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Page 1
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.
Gaggero S, Martinez-Fabregas J, Cozzani A, Fyfe PK, Leprohon M, Yang J, Thomasen FE, Winkelmann H, Magnez R, Conti AG, Wilmes S, Pohler E, van Gijsel Bonnello M, Thuru X, Quesnel B, Soncin F, Piehler J, Lindorff-Larsen K, Roychoudhuri R, Moraga I, Mitra S. Gaggero S, et al. Among authors: thuru x. Sci Immunol. 2022 Dec 9;7(78):eade5686. doi: 10.1126/sciimmunol.ade5686. Epub 2022 Dec 2. Sci Immunol. 2022. PMID: 36459543
Tau Stabilizes Chromatin Compaction.
Rico T, Gilles M, Chauderlier A, Comptdaer T, Magnez R, Chwastyniak M, Drobecq H, Pinet F, Thuru X, Buée L, Galas MC, Lefebvre B. Rico T, et al. Among authors: thuru x. Front Cell Dev Biol. 2021 Oct 14;9:740550. doi: 10.3389/fcell.2021.740550. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34722523 Free PMC article.
PD-1/PD-L1 binding studies using microscale thermophoresis.
Magnez R, Thiroux B, Taront S, Segaoula Z, Quesnel B, Thuru X. Magnez R, et al. Among authors: thuru x. Sci Rep. 2017 Dec 15;7(1):17623. doi: 10.1038/s41598-017-17963-1. Sci Rep. 2017. PMID: 29247197 Free PMC article.
Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties.
Regnault R, Klupsch F, El-Bouazzati H, Magnez R, Le Biannic R, Leleu-Chavain N, Ahouari H, Vezin H, Millet R, Goossens JF, Thuru X, Bailly C. Regnault R, et al. Among authors: thuru x. Molecules. 2023 Apr 15;28(8):3491. doi: 10.3390/molecules28083491. Molecules. 2023. PMID: 37110727 Free PMC article.
Activity of pyridyl-pyrazolone derivatives against Trypanosoma cruzi.
Batista DDGJ, de Almeida Fiuza LF, Klupsch F, da Costa KN, Batista MM, da Conceição K, Bouafia H, Vergoten G, Millet R, Thuru X, Bailly C, Soeiro MNC. Batista DDGJ, et al. Among authors: thuru x. Exp Parasitol. 2024 Jul;262:108787. doi: 10.1016/j.exppara.2024.108787. Epub 2024 May 15. Exp Parasitol. 2024. PMID: 38759776 Free article.
Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson's Disease.
Coku I, Mutez E, Eddarkaoui S, Carrier S, Marchand A, Deldycke C, Goveas L, Baille G, Tir M, Magnez R, Thuru X, Vermeersch G, Vandenberghe W, Buée L, Defebvre L, Sablonnière B, Chartier-Harlin MC, Taymans JM, Huin V. Coku I, et al. Among authors: thuru x. Mov Disord. 2022 Aug;37(8):1761-1767. doi: 10.1002/mds.29124. Epub 2022 Jun 16. Mov Disord. 2022. PMID: 35708213 Free PMC article.
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