton G, Parent B, Piper G, Sommer P, Cawthon S, Duggan E, Ayares D, Dandro A, Fazio-Kroll A, Kokkinaki M, Burdorf L, Lorber M, Boeke JD, Pass H, Keating B, Griesemer A, Ali NM, Mehta SA, Stewart ZA. Montgomery RA, et al. N Engl J Med. 2022 May 19;386(20):1889-1898. doi: 10.1056/NEJMoa2120238. N Engl J Med. 2022. PMID: 35584156
BACKGROUND: Xenografts from genetically modified pigs have become one of the most promising solutions to the dearth of human organs available for transplantation. ...We performed serial biopsies and monitored the urine output and kinetic estimated glomerular filtrat …
BACKGROUND: Xenografts from genetically modified pigs have become one of the most promising solutions to the dearth of human organs a …
Glioblastoma research on zebrafish xenograft models: a systematic review.
Pliakopanou A, Antonopoulos I, Darzenta N, Serifi I, Simos YV, Katsenos AP, Bellos S, Alexiou GA, Kyritsis AP, Leonardos I, Vezyraki P, Peschos D, Tsamis KI. Pliakopanou A, et al. Clin Transl Oncol. 2024 Feb;26(2):311-325. doi: 10.1007/s12094-023-03258-7. Epub 2023 Jul 3. Clin Transl Oncol. 2024. PMID: 37400666 Free PMC article. Review.
The challenges in GBM therapeutics have shed light on zebrafish used as a promising animal model for preclinical GBM xenograft studies without a standardized methodology. This systematic review aims to summarize the advances in zebrafish GBM xenografting, compare re …
The challenges in GBM therapeutics have shed light on zebrafish used as a promising animal model for preclinical GBM xenograft studie …
140,807 results
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